Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | relBE/ParE-Phd |
| Location | 1035382..1035929 | Replicon | chromosome |
| Accession | NZ_CP077425 | ||
| Organism | Vibrio mimicus strain Y4 | ||
Toxin (Protein)
| Gene name | relE | Uniprot ID | A0A0H3AD26 |
| Locus tag | KSS82_RS04865 | Protein ID | WP_000807826.1 |
| Coordinates | 1035627..1035929 (+) | Length | 101 a.a. |
Antitoxin (Protein)
| Gene name | relB | Uniprot ID | - |
| Locus tag | KSS82_RS04860 | Protein ID | WP_217009250.1 |
| Coordinates | 1035382..1035639 (+) | Length | 86 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| KSS82_RS04815 (KSS82_04815) | 1030619..1031398 | + | 780 | WP_217009247.1 | hypothetical protein | - |
| KSS82_RS04820 (KSS82_04820) | 1031609..1031878 | + | 270 | WP_001114075.1 | DUF4160 domain-containing protein | - |
| KSS82_RS04825 (KSS82_04825) | 1031872..1032393 | + | 522 | WP_217009248.1 | DUF2442 domain-containing protein | - |
| KSS82_RS20590 | 1032454..1032519 | + | 66 | Protein_981 | acetyltransferase | - |
| KSS82_RS04830 (KSS82_04830) | 1032690..1032815 | + | 126 | Protein_982 | DUF645 family protein | - |
| KSS82_RS20595 | 1032781..1032897 | + | 117 | WP_001952129.1 | hypothetical protein | - |
| KSS82_RS04840 (KSS82_04840) | 1033201..1034133 | + | 933 | WP_002044844.1 | hypothetical protein | - |
| KSS82_RS04845 (KSS82_04845) | 1034117..1034545 | + | 429 | WP_217009224.1 | hypothetical protein | - |
| KSS82_RS04850 (KSS82_04850) | 1034629..1034742 | + | 114 | WP_217009249.1 | iron transporter | - |
| KSS82_RS04855 (KSS82_04855) | 1034708..1035190 | + | 483 | WP_000422937.1 | GNAT family protein | - |
| KSS82_RS04860 (KSS82_04860) | 1035382..1035639 | + | 258 | WP_217009250.1 | type II toxin-antitoxin system Phd/YefM family antitoxin | Antitoxin |
| KSS82_RS04865 (KSS82_04865) | 1035627..1035929 | + | 303 | WP_000807826.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
| KSS82_RS04870 (KSS82_04870) | 1036243..1036425 | + | 183 | WP_217009251.1 | DUF645 family protein | - |
| KSS82_RS04875 (KSS82_04875) | 1036626..1036973 | + | 348 | WP_039485626.1 | hypothetical protein | - |
| KSS82_RS20600 | 1036973..1037035 | + | 63 | Protein_992 | DUF3265 domain-containing protein | - |
| KSS82_RS04880 (KSS82_04880) | 1037148..1037486 | + | 339 | WP_000070992.1 | hypothetical protein | - |
| KSS82_RS04885 (KSS82_04885) | 1037838..1039027 | + | 1190 | WP_088124793.1 | IS3 family transposase | - |
| KSS82_RS04890 (KSS82_04890) | 1039160..1039447 | + | 288 | WP_005521414.1 | hypothetical protein | - |
| KSS82_RS04895 (KSS82_04895) | 1039584..1040399 | + | 816 | WP_217009252.1 | hypothetical protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Integron | - | cqsA / hlyA / vgrG-3 / vasL / icmF/vasK / vasJ / vasI / vasH / clpB/vasG / vasF / vasE / vasD / vasC / vasB / vasA / VCA0109 / vipB/mglB / vipA/mglA / vgrG-2 / hcp-2 / hlyA | 1..1082609 | 1082608 | |
| - | inside | Genomic island | - | - | 980684..1079830 | 99146 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 101 a.a. Molecular weight: 11725.65 Da Isoelectric Point: 5.1972
>T207229 WP_000807826.1 NZ_CP077425:1035627-1035929 [Vibrio mimicus]
MAEIIWTEPALSDLNDIAEYIALENVVAAKQLVQTVFTKVERLADFPESGRVPLELEHLNYREVVVNPCRVFYKYDDAKV
RILFVMRAERDLRRLMLTKQ
MAEIIWTEPALSDLNDIAEYIALENVVAAKQLVQTVFTKVERLADFPESGRVPLELEHLNYREVVVNPCRVFYKYDDAKV
RILFVMRAERDLRRLMLTKQ
Download Length: 303 bp
>T207229 NZ_CP102945:c814674-814486 [Staphylococcus aureus]
ATGTCTTTACATTTTGCAATTCTGTTTTGGCTAGCATTAATTTTCTTAGTTGCCGCTACGTTTATACTCGTATTAATGAA
AAAAACTGGCAAAGAATCTAAAAAAGAGTCCTATTTAAGTTTCACTGTCATTCTCTATATTTTTGGATTCGCTATATTAA
TATACACATTTATATTTGGTGTGCTATAA
ATGTCTTTACATTTTGCAATTCTGTTTTGGCTAGCATTAATTTTCTTAGTTGCCGCTACGTTTATACTCGTATTAATGAA
AAAAACTGGCAAAGAATCTAAAAAAGAGTCCTATTTAAGTTTCACTGTCATTCTCTATATTTTTGGATTCGCTATATTAA
TATACACATTTATATTTGGTGTGCTATAA
Antitoxin
Download Length: 86 a.a. Molecular weight: 9677.18 Da Isoelectric Point: 7.3178
>AT207229 WP_217009250.1 NZ_CP077425:1035382-1035639 [Vibrio mimicus]
MKVELVTSLKRQATKILADLHDTKEPVLITEHGKPSAYLIDVDDYEFMQNRLAILEGITRGERALADGKVVSHQDAKDRM
SKWLK
MKVELVTSLKRQATKILADLHDTKEPVLITEHGKPSAYLIDVDDYEFMQNRLAILEGITRGERALADGKVVSHQDAKDRM
SKWLK
Download Length: 258 bp
>AT207229 NZ_CP102945:c814963-814703 [Staphylococcus aureus]
ATGAATAACATTTTGTTAAATGCTATCAATATAGTTATTACTACCACTTTTGTTATCTTTAATATTTTAATCACATATAA
TAAAGATTTAGATGATTTATGTTGGCTCCTGCCTGGTATTATCATTTGTGGTGTGATACTCATCGTATCCTTTACCATTG
CAATGATAACTAAAAACTGGTTAAGTGAAATATTATTTTTTATAAATATCGTACTCGTTCTCTATTACATTTATCCTATT
TTTTATAGTTTTATAGGTTAA
ATGAATAACATTTTGTTAAATGCTATCAATATAGTTATTACTACCACTTTTGTTATCTTTAATATTTTAATCACATATAA
TAAAGATTTAGATGATTTATGTTGGCTCCTGCCTGGTATTATCATTTGTGGTGTGATACTCATCGTATCCTTTACCATTG
CAATGATAACTAAAAACTGGTTAAGTGAAATATTATTTTTTATAAATATCGTACTCGTTCTCTATTACATTTATCCTATT
TTTTATAGTTTTATAGGTTAA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|