Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | vagCD/VapC-VagC |
| Location | 849646..850286 | Replicon | chromosome |
| Accession | NZ_CP077421 | ||
| Organism | Pectobacterium polaris strain QK413-1 | ||
Toxin (Protein)
| Gene name | vagD | Uniprot ID | - |
| Locus tag | KSL88_RS03730 | Protein ID | WP_224073155.1 |
| Coordinates | 849870..850286 (+) | Length | 139 a.a. |
Antitoxin (Protein)
| Gene name | vagC | Uniprot ID | Q6D0W2 |
| Locus tag | KSL88_RS03725 | Protein ID | WP_011095187.1 |
| Coordinates | 849646..849873 (+) | Length | 76 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| KSL88_RS03715 (KSL88_03715) | 845246..848080 | + | 2835 | WP_224073153.1 | excinuclease ABC subunit UvrA | - |
| KSL88_RS03720 (KSL88_03720) | 848096..848515 | + | 420 | WP_224073154.1 | secondary thiamine-phosphate synthase enzyme YjbQ | - |
| KSL88_RS03725 (KSL88_03725) | 849646..849873 | + | 228 | WP_011095187.1 | type II toxin-antitoxin system VapB family antitoxin | Antitoxin |
| KSL88_RS03730 (KSL88_03730) | 849870..850286 | + | 417 | WP_224073155.1 | type II toxin-antitoxin system VapC family toxin | Toxin |
| KSL88_RS03735 (KSL88_03735) | 850911..851465 | - | 555 | WP_224073156.1 | type I-F CRISPR-associated endoribonuclease Cas6/Csy4 | - |
| KSL88_RS03740 (KSL88_03740) | 851475..852485 | - | 1011 | WP_224073157.1 | type I-F CRISPR-associated protein Csy3 | - |
| KSL88_RS03745 (KSL88_03745) | 852499..853431 | - | 933 | WP_224073158.1 | type I-F CRISPR-associated protein Csy2 | - |
| KSL88_RS03750 (KSL88_03750) | 853428..854762 | - | 1335 | WP_224073159.1 | type I-F CRISPR-associated protein Csy1 | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 139 a.a. Molecular weight: 15251.79 Da Isoelectric Point: 8.7768
>T207187 WP_224073155.1 NZ_CP077421:849870-850286 [Pectobacterium polaris]
VSRLFMLDTNICSFIMREHPTAMIDKLQQCTLRRDRIVVSAITYAEMRFGAVGKKASPRHMQLVDAFCRRLDAVLPWDSA
AVDATTKIKIALAAAGTPIGPNDTAIAGHAISVKAILVTNNLREFERVQGLTLEDWVN
VSRLFMLDTNICSFIMREHPTAMIDKLQQCTLRRDRIVVSAITYAEMRFGAVGKKASPRHMQLVDAFCRRLDAVLPWDSA
AVDATTKIKIALAAAGTPIGPNDTAIAGHAISVKAILVTNNLREFERVQGLTLEDWVN
Download Length: 417 bp
>T207187 NZ_CP102929:c6845492-6844917 [Pseudomonas sp. CBS]
ATGGACATCGAAAAACTCAAGGGCCGCCTCGACTTCCTGCGCGAAGCGGAAAAACTCAAGGACGTGCTCAGAAGCGCGCA
CACCTCTTCCGGCCGCACCGAAAGCACCGCGGAACACAGCTGGCGCCTGTGCCTGATGGCAATTACCTTCGGGGATGAAC
TGGCCGGCCTCGACCTGCTGAAAATCCTCAAGATGTGCGTAATCCACGACCTGGGAGAGGCCCTCCACGGCGACATCCCG
