Detailed information of TA system
Overview
TA module
| Type | IV | Classification (family/domain) | sdenTA/AbiEii(toxin) |
| Location | 4777842..4779282 | Replicon | chromosome |
| Accession | NZ_CP077421 | ||
| Organism | Pectobacterium polaris strain QK413-1 | ||
Toxin (Protein)
| Gene name | sdenT | Uniprot ID | - |
| Locus tag | KSL88_RS21390 | Protein ID | WP_205557395.1 |
| Coordinates | 4777842..4778729 (-) | Length | 296 a.a. |
Antitoxin (Protein)
| Gene name | sdenA | Uniprot ID | A0A7V8PRU9 |
| Locus tag | KSL88_RS21395 | Protein ID | WP_039474562.1 |
| Coordinates | 4778758..4779282 (-) | Length | 175 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| KSL88_RS21370 (KSL88_21325) | 4773835..4774656 | + | 822 | WP_014913737.1 | M55 family metallopeptidase | - |
| KSL88_RS21375 (KSL88_21330) | 4774716..4775663 | + | 948 | WP_224072774.1 | isoaspartyl peptidase/L-asparaginase | - |
| KSL88_RS21380 (KSL88_21335) | 4775876..4776784 | + | 909 | WP_174866951.1 | LysR family transcriptional regulator | - |
| KSL88_RS21385 (KSL88_21340) | 4776883..4777746 | + | 864 | WP_109225047.1 | YicC/YloC family endoribonuclease | - |
| KSL88_RS21390 (KSL88_21345) | 4777842..4778729 | - | 888 | WP_205557395.1 | nucleotidyl transferase AbiEii/AbiGii toxin family protein | Toxin |
| KSL88_RS21395 (KSL88_21350) | 4778758..4779282 | - | 525 | WP_039474562.1 | hypothetical protein | Antitoxin |
| KSL88_RS21400 (KSL88_21355) | 4779404..4779631 | + | 228 | Protein_4182 | DUF1732 domain-containing protein | - |
| KSL88_RS21405 (KSL88_21360) | 4779960..4780856 | + | 897 | WP_224072775.1 | hypothetical protein | - |
| KSL88_RS21410 (KSL88_21365) | 4780958..4781125 | + | 168 | WP_224072776.1 | hypothetical protein | - |
| KSL88_RS21415 (KSL88_21370) | 4781215..4781793 | + | 579 | WP_224072777.1 | BRO family protein | - |
| KSL88_RS21420 (KSL88_21375) | 4781951..4782268 | + | 318 | WP_224072778.1 | helix-turn-helix transcriptional regulator | - |
| KSL88_RS21425 (KSL88_21380) | 4782284..4782541 | - | 258 | WP_224072779.1 | helix-turn-helix transcriptional regulator | - |
| KSL88_RS21430 (KSL88_21385) | 4782639..4782989 | + | 351 | WP_224073909.1 | helix-turn-helix transcriptional regulator | - |
| KSL88_RS21435 (KSL88_21390) | 4783232..4783414 | + | 183 | WP_224072780.1 | hypothetical protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 296 a.a. Molecular weight: 33992.96 Da Isoelectric Point: 5.7136
>T207195 WP_205557395.1 NZ_CP077421:c4778729-4777842 [Pectobacterium polaris]
MLKQQIRQIVQSNPDYAAVTPVIEKEILHHDIMDVLIKQGVMQRLTFIGGTSLRMCYNSSRLSEDLDFNGGHDFKPSAFE
