Detailed information of TA system TA207189

Bioinformatically predicted

Overview

TA module

• Type: VII
• Classification (family/domain): HepT-MntA/HepT(toxin)
• Location: 3290170..3290969
• Replicon: chromosome
• Accession: NZ_CP077421
• Organism: Pectobacterium polaris strain QK413-1

Toxin (Protein)

• Gene name: hepT
• Uniprot ID: -
• Locus tag: KSL88_RS14795
• Protein ID: WP_095698920.1
• Coordinates: 3290550..3290969 (+)
• Length: 140 a.a.

Antitoxin (Protein)

• Gene name: mntA
• Uniprot ID: A0A6P1S5H0
• Locus tag: KSL88_RS14790
• Protein ID: WP_039482638.1
• Coordinates: 3290170..3290553 (+)
• Length: 128 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
KSL88_RS14775 (KSL88_14725)	3285352..3286488	-	1137	WP_095698924.1	polysaccharide export protein	-
KSL88_RS14780 (KSL88_14730)	3286614..3287693	-	1080	WP_224072241.1	UDP-N-acetylglucosamine--undecaprenyl-phosphate N-acetylglucosaminephosphotransferase	-
KSL88_RS14785 (KSL88_14735)	3288444..3290030	+	1587	WP_224072242.1	TerC family protein	-
KSL88_RS14790 (KSL88_14740)	3290170..3290553	+	384	WP_039482638.1	nucleotidyltransferase domain-containing protein	Antitoxin
KSL88_RS14795 (KSL88_14745)	3290550..3290969	+	420	WP_095698920.1	DUF86 domain-containing protein	Toxin
KSL88_RS14800 (KSL88_14750)	3291013..3292365	-	1353	WP_095698919.1	anaerobic C4-dicarboxylate transporter DcuC	-
KSL88_RS14805 (KSL88_14755)	3292629..3294464	-	1836	WP_224072243.1	outer membrane assembly protein AsmA	-
KSL88_RS14810 (KSL88_14760)	3294527..3295108	-	582	WP_039482649.1	dCTP deaminase	-
KSL88_RS14815 (KSL88_14765)	3295216..3295857	-	642	WP_010281304.1	uridine kinase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Ribonuclease HepT-like (12-129)

Antitoxin

• Polymerase beta, nucleotidyltransferase (4-93)

Sequences

Toxin

Protein

• Length: 140 a.a.
• Molecular weight: 16129.50 Da
• Isoelectric Point: 7.3229

>T207189 WP_095698920.1 NZ_CP077421:3290550-3290969 [Pectobacterium polaris]
MTDILLNKSSTIQRCLRRIREEFDTKEEFRQNFTKQDSVILNIQRACEAAIDIANYLIRIKQLGIPQSSRDSFALLAANQ
IITIDLSDNLQKMVGLRNIAVHDYQALNLDIVIHVISHRLSDFERFIKEVARYSDSQHL

Nucleotide

• Length: 420 bp

>T207189 NZ_CP102932:c257959-257672 [Enterobacter sp. Crenshaw]
ATGCATAAATTAACACCCTACGATCCAGCCAATGCGCTGGTGGATGACGAGGAAATCGCCGTGTTTATGGCTGATGCCTT
AGAAACGGGCGACTCAGCGTATATTGCTAAAGCGCTGGGCGTCATCGCGCGCGCGAAAGGAATGTCGACCATTTCACAGC
AAACTGGCCTATCACGAGAGCAACTGTATCGATCGTTCAGTGATAAAGGAAACCCAACGCTTAAAACCACTCTGGCGGTC
ATGAAAGCATTGGGTCTTGGGCTAACAATCAAACACGCTGGAGATTAA

Antitoxin

Protein

• Length: 128 a.a.
• Molecular weight: 14312.49 Da
• Isoelectric Point: 5.2241

>AT207189 WP_039482638.1 NZ_CP077421:3290170-3290553 [Pectobacterium polaris]
MFDKIVSTLKKQIPDIKIIYLFGSQATGNARADSDVDIAILATRALDPVERWELSNQLAKEVGRDVDLIDLLQASTVLKM
EIVRNGKLLYDAKAAAGEFEMTTLSMYQHLQRERADIIRSFNQDLKA

Nucleotide

• Length: 384 bp

>AT207189 NZ_CP102932:c258268-257966 [Enterobacter sp. Crenshaw]
ATGAAGGAGATCGTTCAGACAGAATCCTTCCAACGCTGGGAGCAAAACTTAAAAGATCGGCGAGCGAAGACCATTATCGC
TTCCCGCCTCTTTCGGTTGGCAAATGGTTTAGCGGGCGACATTAAACCCGTTGGGGAAGGTATAAGTGAGCTGAGGATCC
ACTATGGTCCGGGCTACAGACTCTATTTTAAAGACCAGGGCAATTGCATCATCGTGCTGTTGTGTGGTGGTGACAAAAGC
AGCCAGGCCAGAGACATACTTATGGCAAAAATGCTGAGCAATGTATCCCAATGGCAGGAGTGA

Structures

Antitoxin

• AlphaFold DB: A0A6P1S5H0