Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) DhiAT/dnstrm_HI1420(antitoxin)
Location 1654995..1655749 Replicon chromosome
Accession NZ_CP077422
Organism Dickeya dadantii strain M2-3

Toxin (Protein)


Gene name dhiT Uniprot ID -
Locus tag KTF62_RS07550 Protein ID WP_033111742.1
Coordinates 1654995..1655252 (+) Length 86 a.a.

Antitoxin (Protein)


Gene name dhiA Uniprot ID -
Locus tag KTF62_RS07555 Protein ID WP_077246089.1
Coordinates 1655261..1655749 (+) Length 163 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KTF62_RS07540 (KTF62_07495) 1651757..1653907 - 2151 WP_013317224.1 formate dehydrogenase subunit alpha -
KTF62_RS07545 (KTF62_07500) 1653942..1654484 - 543 WP_013317225.1 4Fe-4S dicluster domain-containing protein -
KTF62_RS07550 (KTF62_07505) 1654995..1655252 + 258 WP_033111742.1 DUF4160 domain-containing protein Toxin
KTF62_RS07555 (KTF62_07510) 1655261..1655749 + 489 WP_077246089.1 addiction module antitoxin Antitoxin
KTF62_RS07560 (KTF62_07515) 1655828..1656322 - 495 WP_038922337.1 hydrogenase maturation peptidase HycI -
KTF62_RS07565 (KTF62_07520) 1656315..1656710 - 396 WP_224062780.1 formate hydrogenlyase maturation HycH family protein -
KTF62_RS07570 (KTF62_07525) 1656707..1657498 - 792 WP_161451815.1 NADH-quinone oxidoreductase subunit B family protein -
KTF62_RS07575 (KTF62_07530) 1657495..1658064 - 570 WP_038910722.1 hydrogenase 4 subunit H -
KTF62_RS07580 (KTF62_07535) 1658075..1659802 - 1728 WP_171859694.1 hydrogenase large subunit -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Protein of unknown function DUF4160

(9-73)

Antitoxin

Uncharacterized protein HI1420

(81-157)


Sequences

Toxin        


Download         Length: 86 a.a.        Molecular weight: 9972.56 Da        Isoelectric Point: 7.5550

>T207201 WP_033111742.1 NZ_CP077422:1654995-1655252 [Dickeya dadantii]
MPEIDRLAGLIFYLYFYDDGRHHQPHVHVCYGDDELIIAIDTGIEIEGYLPNSKRKMAIRHINAHRQHLLEMWKLAVKGR
HPGKL

Download         Length: 258 bp

>T207201 NZ_CP102934:c3334146-3333757 [Acinetobacter sp. AOR07_HL]
TTGATCAACCATTTGAATTTTAAGCTGAAATATAGTCGTTTTTCGATTATATTTCAGTTTTTTATTGGCTTAAGCTTAGC
AATTCTATTTTATCAATTAATGCCGTTACTATGGTGGTTAGTTGTAATCAGCTTACTATTTATCAGCTTTATTTTCTTTT
TAAAGCGTCCGCAGCTTGCACAAATTGCTTATTTAGATAAAAAACTATGGTCGCTTGCTTATCACTCACAGAACACCATT
TCACGCGTCAAAATTTTAAAAATAATTGATTATCAGATTTTCATAGTGATCTATTTTGAAGGTCATAAAACACTAACTTC
TATCATTTGGTTTGATCAAATGTCATTAGTAGAGTGGAAAAAGCTTAAAACTTTAGAAAAACTCTATTAA

Antitoxin


Download         Length: 163 a.a.        Molecular weight: 17861.46 Da        Isoelectric Point: 6.9790

>AT207201 WP_077246089.1 NZ_CP077422:1655261-1655749 [Dickeya dadantii]
MHKIIDVDVTGDFSLRLTYEDGLICDVDLYQYAPGPVFSNASLFIKFGLLPDGALEWLPDIKISASDLRKKGVYVGHTLA
VRERHFADVISRAFYDAVIENRPEILQAALKTAVEKHGNSTVAKEAGAKSRTSLYKSLNKNTNVSLATVVSLAHTVLQLE
EK

Download         Length: 489 bp

>AT207201 NZ_CP102934:c3334410-3334153 [Acinetobacter sp. AOR07_HL]
ATGTCTGAAGAAATGACCTTGGAAGAACGTAAAGTAATCTATCGCGCACGTCGTGGTTTAAAGGAAATTGATGTCTATTT
TGACCCTTATGTGAAAAATTATTATTTAAAGGCAGACCCGGCAGAAAAAGCGTTGTTTGCTGAGTTGGTAGAACAGGAAG
ATCCTGATTTACTCGATTGGTTTATGGAAGTATCAGAACCACCACGTACCGAATTACGTGACTTTATCTATAAATTAAAA
CACTATGTTCATGGTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References