Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/ParE-Phd
Location 10233..10811 Replicon chromosome
Accession NZ_CP077425
Organism Vibrio mimicus strain Y4

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag KSS82_RS00090 Protein ID WP_217009281.1
Coordinates 10233..10550 (-) Length 106 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID -
Locus tag KSS82_RS00095 Protein ID WP_001961623.1
Coordinates 10569..10811 (-) Length 81 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KSS82_RS00050 (KSS82_00050) 5401..5772 + 372 WP_001164077.1 MazG nucleotide pyrophosphohydrolase domain-containing protein -
KSS82_RS00055 (KSS82_00055) 5795..6754 - 960 WP_217009278.1 IS30 family transposase -
KSS82_RS00060 (KSS82_00060) 7030..7383 + 354 WP_207805190.1 nuclear transport factor 2 family protein -
KSS82_RS00065 (KSS82_00065) 7527..8024 + 498 WP_142565236.1 GNAT family N-acetyltransferase -
KSS82_RS00070 (KSS82_00070) 8127..8426 - 300 WP_217009279.1 type II toxin-antitoxin system RelE/ParE family toxin -
KSS82_RS00075 (KSS82_00075) 8423..8665 - 243 WP_001107720.1 type II toxin-antitoxin system ParD family antitoxin -
KSS82_RS20425 9032..9121 + 90 WP_001905720.1 DUF645 family protein -
KSS82_RS20430 9157..9213 + 57 WP_088129470.1 DUF645 family protein -
KSS82_RS00085 (KSS82_00085) 9411..10130 + 720 WP_217009280.1 hypothetical protein -
KSS82_RS00090 (KSS82_00090) 10233..10550 - 318 WP_217009281.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
KSS82_RS00095 (KSS82_00095) 10569..10811 - 243 WP_001961623.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
KSS82_RS00100 (KSS82_00100) 11201..11382 + 182 Protein_23 DUF645 family protein -
KSS82_RS00105 (KSS82_00105) 11596..12171 + 576 WP_217009282.1 sugar O-acetyltransferase -
KSS82_RS00110 (KSS82_00110) 12468..12647 + 180 WP_069730859.1 DUF645 family protein -
KSS82_RS00115 (KSS82_00115) 12850..13608 + 759 WP_217009225.1 hypothetical protein -
KSS82_RS20435 13665..13727 + 63 Protein_27 acetyltransferase -
KSS82_RS00120 (KSS82_00120) 13767..14684 + 918 WP_217009283.1 ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Integron - cqsA / hlyA / vgrG-3 / vasL / icmF/vasK / vasJ / vasI / vasH / clpB/vasG / vasF / vasE / vasD / vasC / vasB / vasA / VCA0109 / vipB/mglB / vipA/mglA / vgrG-2 / hcp-2 / hlyA 1..1082609 1082608


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(6-93)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-71)


Sequences

Toxin        


Download         Length: 106 a.a.        Molecular weight: 12144.95 Da        Isoelectric Point: 9.7495

>T207217 WP_217009281.1 NZ_CP077425:c10550-10233 [Vibrio mimicus]
MQNKQYKLSQLAQEHLLKVKHYTIENFAEAQWQKYKSTLLSGFQTLADNPGLGKSCEDIYQNGFYFPVGKHMAYYTKEAN
FILIVAVLGQSQLPQKHLKQSRFVS

Download         Length: 318 bp

>T207217 NZ_CP102942:c108640-107318 [Stenotrophomonas maltophilia]
ATGGGTACGCTGCAGGTCTGGATGAATGGTGTGGAAGTCGCACTTTGGGATGATGTCCGGAACGGGTCACCCCGGTTGTC
GTATGTCAGCCAGTGGATCAGCTCGCCCCAGTCCCGACCGTTGTCGCTCTCTCTACCCCTGCTCCCAGATGGCGAGAGCC
ATCGGGGCAACGTCGTCAACGACTACTTCGATAACCTTCTTCCCGATAACGTCGCCATACGCAACCGGATCCGCGACCGG
TTCGCCACGCGCGGCAGCGATACGTTCGATCTTCTTGAAGCCATTGGACGGGATTGTGTCGGCGCAGTGCAGCTGTTGCC
GCCTGCGCATCCACCCGAAGACATCCAGCAGATCACGTGCGAGGTGTTGGACGAAGCAGGTGTCGCTACGATCCTGCGTC
AGGTGACGACAGGGAACCTGCCTGGCGCACCCAGCCGTGATGATGCATTCCGCATTTCCATCGCCGGTGCGCAGGAAAAG
ACCGGTCTTCTGCTGCATGCTGGCAAATGGTGCATTCCTACCGGCAACACACCATCCACTCACATCTTCAAGCTGCCGCT
TGGCATTGTTGGCAACATGCGGGCAGACATGCATCAGTCCGTGGAGAATGAATGGCTGTGCATGCATCTGCTTTCCGCTT
TTGATATCCCCGTGGCCGAGACGCAGATGGGCCGCTTCAACGACCAACGTGCTCTCATTGTCGAGCGGTTTGACCGTCGC
CTGTCTGCCGACCGCCGGTGGTGGCTGCGACTGCCACAGGAAGACATGTGTCAGGTCTTTGGTCTGCCGGCTGCCAGAAA
GTATGAATCCGATGGCGGCCCCGGTATCGTTCCGATCATGGATCTGCTTCGACAGTCCGAACACCCCGAGGATCGCGCGA
TCTTCTTCAAGACGCAGATTCTTTTCTGGATGCTGGCCGCAACCGACGGCCATGCCAAGAATTTCAGTGTTCACCTGGAA
GCCGGTGGACGCTTCCGCCTGACGCCCGTCTACGACGTGCTGTCGGTATATCCCATCCTCGGCAGGGGACCCAATCAACT
CGATCCACGAAACGCACAGCTCGCCATGGCCGTACATGGCAAGAACCGCCACCGGAAACTGCACCTTGTGCGACGGCGGC
ACTGGAATGAAACCGCGCGCGCCTGCGGCGTTGCCGATGGTGCAGAACCATGGATCAAGACATTGATCGCGGCCGTCGAG
CCCGCCATCCAGCAGGTCACCCGTCAGCTCCCGGATGACTTCCCCTCAAACGTGTCCGAACCGATTTTCAACGGACTTCG
TGCTGCGGCAGCACGCCTTTCCAGCATGGCCCCCGAGGCTTGA

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 8931.22 Da        Isoelectric Point: 5.6630

>AT207217 WP_001961623.1 NZ_CP077425:c10811-10569 [Vibrio mimicus]
MHTLTANDAKRNFGELLLSAQREPVIISKNSKNTVVVMSIKDFEELEAMKLDYLKHCFESAQKDLDGGKTVDGATFLNTL

Download         Length: 243 bp

>AT207217 NZ_CP102942:c108901-108644 [Stenotrophomonas maltophilia]
ATGGACAGGCCGCTGCACACAGTGAGGACAGCCCAACAACTTGCGCCCCTGATGCGTGCTTTCCGGCGCCAGGCGGGCCT
GAGCCAGGCTCAGCTGGCGGAGCGACTCGGGATCAGCCGCCAGGCAGTGGGCGCGCTGGAACGCGACCCTGCATCGGCAA
GTTTTGAACGCCTGATGCGGATCTGGGCGGTGCTGGGTCTGGAGGTCAGCCTCCAGCAACGAAGTCCCCAGGAGAACACG
TCGTCATTGGAGTGGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References