Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-DnaT
Location 2883260..2883782 Replicon chromosome
Accession NZ_CP077405
Organism Citrobacter braakii strain FDAARGOS 1421

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag I6L51_RS14330 Protein ID WP_080858538.1
Coordinates 2883501..2883782 (+) Length 94 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag I6L51_RS14325 Protein ID WP_080858539.1
Coordinates 2883260..2883511 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
I6L51_RS14295 (I6L51_14295) 2879531..2879920 - 390 WP_080858545.1 antiterminator Q family protein -
I6L51_RS14300 (I6L51_14300) 2879923..2880219 - 297 WP_080858544.1 hypothetical protein -
I6L51_RS14305 (I6L51_14305) 2880216..2880818 - 603 WP_080858543.1 DUF1367 family protein -
I6L51_RS14310 (I6L51_14310) 2880882..2881460 - 579 WP_080858542.1 Rha family transcriptional regulator -
I6L51_RS14315 (I6L51_14315) 2881985..2882314 + 330 WP_080858541.1 hypothetical protein -
I6L51_RS14320 (I6L51_14320) 2882311..2883111 - 801 WP_080858540.1 hypothetical protein -
I6L51_RS14325 (I6L51_14325) 2883260..2883511 + 252 WP_080858539.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
I6L51_RS14330 (I6L51_14330) 2883501..2883782 + 282 WP_080858538.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
I6L51_RS14335 (I6L51_14335) 2883876..2884193 + 318 WP_080858801.1 DNA-binding transcriptional regulator -
I6L51_RS14340 (I6L51_14340) 2884280..2884792 - 513 WP_080858537.1 GNAT family N-acetyltransferase -
I6L51_RS14345 (I6L51_14345) 2884975..2885211 - 237 WP_023222359.1 hypothetical protein -
I6L51_RS14350 (I6L51_14350) 2885225..2885563 - 339 WP_080858536.1 hypothetical protein -
I6L51_RS14355 (I6L51_14355) 2885560..2886303 - 744 WP_080858535.1 DUF1627 domain-containing protein -
I6L51_RS14360 (I6L51_14360) 2886323..2887069 - 747 WP_080858534.1 ATP-binding protein -
I6L51_RS27235 2887076..2887996 - 921 WP_249025114.1 DUF1376 domain-containing protein -
I6L51_RS14370 (I6L51_14370) 2888312..2888536 + 225 WP_143329686.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - gtrB 2836629..2902227 65598


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-84)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 11088.92 Da        Isoelectric Point: 10.4563

>T207141 WP_080858538.1 NZ_CP077405:2883501-2883782 [Citrobacter braakii]
MTYELKFERRAKKEWDKLGHPVREQFKKKLAERLENPHIPSARLHGRPNRYKIKLRSSGYRLVYDVIDDKLVLLVIVIGK
RAGNEVYELADER

Download         Length: 282 bp

>T207141 NZ_CP102895:c10417-9887 [Klebsiella quasipneumoniae]
ATGGACGGTTTAAGGATTGAGATTTTTTCAGAGGAAGTTGAATATCAATTAAGCAACTTCGATTGTGGAGAAGAGTATCT
GAATACTTTTCTCACCGATCATCTGCAACGTCAGCACAGTAGTAAGATTTTACGGGGTTATCTGCTCGTGACGAGAGAGG
ATAGACCACGTGTCATGGGGTACTACACCCTGTCAGGCAGTTGCTTTGAGAAAATACTTCTCCCCAGCAAAACACAACAA
AAGCGTGTGCCCTACAAAAATGTGCCGAGCGTGACTTTGGGCCGTCTGGCAATTGATAAAAGCATTCATCACCAGGGATA
TGGAGAAACACTTGTTACCCATGCGATGAAAGTCGTGTATCAGGCCTCGCAGGCTGTGGGTATACACGGAATGTTCGTGG
AGGCGCTGAACGATAACGCCAAAAAATTCTACCTTCGACTGGGTTTTATACAGTTAAAGGAAGAAAACTGTGATTCGCTC
TTCTACCCGACAAAATCTATTGAAGTATTGTTCGAAGTAAATGACGAATAA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9151.31 Da        Isoelectric Point: 3.7425

>AT207141 WP_080858539.1 NZ_CP077405:2883260-2883511 [Citrobacter braakii]
MTYQILTTIAASITDLKRNPMGTVADGEGNAVAILNRNEPAFYCVPPELYAYYIELAEDAELNAIADERMKDPDIVSVNL
DDL

Download         Length: 252 bp

>AT207141 NZ_CP102895:c10690-10421 [Klebsiella quasipneumoniae]
ATGTCAGCACTGAAGAAGCAGCGCATCGATCTGAGATTAAATGAAGACGACAAACACATGATCGAAGAAGCTGCAGCAAT
GACTAACCAGTCCATTTCGCAGTTCATGGTCAGTACCGCCTCAGCACGTGCTGCTGAAGTTATTGATCAGCACCGTCGCC
TGCTCCTCAATGAGGAGTCCTGGAATCTGGTTATGGATGCAATCACTAATCCGCCAGCACCAAATGACCGGCTGAAACGC
GCCACTAACCGTCTCCGGGAACTGGAGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References