Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-RelB
Location 67610..68136 Replicon plasmid unnamed1
Accession NZ_CP077367
Organism Pantoea agglomerans strain FDAARGOS 1447

Toxin (Protein)


Gene name relE Uniprot ID A0A8X8J030
Locus tag I6L77_RS18795 Protein ID WP_010257030.1
Coordinates 67610..67897 (-) Length 96 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag I6L77_RS18800 Protein ID WP_062759514.1
Coordinates 67897..68136 (-) Length 80 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
I6L77_RS18770 (I6L77_18765) 63698..64723 - 1026 WP_062759517.1 alpha/beta hydrolase -
I6L77_RS18775 (I6L77_18770) 64792..65916 - 1125 WP_081114162.1 MFS transporter -
I6L77_RS18780 (I6L77_18775) 66119..67015 + 897 WP_062759515.1 LysR family transcriptional regulator -
I6L77_RS18785 (I6L77_18780) 67079..67255 - 177 WP_010257023.1 KGG domain-containing protein -
I6L77_RS18790 (I6L77_18785) 67380..67565 + 186 WP_245006275.1 hypothetical protein -
I6L77_RS18795 (I6L77_18790) 67610..67897 - 288 WP_010257030.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
I6L77_RS18800 (I6L77_18795) 67897..68136 - 240 WP_062759514.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
I6L77_RS18805 (I6L77_18800) 68496..70469 + 1974 WP_062759513.1 methyl-accepting chemotaxis protein -
I6L77_RS18810 (I6L77_18805) 70574..71590 + 1017 WP_010257039.1 NAD(P)-dependent alcohol dehydrogenase -
I6L77_RS18815 (I6L77_18810) 71640..72308 - 669 WP_062759512.1 DUF2268 domain-containing putative Zn-dependent protease -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Mobilizable plasmid - - 1..180597 180597


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-83)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(2-79)


Sequences

Toxin        


Download         Length: 96 a.a.        Molecular weight: 11058.91 Da        Isoelectric Point: 10.3173

>T207087 WP_010257030.1 NZ_CP077367:c67897-67610 [Pantoea agglomerans]
MTWQLEFDQRALKEWRKLGPTVREQLKKKLAECLESPRIEANKLSGIPDCYKIKLKSSGYRLVYQVIDDRVVVFVVAVGK
RERSEVYSAASRRLS

Download         Length: 288 bp

>T207087 NZ_CP102877:c5242910-5242527 [Klebsiella pneumoniae]
ATGACCTCCGGATCTGCGCTTTTTGATACCAATATTCTTATTGATTTATTTAGCGGGCGTCGCGAAGCCAAACAGGCGCT
GGAGGCCTGGCCACCGCAGAATGCGATCAGTCTGATTACCTGGATGGAGGTGATGGTTGGCGCTAAAAAATATCACCAGG
AGCAGCGCACGCGAATGGCGCTGAGCACCTTTAATATCATTAACATCTCACAGGATATTGCAGAGCGAAGCGTTGCGCTG
CGGCAGGAGTATAAGCTTAAGCTGCCGGATGCCATCATTCTGGCGACGGCGCAACTCCATCGTCTGGAACTAATTACGCG
GAATACGAAGGATTTTACCGGTATTCCTGGCGTAGTCACGCCGTACGAAATCCACCCTGAATAA

Antitoxin


Download         Length: 80 a.a.        Molecular weight: 9051.40 Da        Isoelectric Point: 4.3410

>AT207087 WP_062759514.1 NZ_CP077367:c68136-67897 [Pantoea agglomerans]
MGTINIRIDDDLKTRSYAALEKMGVTPSDALRLMLEYIADNERLPFKQTLLSDEDAALVDIVKERLRYPEPVRVTLDDL

Download         Length: 240 bp

>AT207087 NZ_CP102877:c5243152-5242910 [Klebsiella pneumoniae]
ATGATGGCTGAAAGGGATATGGGCAGAATTCTTCTCGATTTATCAGACGATGTCATTCAACGTCTCGATGACCTCAAAGT
GCAGCGTAACATTCCGCGAGCGGAACTGTTACGTGAAGCGGTTGAACAATATCTGGAGAAACAAGATCGAGCTAAAGATA
CCATCTCCAGTGCGCTGGGTCTGTGGCAAGACTGCGAAGAAGACGGCATGGAATATCAACGTCAGCTACGCAAGGAGTGG
TAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References