GLESEIQTYIQNKYETEVWVNKPSGEQQGDTVSWKISIVKEANRPDLPRQKMHIDVCAIPSFDIEKRPLINHYDIVVPTE
GILVPVQSLQETLADKLIALAYRARRIKPRDIWDIIWIKQRGIDLSKTLVEKKLTARQKQTEDFRQALSIQLAKLMSEDE
VRDDFNMEMSRFIPKPIKERTLDNPEYWAYVQGEVHAIASELLNDGAPKNPFDMG
MLKQQIRQIVQSNPDYAAVTPVIEKEILHHDIMDVLIKQGVMQRLTFIGGTSLRMCYNSSRLSEDLDFNGGHDFKPSAFE
GLESEIQTYIQNKYETEVWVNKPSGEQQGDTVSWKISIVKEANRPDLPRQKMHIDVCAIPSFDIEKRPLINHYDIVVPTE
GILVPVQSLQETLADKLIALAYRARRIKPRDIWDIIWIKQRGIDLSKTLVEKKLTARQKQTEDFRQALSIQLAKLMSEDE
VRDDFNMEMSRFIPKPIKERTLDNPEYWAYVQGEVHAIASELLNDGAPKNPFDMG
Download Length: 888 bp
>T207195 NZ_CP102932:c2958393-2958040 [Enterobacter sp. Crenshaw]
GTGTGGGCAATTAACACGACGGACAGGTTTGATCGCTGGTTCACTTCGCTTGACGATACCGATCGCGCCAGCGTACTTGC
AGCACTGCTTGTTTTGCGAGAGAAGGGGCCGGGTTTATCGAGACCCTACGCTGATACGCTTAAAGGCTCTCGTTACAGCA
ACATGAAAGAGCTACGTATTCAGAGTAAGGGCGATCCCTTGCGGGCGTTTTTCGCCTTTGATCCAAACCGCACGGGTATC
GTGCTTTGTGCGGGCAATAAGGTCGGCAATGAAAGGCGATTCTACGATGAGATGCTTCTCGTTGCTGACCGGGAATTCAC
TCACTGGCTGGATAGATTAAAAGAGAGGGAATAG
GTGTGGGCAATTAACACGACGGACAGGTTTGATCGCTGGTTCACTTCGCTTGACGATACCGATCGCGCCAGCGTACTTGC
AGCACTGCTTGTTTTGCGAGAGAAGGGGCCGGGTTTATCGAGACCCTACGCTGATACGCTTAAAGGCTCTCGTTACAGCA
ACATGAAAGAGCTACGTATTCAGAGTAAGGGCGATCCCTTGCGGGCGTTTTTCGCCTTTGATCCAAACCGCACGGGTATC
GTGCTTTGTGCGGGCAATAAGGTCGGCAATGAAAGGCGATTCTACGATGAGATGCTTCTCGTTGCTGACCGGGAATTCAC
TCACTGGCTGGATAGATTAAAAGAGAGGGAATAG
Antitoxin
Download Length: 175 a.a. Molecular weight: 19332.49 Da Isoelectric Point: 9.0504
>AT207195 WP_039474562.1 NZ_CP077421:c4779282-4778758 [Pectobacterium polaris]
MAKSDELLNALAKAVNAGGGIHSVTELAFMQGVPCDSAFRKFLADCVKKGLLRRVVKGFYESVITPPEPETAIYKIIKKL
RSGVLNYISLESQLSHTGDISQVVMGRVTVVTKGRSGCFDTPYGVIELTHTKKPVEQIAPNLYYDPDIKMYRAYKEQAIA
DLKHCQRNLHMLES
MAKSDELLNALAKAVNAGGGIHSVTELAFMQGVPCDSAFRKFLADCVKKGLLRRVVKGFYESVITPPEPETAIYKIIKKL
RSGVLNYISLESQLSHTGDISQVVMGRVTVVTKGRSGCFDTPYGVIELTHTKKPVEQIAPNLYYDPDIKMYRAYKEQAIA
DLKHCQRNLHMLES
Download Length: 525 bp
>AT207195 NZ_CP102932:c2958035-2957733 [Enterobacter sp. Crenshaw]
ATGGGAAGAACCCTTGAGCAGCTTATAGCGGATGAAAAGCCGGAGGTTGTCGCCAGCGCTCAGGCGATAGCAACGGATAT
TTTGCTCAACATTCATCTTGCTGAGTTACGCGAGAAAGTACAAAAAACGCAGGTAGAAATGGCGCAGGCGTTGGGTATCA
GGCAACCTACCGTTGCGGTAATGGAAAAGCCCGGGCGCGATTTGAAACTCTCTTCTCTCAAGCGCTACGTTGAGGCTGCG
GGCGGAAAGCTGCGGCTTGATGTGGAGCTGCCGGATGGCTCGCACTATGAGTTTGTGCTTTAG
ATGGGAAGAACCCTTGAGCAGCTTATAGCGGATGAAAAGCCGGAGGTTGTCGCCAGCGCTCAGGCGATAGCAACGGATAT
TTTGCTCAACATTCATCTTGCTGAGTTACGCGAGAAAGTACAAAAAACGCAGGTAGAAATGGCGCAGGCGTTGGGTATCA
GGCAACCTACCGTTGCGGTAATGGAAAAGCCCGGGCGCGATTTGAAACTCTCTTCTCTCAAGCGCTACGTTGAGGCTGCG
GGCGGAAAGCTGCGGCTTGATGTGGAGCTGCCGGATGGCTCGCACTATGAGTTTGTGCTTTAG
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|