Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) hipBA/HipA-HipB
Location 4915833..4917418 Replicon chromosome
Accession NZ_CP077422
Organism Dickeya dadantii strain M2-3

Toxin (Protein)


Gene name hipA Uniprot ID -
Locus tag KTF62_RS21955 Protein ID WP_171852778.1
Coordinates 4916099..4917418 (+) Length 440 a.a.

Antitoxin (Protein)


Gene name hipB Uniprot ID -
Locus tag KTF62_RS21950 Protein ID WP_077246343.1
Coordinates 4915833..4916099 (+) Length 89 a.a.

Genomic Context

KTF62_RS21930KTF62_RS21940KTF62_RS21945KTF62_RS21950KTF62_RS21955KTF62_RS21925KTF62_RS21935KTF62_RS21960KTF62_RS21965KTF62_RS21970KTF62_RS21975KTF62_RS21980
Location: 4911885..4912265 (381 bp)
Type: Others
Protein ID: WP_033112454.1
Location: 4913790..4914563 (774 bp)
Type: Others
Protein ID: WP_033112166.1
Location: 4914606..4915583 (978 bp)
Type: Others
Protein ID: WP_171861132.1
Location: 4915833..4916099 (267 bp)
Type: Antitoxin
Protein ID: WP_077246343.1
Location: 4916099..4917418 (1320 bp)
Type: Toxin
Protein ID: WP_171852778.1
Location: 4911131..4911742 (612 bp)
Type: Others
Protein ID: WP_013320111.1
Location: 4912390..4913475 (1086 bp)
Type: Others
Protein ID: WP_161450993.1
Location: 4917490..4918854 (1365 bp)
Type: Others
Protein ID: WP_161450991.1
Location: 4918970..4920601 (1632 bp)
Type: Others
Protein ID: WP_161450990.1
Location: 4920617..4920862 (246 bp)
Type: Others
Protein ID: WP_171861131.1
Location: 4920826..4921185 (360 bp)
Type: Others
Protein ID: WP_013320101.1
Location: 4921204..4921344 (141 bp)
Type: Others
Protein ID: WP_004093983.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
KTF62_RS21925 (KTF62_21855)4911131..4911742-612WP_013320111.1NAD(P)-dependent oxidoreductase-
KTF62_RS21930 (KTF62_21860)4911885..4912265+381WP_033112454.1helix-turn-helix domain-containing protein-
KTF62_RS21935 (KTF62_21865)4912390..4913475-1086WP_161450993.14-hydroxyphenylpyruvate dioxygenase-
KTF62_RS21940 (KTF62_21870)4913790..4914563+774WP_033112166.1MBL fold metallo-hydrolase-
KTF62_RS21945 (KTF62_21875)4914606..4915583+978WP_171861132.1helix-turn-helix domain-containing protein-
KTF62_RS21950 (KTF62_21880)4915833..4916099+267WP_077246343.1helix-turn-helix domain-containing proteinAntitoxin
KTF62_RS21955 (KTF62_21885)4916099..4917418+1320WP_171852778.1type II toxin-antitoxin system HipA family toxinToxin
KTF62_RS21960 (KTF62_21890)4917490..4918854-1365WP_161450991.1tRNA uridine-5-carboxymethylaminomethyl(34) synthesis GTPase MnmE-
KTF62_RS21965 (KTF62_21895)4918970..4920601-1632WP_161450990.1membrane protein insertase YidC-
KTF62_RS21970 (KTF62_21900)4920617..4920862-246WP_171861131.1membrane protein insertion efficiency factor YidD-
KTF62_RS21975 (KTF62_21905)4920826..4921185-360WP_013320101.1ribonuclease P protein component-
KTF62_RS21980 (KTF62_21910)4921204..4921344-141WP_004093983.150S ribosomal protein L34-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

HipA, N-terminal subdomain 1

(4-103)

Antitoxin

Cro/C1-type helix-turn-helix domain

(13-65)


Sequences

Toxin        


Download         Length: 440 a.a.        Molecular weight: 49355.52 Da        Isoelectric Point: 7.5718

>T207211 WP_171852778.1 NZ_CP077422:4916099-4917418 [Dickeya dadantii]
MAALDVYMNGYRVGILTKTGSGAHHFSYDANWLGLPGNRPISLSMPLRHQPYQGDEVYNFFDNLLPDNPDIRRRIVARHH
ADSTQPFDLLAKVGQDSVGALQLVPQGIPARDIKQIEYKTLSEQQLESILSGYLSDAPLGMIDTEDDFRISIAGAQEKTA
LLYLDNHWCLPFNTTPTTHIIKLPIGKIESHSYSIDMSDSVENEYLCLLIARAFGLPVPHCFMIKAGKIKALAVERFDRK
YASDGSWIMRLPQEDFCQVLNVPSALKYENHGGPGISAIMSYLLGAVDPQRDRYSFMKAQVLFWLLAATDGHAKNFSLFI
ESEGRYRLTPFYDILSMYPAFGGRGIDRRDAKLAMGLAGTRGKKYHIEKIFPRHFFQTAKAVGFARESMERILTEFSQTV
DSVIVSVRNQLPADFPTPIRDAILGGLQTRSRRLTTGWE

Download         Length: 1320 bp

>T207211 NZ_CP102940:c3909387-3909070 [Klebsiella pneumoniae]
ATGTTCAGATTGGTTGTGCATGTGGACGTTAAAAAGGAATTGCAGGCGCTTCCGCCCATTGTCCAGGCGAAGATGATCCG
GCAATTAGACAAGTTACGCCAAAATCCCACCGCGCTGAGAGAACCTGACAGTAAACCGCTGGGGCAGGGGCTATTTGAAA
TTCGTGCGTTAGGTTCGGTACAGGGGCGAGGGATCTACGTTTTTCAGCAAGGCAAGACGCTCTTTCTGCTACGGGTTTTT
GTCAAGAAAACGCAAAAAACCCCGTCATCGGAAATTCGCCTGGCGCTGAAGCGATTAGAGGAGATGCGCAATGAGTAA

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 9913.32 Da        Isoelectric Point: 9.7281

>AT207211 WP_077246343.1 NZ_CP077422:4915833-4916099 [Dickeya dadantii]
MKVTNAKQLSSYLKDVRIMQKLSQGKVASKVGIRQDTVSSFEQHPDSTKLETFFKILSALNLELTVTPRNMDAANNEASV
APSWKEEW

Download         Length: 267 bp

>AT207211 NZ_CP102940:c3909077-3908790 [Klebsiella pneumoniae]
ATGAGTAAAAAGATCATTGACTGGGATACGTTAAAAACAGAACTGCTTGGCCAGCCTGAGGTTCAGGCTGCATTCGATGC
GCAAGAACGTCAACAGCGATTACGTACTATGCTGGCGCAATGGCGCGAGCAGGCGGGGCTAACCCGAGCCCAGGTGGCGC
AGAGGATGGGGGTGAGTGCGCCGACAGTCTCCAGAATGGAAGCCAATATCACCCGCGCCAGTCTGGATACCTTAACGCGA
TACGCGTTAGCCTGCGGTATAAAGCACCCGCAAGTTTTACTTTACTAA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References