Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) virAT/YafQ(toxin)
Location 5512..6061 Replicon plasmid pR19.1007_38k
Accession NZ_CP077636
Organism Campylobacter jejuni strain R19.1007

Toxin (Protein)


Gene name virT Uniprot ID A0A5T0ZCU7
Locus tag KTN75_RS09510 Protein ID WP_014517465.1
Coordinates 5786..6061 (+) Length 92 a.a.

Antitoxin (Protein)


Gene name virA Uniprot ID A0A5T1T0M3
Locus tag KTN75_RS09505 Protein ID WP_014517464.1
Coordinates 5512..5796 (+) Length 95 a.a.

Genomic Context

KTN75_RS09455KTN75_RS09460KTN75_RS09465KTN75_RS09470KTN75_RS09475KTN75_RS09480KTN75_RS09485KTN75_RS09490KTN75_RS09495KTN75_RS09500KTN75_RS09505KTN75_RS09510KTN75_RS09515KTN75_RS09525KTN75_RS09530KTN75_RS09520
Location: 625..1053 (429 bp)
Type: Others
Protein ID: WP_014517463.1
Location: 1525..1869 (345 bp)
Type: Others
Protein ID: WP_011117579.1
Location: 1883..2191 (309 bp)
Type: Others
Protein ID: WP_052835053.1
Location: 2201..2422 (222 bp)
Type: Others
Protein ID: WP_011799395.1
Location: 2435..2830 (396 bp)
Type: Others
Protein ID: WP_011117582.1
Location: 2903..3334 (432 bp)
Type: Others
Protein ID: WP_217296015.1
Location: 3321..3752 (432 bp)
Type: Others
Protein ID: WP_002815407.1
Location: 3960..4145 (186 bp)
Type: Others
Protein ID: WP_004306057.1
Location: 4157..4327 (171 bp)
Type: Others
Protein ID: WP_002815835.1
Location: 4926..5288 (363 bp)
Type: Others
Protein ID: WP_025443372.1
Location: 5512..5796 (285 bp)
Type: Antitoxin
Protein ID: WP_014517464.1
Location: 5786..6061 (276 bp)
Type: Toxin
Protein ID: WP_014517465.1
Location: 6175..6486 (312 bp)
Type: Others
Protein ID: Protein_13
Location: 9239..9544 (306 bp)
Type: Others
Protein ID: WP_011799398.1
Location: 9544..9786 (243 bp)
Type: Others
Protein ID: WP_052835045.1
Location: 6794..8365 (1572 bp)
Type: Others
Protein ID: WP_217296016.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
KTN75_RS09455 (KTN75_09455)625..1053+429WP_014517463.1hypothetical protein-
KTN75_RS09460 (KTN75_09460)1525..1869+345WP_011117579.1hypothetical protein-
KTN75_RS09465 (KTN75_09465)1883..2191+309WP_052835053.1hypothetical protein-
KTN75_RS09470 (KTN75_09470)2201..2422+222WP_011799395.1hypothetical protein-
KTN75_RS09475 (KTN75_09475)2435..2830+396WP_011117582.1hypothetical protein-
KTN75_RS09480 (KTN75_09480)2903..3334+432WP_217296015.1hypothetical protein-
KTN75_RS09485 (KTN75_09485)3321..3752+432WP_002815407.1hypothetical protein-
KTN75_RS09490 (KTN75_09490)3960..4145+186WP_004306057.1hypothetical protein-
KTN75_RS09495 (KTN75_09495)4157..4327+171WP_002815835.1hypothetical protein-
KTN75_RS09500 (KTN75_09500)4926..5288+363WP_025443372.1hypothetical protein-
KTN75_RS09505 (KTN75_09505)5512..5796+285WP_014517464.1hypothetical proteinAntitoxin
KTN75_RS09510 (KTN75_09510)5786..6061+276WP_014517465.1type II toxin-antitoxin system YafQ family toxinToxin
KTN75_RS09515 (KTN75_09515)6175..6486+312Protein_13hypothetical protein-
KTN75_RS09520 (KTN75_09520)6794..8365-1572WP_217296016.1relaxase/mobilization nuclease domain-containing protein-
KTN75_RS09525 (KTN75_09525)9239..9544+306WP_011799398.1hypothetical protein-
KTN75_RS09530 (KTN75_09530)9544..9786+243WP_052835045.1hypothetical protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
-insideNon-Mobilizable plasmid-virB4 / Cjp54 / virB8 / virB9 / virB10 / virB11 / virD41..3824738247


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, YafQ-like toxin

(4-91)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 92 a.a.        Molecular weight: 10872.64 Da        Isoelectric Point: 10.2009

>T207244 WP_014517465.1 NZ_CP077636:5786-6061 [Campylobacter jejuni]
MQNKYSVTFSKRFKKDFKKINNNDKKILKKIVNKLANDEVLEEKYKDHALKGNYIGFRECHIKPDLLLVYRKNNDILELY
LANLGNHNNIF

Download         Length: 276 bp

>T207244 NZ_CP102946:c5485059-5484781 [Pseudomonas aeruginosa]
ATGATTCTGACCTTTCGCTGCGACGAGACTCGTCAGCTTTTTGAGACGGGTCTTTCGAGGCGGTGGGGAGCGATCCTCAC
AGTCGCTACGCGTAAGCTCGCAATGCTTCATGCGGCTACGGAGCTTCGAGACCTGCGCTCTCCACCTGGAAACCGGTTGG
AGCCGTTGCAGGGAAAGCGGGCGGGCCAACATAGCATCAGGATCAATGACCAGTGGCGTGTCTGTTTCGTCTGGACGGAT
GCGGGTCCCGAAGAAGTCGAAATAGTTGATTACCACTGA

Antitoxin


Download         Length: 95 a.a.        Molecular weight: 11082.46 Da        Isoelectric Point: 8.3991

>AT207244 WP_014517464.1 NZ_CP077636:5512-5796 [Campylobacter jejuni]
MFDYSKYENATEKQLIHALTLAEKRAEKLNSQLKENNELFKFLQKKLKNSFNTKKTKKADQRRPELDEAIEDYKNGNVEH
YANVEEAFKALNAE

Download         Length: 285 bp

>AT207244 NZ_CP102946:c5484769-5484464 [Pseudomonas aeruginosa]
ATGGCTACCAATGGTATGCGCCCCATCCATCCTGGGGAAATATTGCGCGATGAGTTTCTGATGGAGTTTGATATCTCTCC
AGCTGCTCTAGCACGCGCTTTGAAAGTCTCCGCTCCGACAGTGAACGATATCGTTCGTGAGCAGCGTGGTATCTCCGCAG
ATATGGCGATTCGTCTGGGGCGTTACTTTGATACGTCCGCTCAGTTCTGGATGAATCTCCAGAGTGAGTATTCGTTAGCA
ACTGCTTATGCGGCGAATGGCAAGCAGATCGAACATGAGATTGAGCCGCTGCTTGCTCACGGATAG

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
AlphaFold DBA0A5T0ZCU7

Antitoxin

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Source
ID
Structure
AlphaFold DBA0A5T1T0M3

References