Detailed information of TA system TA207197

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/ParE-YafN
• Location: 4855302..4855837
• Replicon: chromosome
• Accession: NZ_CP077421
• Organism: Pectobacterium polaris strain QK413-1

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: KSL88_RS21770
• Protein ID: WP_174866994.1
• Coordinates: 4855550..4855837 (+)
• Length: 96 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: Q6DB37
• Locus tag: KSL88_RS21765
• Protein ID: WP_010281712.1
• Coordinates: 4855302..4855553 (+)
• Length: 84 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
KSL88_RS21735 (KSL88_21690)	4850752..4851078	+	327	WP_095701130.1	helix-turn-helix domain-containing protein	-
KSL88_RS21740 (KSL88_21695)	4851063..4851377	+	315	WP_095701129.1	HipA N-terminal domain-containing protein	-
KSL88_RS21745 (KSL88_21700)	4851374..4852414	+	1041	WP_224072814.1	HipA domain-containing protein	-
KSL88_RS21750 (KSL88_21705)	4852474..4853097	-	624	WP_224072815.1	LysE family translocator	-
KSL88_RS21755 (KSL88_21710)	4853352..4854107	+	756	WP_224072816.1	thiol:disulfide interchange protein DsbG	-
KSL88_RS21760 (KSL88_21715)	4854141..4855046	-	906	WP_224072817.1	siderophore-interacting protein	-
KSL88_RS21765 (KSL88_21720)	4855302..4855553	+	252	WP_010281712.1	type II toxin-antitoxin system Phd/YefM family antitoxin	Antitoxin
KSL88_RS21770 (KSL88_21725)	4855550..4855837	+	288	WP_174866994.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
KSL88_RS21775 (KSL88_21730)	4855940..4857292	-	1353	WP_224072818.1	glutathione-disulfide reductase	-
KSL88_RS21780 (KSL88_21735)	4857421..4858263	-	843	WP_174870167.1	23S rRNA (adenine(2030)-N(6))-methyltransferase RlmJ	-
KSL88_RS21785 (KSL88_21740)	4858553..4858936	-	384	WP_224072819.1	TfoX/Sxy family protein	-
KSL88_RS21790 (KSL88_21745)	4859058..4860413	-	1356	WP_219680340.1	alkyl/aryl-sulfatase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (5-84)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 96 a.a.
• Molecular weight: 11143.26 Da
• Isoelectric Point: 10.4703

>T207197 WP_174866994.1 NZ_CP077421:4855550-4855837 [Pectobacterium polaris]
MSYRVKFREDALKEWLKLDKTIQQQFAKKLKKCCENPHIPSAKLRGMKDCYKIKLRASGFRLVYEVIDDVLIIAVVAVGK
RERSGVYHLASERMR

Nucleotide

• Length: 288 bp

>T207197 NZ_CP102932:c3836918-3836508 [Enterobacter sp. Crenshaw]
GTGGTCCTGTGGCAATCTGATCTTCGCGTCTCGTGGCGCTCGCAGTGGATGTCTTTATTGCTCCACGGCCTGGTTGCGGC
CTTTGTTTTGCTGATGCCGTGGCCGCTGAGCTATACGCCGCTGTGGCTGCTGTTACTGTCGTTTGTCGTTTTTGACAGCG
TACGCAGCCAGCGTCGCATTAATGCCCGTCAGGGAGAGATTAAATTACTGATGGATTCCCGCCTGCGCTGGCAGGGTAAA
GAGTGGGATATTCTCGGTATGCCCTGGATGCTCAACTGCGGCATGATGTTACGGTTACGCAAGGTGGACGGCGGGCGTTG
CCAGCATCTGTGGCTGGCGGCTGACAGTATGGATGCTGCCGAGTGGCGAGACCTGCGCCGGATGCTGTCGCAACAGACGA
CGCAGGGGTAA

Antitoxin

Protein

• Length: 84 a.a.
• Molecular weight: 9117.47 Da
• Isoelectric Point: 4.0637

>AT207197 WP_010281712.1 NZ_CP077421:4855302-4855553 [Pectobacterium polaris]
MPNIILSDTSASVSELKKNPMATVNAGDGLPVAILNRNQPAFYCIPADLYEKMLDALDDQELVKLIGERKNQPLVDVDLD
SFL

Nucleotide

• Length: 252 bp

>AT207197 NZ_CP102932:c3837165-3836899 [Enterobacter sp. Crenshaw]
ATGGATATTAACAACAAGGCCCGTATTCACTGGGCGTGCCGTCGCGGCATGCGTGAACTTGATATTTCCATCATGCCTTT
CTTCGAATATGAGTATGACAGCTTAAGCGATGATGATAAGCGTCTGTTTGTTCGCCTGCTTGAGTCTGACGATCCGGATT
TATTCAACTGGCTGATGAACCACGGCAAACCCGCCGACACCGAGTTGCAACGGATGGTGCAATTAATTCAAACACGGAAT
CGGGAACGTGGTCCTGTGGCAATCTGA

Structures

Antitoxin

• AlphaFold DB: A0A0M2EZP0