Detailed information of TA system TA020713

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): tacAT/DUF1778(antitoxin)
• Location: 3678429..3679207
• Replicon: chromosome
• Accession: NC_003902
• Organism: Xanthomonas campestris pv. campestris str. ATCC 33913

Toxin (Protein)

• Gene name: TacT2
• Uniprot ID: Q8P667
• Locus tag: XCC_RS16110
• Protein ID: WP_011038220.1
• Coordinates: 3678716..3679207 (+)
• Length: 164 a.a.

Antitoxin (Protein)

• Gene name: TacA2
• Uniprot ID: Q8P668
• Locus tag: XCC_RS16105
• Protein ID: WP_011038219.1
• Coordinates: 3678429..3678719 (+)
• Length: 97 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
XCC_RS16080	3673891..3674331	-	441	WP_011038214.1	pilin	-
XCC_RS16085	3674658..3675914	+	1257	WP_011038215.1	type II secretion system F family protein	-
XCC_RS16090	3675921..3676784	+	864	WP_011038216.1	A24 family peptidase	-
XCC_RS16095	3676798..3677421	+	624	WP_011038217.1	dephospho-CoA kinase	-
XCC_RS16100	3677953..3678354	+	402	WP_019237348.1	type I toxin-antitoxin system SymE family toxin	-
XCC_RS16105	3678429..3678719	+	291	WP_011038219.1	DUF1778 domain-containing protein	Antitoxin
XCC_RS16110	3678716..3679207	+	492	WP_011038220.1	GNAT family N-acetyltransferase	Toxin
XCC_RS16115	3679350..3680684	-	1335	WP_019237347.1	HAMP domain-containing histidine kinase	-
XCC_RS16120	3680677..3681354	-	678	WP_003490678.1	response regulator transcription factor	-
XCC_RS16125	3682004..3682879	-	876	WP_011038222.1	30S ribosomal protein S6--L-glutamate ligase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• GNAT domain (42-144)

Antitoxin

• Vibrio phage ICP1, Orf50 (1-95)

Sequences

Toxin

Protein

• Length: 164 a.a.
• Molecular weight: 17638.31 Da
• Isoelectric Point: 8.1192

>T20713 WP_011038220.1 NC_003902:3678716-3679207 [Xanthomonas campestris pv. campestris str. ATCC 33913]
MTVSAPEPLTAHHRVEPFASGVESLDHWLKRRALKNQATGASRTFVACEDDRVVAYYALASSAVAVDATPGRFRRNMPDP
IPVVVLGRLAVDQSLHGRGFGRALMQDAGKRILHAADTIGIRGLLVHALSADAKAFYERIGFEPSPLDPMVLVVTLEDLK
ASL

Nucleotide

• Length: 492 bp

>T20713 NC_003902:3678716-3679207 [Xanthomonas campestris pv. campestris str. ATCC 33913]
ATGACGGTATCGGCGCCGGAACCGCTGACAGCGCATCACCGGGTCGAACCGTTCGCATCGGGCGTGGAGAGCCTGGATCA
CTGGCTCAAGCGCCGCGCCCTGAAAAATCAGGCAACCGGTGCGTCACGGACCTTCGTTGCCTGCGAGGATGACCGCGTGG
TGGCCTATTACGCCCTGGCGTCGAGTGCGGTCGCCGTGGACGCGACGCCCGGCCGCTTCCGTCGCAACATGCCGGACCCG
ATCCCCGTGGTGGTGCTTGGGAGGCTTGCTGTTGACCAATCCCTGCATGGCAGAGGTTTTGGCCGCGCCCTGATGCAGGA
TGCTGGCAAGCGCATCTTGCATGCGGCCGACACCATCGGCATTCGCGGGCTGCTCGTGCATGCGCTCTCGGCGGACGCCA
AGGCGTTTTACGAGCGCATCGGCTTCGAACCTTCCCCGCTGGATCCCATGGTGCTGGTCGTCACGCTGGAAGACCTGAAA
GCCAGTCTGTGA

Antitoxin

Protein

• Length: 97 a.a.
• Molecular weight: 10678.23 Da
• Isoelectric Point: 10.5480

>AT20713 WP_011038219.1 NC_003902:3678429-3678719 [Xanthomonas campestris pv. campestris str. ATCC 33913]
MSTPNTTPGKRETLNLRIKPEERSLIDRAAKARGKNRTDFMLDAARSAAEEALLDQTLITASPDAYAAFLARLDMPPQPN
ARLRKTMQTPAPWEKA

Nucleotide

• Length: 291 bp

>AT20713 NC_003902:3678429-3678719 [Xanthomonas campestris pv. campestris str. ATCC 33913]
ATGTCCACACCCAACACTACGCCTGGCAAGCGCGAAACCTTGAATCTCCGCATCAAGCCGGAGGAGCGCAGCCTGATCGA
CCGGGCCGCCAAGGCGCGCGGGAAGAACCGCACCGATTTCATGCTGGACGCAGCGCGCTCGGCGGCCGAGGAAGCCTTGC
TGGACCAGACCCTCATCACGGCCAGCCCGGACGCCTACGCCGCCTTTTTGGCACGGCTGGACATGCCGCCGCAGCCGAAC
GCGCGCCTGCGCAAGACGATGCAGACGCCCGCTCCTTGGGAGAAGGCATGA

Structures

Toxin

• AlphaFold DB: Q8P667

Antitoxin

• AlphaFold DB: Q8P668