Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) Hha-TomB/-
Location 1252513..1253138 Replicon chromosome
Accession NZ_CP077422
Organism Dickeya dadantii strain M2-3

Toxin (Protein)


Gene name Hha Uniprot ID E0SD87
Locus tag KTF62_RS05755 Protein ID WP_009114000.1
Coordinates 1252513..1252716 (-) Length 68 a.a.

Antitoxin (Protein)


Gene name TomB Uniprot ID E0SD88
Locus tag KTF62_RS05760 Protein ID WP_013316870.1
Coordinates 1252770..1253138 (-) Length 123 a.a.

Genomic Context

KTF62_RS05725KTF62_RS05730KTF62_RS05740KTF62_RS05735KTF62_RS05745KTF62_RS05755KTF62_RS05760KTF62_RS05765KTF62_RS05770KTF62_RS05775
Location: 1248171..1248509 (339 bp)
Type: Others
Protein ID: WP_002208627.1
Location: 1248552..1249844 (1293 bp)
Type: Others
Protein ID: WP_013316866.1
Location: 1251037..1251594 (558 bp)
Type: Others
Protein ID: WP_224062704.1
Location: 1249939..1250802 (864 bp)
Type: Others
Protein ID: WP_038900569.1
Location: 1251625..1251954 (330 bp)
Type: Others
Protein ID: WP_171852390.1
Location: 1252513..1252716 (204 bp)
Type: Toxin
Protein ID: WP_009114000.1
Location: 1252770..1253138 (369 bp)
Type: Antitoxin
Protein ID: WP_013316870.1
Location: 1253646..1253789 (144 bp)
Type: Others
Protein ID: WP_013316871.1
Location: 1253805..1254056 (252 bp)
Type: Others
Protein ID: WP_013316872.1
Location: 1254236..1257382 (3147 bp)
Type: Others
Protein ID: WP_013316873.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
KTF62_RS05725 (KTF62_05695)1248171..1248509+339WP_002208627.1P-II family nitrogen regulator-
KTF62_RS05730 (KTF62_05700)1248552..1249844+1293WP_013316866.1ammonium transporter AmtB-
KTF62_RS05735 (KTF62_05705)1249939..1250802-864WP_038900569.1acyl-CoA thioesterase II-
KTF62_RS05740 (KTF62_05710)1251037..1251594+558WP_224062704.1YbaY family lipoprotein-
KTF62_RS05745 (KTF62_05715)1251625..1251954-330WP_171852390.1MGMT family protein-
KTF62_RS05755 (KTF62_05725)1252513..1252716-204WP_009114000.1HHA domain-containing proteinToxin
KTF62_RS05760 (KTF62_05730)1252770..1253138-369WP_013316870.1Hha toxicity modulator TomBAntitoxin
KTF62_RS05765 (KTF62_05735)1253646..1253789-144WP_013316871.1type B 50S ribosomal protein L36-
KTF62_RS05770 (KTF62_05740)1253805..1254056-252WP_013316872.1type B 50S ribosomal protein L31-
KTF62_RS05775 (KTF62_05745)1254236..1257382-3147WP_013316873.1efflux RND transporter permease subunit-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Haemolysin expression modulating, HHA

(8-64)

Antitoxin

Biofilm formation regulator YbaJ

(1-118)


Sequences

Toxin        


Download         Length: 68 a.a.        Molecular weight: 8133.51 Da        Isoelectric Point: 8.8500

>T207200 WP_009114000.1 NZ_CP077422:c1252716-1252513 [Dickeya dadantii]
MKKIDYLMRLRKCTTIDTLERVIEKNKYELSNDELEMFYSAADHRLAELTMNKLYDKVPTAVWKYVR

Download         Length: 204 bp

>T207200 NZ_CP102933:c1242122-1241376 [Bacillus velezensis]
ATGCTTTTGTTTTTTCAGATCATGGTGTGGACGATGGCGGCCGCACTCATTTTATATGTGTACGCATCCTGGCGGTATGA
GGCAAAGGTGAAAGAAAAAATGTTTGCCATCCGTAAAACGTGGTATTTACTATTTGTACTGGGCTCCATGGTCTATTGGA
CATATGATCCTGAATCGCTCTTTGCCGCATGGAGACAATATTTGATTGTTGCCGTCTGCTTTGCCCTTATTGATGCGTTT
ATCTTTTTGAGCGCGTATATCAAAAAGCTCGCCGGCAATGAATTAGAGACGGATACGCGGGAAATTTTAGAAGAAAATAA
CGAAATGCTTCACTCCTATCTTGAAAAACTGAAAACCTATCAATATCTGTTGAAAAATGAACCGATCCATGTATATTATG
GAAGTACAGAAGCTTATGCGGAAGGCATCAGCAGACTGCTGGCCGCTTATGCCGAAAAAATGAATGTCACGGCTTCCTTG
TGCGACTATTCCGCACAATCGGATAAGGACCGCTTGACGGAGCATATGCCTGATGCGGCAGACGTTCAGTCCCGTCTTAA
CCGTAAAGACGTCTACTATGATCAAAAAGGCAGGCTTGTGCTTATTCCGTTTACAGTCCAGAACCGCCATTACGTGATCA
AACTCACGTCGGAAAACCTGTTGACGGAATTCGATTATTTGCTTTTCACATCGCTAACGAGCATTTATGATTTAATGCTG
CCAATAGAAGAGGAAGGTGACGGTTAA

Antitoxin


Download         Length: 123 a.a.        Molecular weight: 14242.11 Da        Isoelectric Point: 5.1811

>AT207200 WP_013316870.1 NZ_CP077422:c1253138-1252770 [Dickeya dadantii]
MDEYTPQHYDIAQLRFLCENLHDESIATLGDSSRGWVNDPTSAVNLQLNELIEHIAAFVVTYKIKYPHEAALCERVEKYL
DDTYILFSNYGINDTELRKWQKSKSQLFRMFSEKSICTVVKT

Download         Length: 369 bp

>AT207200 NZ_CP102933:c1241375-1241205 [Bacillus velezensis]
ATGGAGCAGGCATTTCAAAACGGGCAGCCGGAACAAAGAGCGAAACCGTTCAAAATGTTTAAAAAACGTTCAATGACAAG
TATCGCAAGTTACCAGGTCAGCCCTCATACCGCCAGAATTTTCAAAGAAAACGAGCGGCTGATTGACAAGTATAAACAAA
AAAAAGCTTGA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
AlphaFold DBA0A1X3RNQ0

Antitoxin

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Source
ID
Structure
AlphaFold DBE0SD88

References