Detailed information of TA system TA207192

Bioinformatically predicted

Overview

TA module

• Type: IV
• Classification (family/domain): cptAB/Cpta(toxin)
• Location: 4097422..4098082
• Replicon: chromosome
• Accession: NZ_CP077421
• Organism: Pectobacterium polaris strain QK413-1

Toxin (Protein)

• Gene name: cptA
• Uniprot ID: -
• Locus tag: KSL88_RS18285
• Protein ID: WP_174877124.1
• Coordinates: 4097422..4097835 (-)
• Length: 138 a.a.

Antitoxin (Protein)

• Gene name: cptB
• Uniprot ID: A0A093SCR9
• Locus tag: KSL88_RS18290
• Protein ID: WP_039487284.1
• Coordinates: 4097816..4098082 (-)
• Length: 89 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
KSL88_RS18260 (KSL88_18215)	4093197..4094519	+	1323	WP_095701619.1	MFS transporter	-
KSL88_RS18265 (KSL88_18220)	4094744..4095130	+	387	WP_039282122.1	thioesterase family protein	-
KSL88_RS18270 (KSL88_18225)	4095470..4095988	+	519	WP_224072541.1	flavodoxin FldB	-
KSL88_RS18275 (KSL88_18230)	4096017..4096340	+	324	WP_095993682.1	hypothetical protein	-
KSL88_RS18280 (KSL88_18235)	4096418..4097353	-	936	WP_109410759.1	23S rRNA (adenine(1618)-N(6))-methyltransferase RlmF	-
KSL88_RS18285 (KSL88_18240)	4097422..4097835	-	414	WP_174877124.1	protein YgfX	Toxin
KSL88_RS18290 (KSL88_18245)	4097816..4098082	-	267	WP_039487284.1	FAD assembly factor SdhE	Antitoxin
KSL88_RS18295 (KSL88_18250)	4098318..4099319	+	1002	WP_174868594.1	tRNA-modifying protein YgfZ	-
KSL88_RS18300 (KSL88_18255)	4099374..4100021	-	648	WP_039487281.1	hemolysin III family protein	-
KSL88_RS18305 (KSL88_18260)	4100422..4101030	+	609	WP_095701613.1	HD domain-containing protein	-
KSL88_RS18310 (KSL88_18265)	4101085..4102089	+	1005	WP_174871919.1	substrate-binding domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Inner membrane protein YgfX (2-132)

Antitoxin

• Flavinator of succinate dehydrogenase (8-79)

Sequences

Toxin

Protein

• Length: 138 a.a.
• Molecular weight: 16325.33 Da
• Isoelectric Point: 10.8947

>T207192 WP_174877124.1 NZ_CP077421:c4097835-4097422 [Pectobacterium polaris]
VAQWQCDLRVSWRMQLLSLVVHGLLVLLILLAPWPDGYAWLWLCLVTMVMFGFIRSQKNIKSRQGEIVLLSETTLNWRRQ
EWQIVKRPWLLKNGVLLSLRAVNGKDKQQLWLASDSMGDEEWRHLRQLLLQQKHWAR

Nucleotide

• Length: 414 bp

>T207192 NZ_CP102932:c1049265-1049047 [Enterobacter sp. Crenshaw]
ATGTCTGATAAACCACTCACAAAAATCGATTATTTGATGCGCTTACGACGTTGTCAGTCAATTGACACGCTTGAGCGCGT
CATTGAAAAGAATAAATACGAGCTTTCTGATAATGAGCTGGCGGTATTTTATTCAGCCGCTGACCATCGTCTTGCTGAAC
TGACAATGAATAAGCTGTATGACAAAATCCCTACTTCTGTGTGGAAATTTGTCCGTTAA

Antitoxin

Protein

• Length: 89 a.a.
• Molecular weight: 10489.90 Da
• Isoelectric Point: 5.1392

>AT207192 WP_039487284.1 NZ_CP077421:c4098082-4097816 [Pectobacterium polaris]
MEIDNKSRIHWACRRGMRELDIAIMPFFEHDYDTLNDTDKRTFVRLLQSDDPDLFNWLMNHGEPEDGELKRIISLIQTRN
KDRGPVAM

Nucleotide

• Length: 267 bp

>AT207192 NZ_CP102932:c1049667-1049293 [Enterobacter sp. Crenshaw]
ATGGACGAGTACTCGCCAAAAAGGCATGATATCGCGCAGTTGAAATTTCTCTGCGAATCCTTGTACCATGACTGCCTTGC
CAATCTTGATGAAAGTAACCATGGCTGGGTAAACGACCCAACGTCTGCCATCAATTTACAGTTGAATGAGCTGATAGAGC
ATATCGCAACCTTCGCACTTAATTATAAAATTAAGTACAATGAAGATAATAAGCTCATTGAGCAAATTGATGAATACCTG
GACGACACCTTTATGTTGTTCAGCAGTTACGGCATTAACGCTCAGGATTTGCAAAAATGGCGTAAATCGGGAAATCGGCT
ATTCCGCTGTTTCGTCAACGTGAGCAGAGCTAACCCGGTGAGTCTTTCCTGTTAA

Structures

Antitoxin

• AlphaFold DB: A0A093SCR9