GCGGTCCAGCAAGCGCAGTTCCCCAACAAGAGCCAGCAAGAACACGACGACCTGCTGTTGCTGACCCGAGCACTGGATGA
GCCGTTGCGGGTCGAGATTCTGGCCCTGTGGGACGACTACGAAAACGCCCGGTCCGCCGAGGCCAAGGCAGTCAAAGCCC
TGGACAAACTGGAGACCCTGCTGCAACACAACCAGGGCCTGAACCCGCCCGACTTCGACTACGCCTTCAATCTGGCCTAT
GGCAAGAAACACACCAGCGCCGAGCCGATTTTCCAGACACTGCGCGAGATCATCGACCAGGATACAGAAGCAAAAATCCA
GACTCCCAACCGGTAG
ATGGACATCGAAAAACTCAAGGGCCGCCTCGACTTCCTGCGCGAAGCGGAAAAACTCAAGGACGTGCTCAGAAGCGCGCA
CACCTCTTCCGGCCGCACCGAAAGCACCGCGGAACACAGCTGGCGCCTGTGCCTGATGGCAATTACCTTCGGGGATGAAC
TGGCCGGCCTCGACCTGCTGAAAATCCTCAAGATGTGCGTAATCCACGACCTGGGAGAGGCCCTCCACGGCGACATCCCG
GCGGTCCAGCAAGCGCAGTTCCCCAACAAGAGCCAGCAAGAACACGACGACCTGCTGTTGCTGACCCGAGCACTGGATGA
GCCGTTGCGGGTCGAGATTCTGGCCCTGTGGGACGACTACGAAAACGCCCGGTCCGCCGAGGCCAAGGCAGTCAAAGCCC
TGGACAAACTGGAGACCCTGCTGCAACACAACCAGGGCCTGAACCCGCCCGACTTCGACTACGCCTTCAATCTGGCCTAT
GGCAAGAAACACACCAGCGCCGAGCCGATTTTCCAGACACTGCGCGAGATCATCGACCAGGATACAGAAGCAAAAATCCA
GACTCCCAACCGGTAG
Antitoxin
Download Length: 76 a.a. Molecular weight: 8894.05 Da Isoelectric Point: 4.5216
>AT207187 WP_011095187.1 NZ_CP077421:849646-849873 [Pectobacterium polaris]
MRIVSVFKNGNNRAIRLPRDMDFEGVNELEIVREGDTIMLRPVKPNWHSFLQEERADADFMTERQDVVEEGRFEL
MRIVSVFKNGNNRAIRLPRDMDFEGVNELEIVREGDTIMLRPVKPNWHSFLQEERADADFMTERQDVVEEGRFEL
Download Length: 228 bp
>AT207187 NZ_CP102929:c6846137-6845580 [Pseudomonas sp. CBS]
ATGTCCGACCTGTTGCTCAAGCCTGCCCTGCCCGGCATTGCGCTGAGACGATGGCGTCTGCTGCACCGCGTCAAACAGAC
TCACGCCGCCGAGTTGTTCCACGTCACCCAGTCGACGATTTCCCGCTGGGAAAGTGGCGTGCAGGCCATGGAGCCTGCGG
CGCACCGACAACTTGAACAGTTGCTGGCCGCACGCCTGGAAGCCGCCGCCGATCAGGCCCTCGCCCGGCTGGTCAAGGAA
AGCCCGCGCCCGATGCACCTGGTGTGTGACCTGACCCACCGTCTGCTGGCTTGCTCGGCCTCCCGTGCCGCCGAGTTCAG
CAGCCCGTTGGCGGAACTTCTGGGGCATTCACTGTGGCGCTTCGTGACGCCGGAAATCCTGCGTATGGAGTCCGCGCTGG
ATGACTCGGGCTGGCGCGACAGCCTCGCCCCACCGGCCCTGGAGTTCATCACCGGCACCAACGACTCCACGGTTGTACCG
ATCCGCCAGAGCCTGTGCCGCTGGACCCGCATCCCGCTGAGCGATGGCACCGCCGCGCGGCTGGTCGAGACGCTCTAA
ATGTCCGACCTGTTGCTCAAGCCTGCCCTGCCCGGCATTGCGCTGAGACGATGGCGTCTGCTGCACCGCGTCAAACAGAC
TCACGCCGCCGAGTTGTTCCACGTCACCCAGTCGACGATTTCCCGCTGGGAAAGTGGCGTGCAGGCCATGGAGCCTGCGG
CGCACCGACAACTTGAACAGTTGCTGGCCGCACGCCTGGAAGCCGCCGCCGATCAGGCCCTCGCCCGGCTGGTCAAGGAA
AGCCCGCGCCCGATGCACCTGGTGTGTGACCTGACCCACCGTCTGCTGGCTTGCTCGGCCTCCCGTGCCGCCGAGTTCAG
CAGCCCGTTGGCGGAACTTCTGGGGCATTCACTGTGGCGCTTCGTGACGCCGGAAATCCTGCGTATGGAGTCCGCGCTGG
ATGACTCGGGCTGGCGCGACAGCCTCGCCCCACCGGCCCTGGAGTTCATCACCGGCACCAACGACTCCACGGTTGTACCG
ATCCGCCAGAGCCTGTGCCGCTGGACCCGCATCCCGCTGAGCGATGGCACCGCCGCGCGGCTGGTCGAGACGCTCTAA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|