Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | EcnAB/- |
Location | 4656258..4656621 | Replicon | chromosome |
Accession | NC_003902 | ||
Organism | Xanthomonas campestris pv. campestris str. ATCC 33913 |
Toxin (Protein)
Gene name | EcnB | Uniprot ID | G0CKD4 |
Locus tag | XCC_RS20340 | Protein ID | WP_011270059.1 |
Coordinates | 4656258..4656392 (-) | Length | 45 a.a. |
Antitoxin (Protein)
Gene name | EcnA | Uniprot ID | Q8P3Z2 |
Locus tag | XCC_RS20345 | Protein ID | WP_011038999.1 |
Coordinates | 4656469..4656621 (-) | Length | 51 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
XCC_RS20320 | 4651522..4653174 | - | 1653 | WP_043877841.1 | M28 family peptidase | - |
XCC_RS20325 | 4653339..4654283 | - | 945 | WP_043877842.1 | MBL fold metallo-hydrolase | - |
XCC_RS20330 | 4654367..4655656 | - | 1290 | WP_029629069.1 | tryptophan--tRNA ligase | - |
XCC_RS20335 | 4655816..4656025 | - | 210 | WP_011038998.1 | CsbD family protein | - |
XCC_RS20340 | 4656258..4656392 | - | 135 | WP_011270059.1 | entericidin A/B family lipoprotein | Toxin |
XCC_RS20345 | 4656469..4656621 | - | 153 | WP_011038999.1 | entericidin A/B family lipoprotein | Antitoxin |
XCC_RS20350 | 4656732..4657655 | - | 924 | WP_011039000.1 | arginase | - |
XCC_RS20355 | 4657969..4658430 | + | 462 | WP_011039001.1 | roadblock/LC7 domain-containing protein | - |
XCC_RS20360 | 4658513..4658872 | + | 360 | WP_011039002.1 | hypothetical protein | - |
XCC_RS20365 | 4658975..4659892 | + | 918 | WP_011039003.1 | hypothetical protein | - |
XCC_RS20370 | 4659889..4660431 | + | 543 | WP_011039004.1 | GTPase | - |
XCC_RS20375 | 4660766..4661449 | + | 684 | WP_011039005.1 | dTMP kinase | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 45 a.a. Molecular weight: 4431.27 Da Isoelectric Point: 9.3487
>T20714 WP_011270059.1 NC_003902:c4656392-4656258 [Xanthomonas campestris pv. campestris str. ATCC 33913]
MKRAIALLVLSMLSVGMLAGCNTVAGAGKDVQGAGEKVEDAARK
MKRAIALLVLSMLSVGMLAGCNTVAGAGKDVQGAGEKVEDAARK
Download Length: 135 bp
>T20714 NC_003902:c4656392-4656258 [Xanthomonas campestris pv. campestris str. ATCC 33913]
ATGAAGCGTGCAATTGCATTGTTGGTGCTGTCGATGTTGTCGGTTGGAATGCTGGCGGGTTGCAACACCGTCGCAGGTGC
CGGCAAGGACGTGCAGGGCGCTGGCGAGAAGGTGGAAGACGCCGCGCGCAAGTGA
ATGAAGCGTGCAATTGCATTGTTGGTGCTGTCGATGTTGTCGGTTGGAATGCTGGCGGGTTGCAACACCGTCGCAGGTGC
CGGCAAGGACGTGCAGGGCGCTGGCGAGAAGGTGGAAGACGCCGCGCGCAAGTGA
Antitoxin
Download Length: 51 a.a. Molecular weight: 5173.15 Da Isoelectric Point: 8.2782
>AT20714 WP_011038999.1 NC_003902:c4656621-4656469 [Xanthomonas campestris pv. campestris str. ATCC 33913]
MKRLLTLMVLGLFSAGMMTGCNTMAGAGKDMQGAGDKVEKTADKCSDGKC
MKRLLTLMVLGLFSAGMMTGCNTMAGAGKDMQGAGDKVEKTADKCSDGKC
Download Length: 153 bp
>AT20714 NC_003902:c4656621-4656469 [Xanthomonas campestris pv. campestris str. ATCC 33913]
ATGAAGCGACTGCTGACACTGATGGTGCTGGGCCTGTTCTCGGCCGGCATGATGACTGGCTGTAACACCATGGCTGGTGC
CGGAAAGGACATGCAGGGTGCGGGTGACAAGGTCGAGAAGACCGCCGACAAATGCAGCGACGGTAAGTGCTAA
ATGAAGCGACTGCTGACACTGATGGTGCTGGGCCTGTTCTCGGCCGGCATGATGACTGGCTGTAACACCATGGCTGGTGC
CGGAAAGGACATGCAGGGTGCGGGTGACAAGGTCGAGAAGACCGCCGACAAATGCAGCGACGGTAAGTGCTAA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Structures
Toxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A0H2XDQ0 |
Antitoxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | Q8P3Z2 |