Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | /RES-TIGR02293 |
| Location | 2825923..2826839 | Replicon | chromosome |
| Accession | NZ_CP077317 | ||
| Organism | Providencia rettgeri strain FDAARGOS 1450 | ||
Toxin (Protein)
| Gene name | - | Uniprot ID | - |
| Locus tag | I6L80_RS12800 | Protein ID | WP_217007720.1 |
| Coordinates | 2826381..2826839 (+) | Length | 153 a.a. |
Antitoxin (Protein)
| Gene name | - | Uniprot ID | A0A6G6PJY5 |
| Locus tag | I6L80_RS12795 | Protein ID | WP_004910826.1 |
| Coordinates | 2825923..2826384 (+) | Length | 154 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| I6L80_RS12765 (I6L80_12765) | 2821359..2821832 | - | 474 | WP_109912202.1 | NUDIX domain-containing protein | - |
| I6L80_RS12770 (I6L80_12770) | 2822123..2822764 | - | 642 | WP_115167266.1 | leucine efflux protein LeuE | - |
| I6L80_RS12775 (I6L80_12775) | 2823250..2824104 | + | 855 | WP_115167267.1 | AraC family transcriptional regulator | - |
| I6L80_RS12780 (I6L80_12780) | 2824163..2824864 | + | 702 | WP_115167268.1 | AzlC family ABC transporter permease | - |
| I6L80_RS12785 (I6L80_12785) | 2824861..2825175 | + | 315 | WP_115167269.1 | AzlD domain-containing protein | - |
| I6L80_RS12790 (I6L80_12790) | 2825367..2825834 | + | 468 | WP_115167270.1 | DUF1456 family protein | - |
| I6L80_RS12795 (I6L80_12795) | 2825923..2826384 | + | 462 | WP_004910826.1 | DUF2384 domain-containing protein | Antitoxin |
| I6L80_RS12800 (I6L80_12800) | 2826381..2826839 | + | 459 | WP_217007720.1 | RES domain-containing protein | Toxin |
| I6L80_RS12805 (I6L80_12805) | 2826840..2827730 | - | 891 | WP_109912199.1 | LysR family transcriptional regulator | - |
| I6L80_RS12810 (I6L80_12810) | 2827776..2828735 | - | 960 | WP_115167271.1 | acetyl-CoA carboxylase carboxyl transferase subunit alpha | - |
| I6L80_RS12815 (I6L80_12815) | 2828841..2829263 | - | 423 | WP_115167272.1 | helix-turn-helix domain-containing protein | - |
| I6L80_RS12820 (I6L80_12820) | 2829294..2829821 | - | 528 | WP_232800742.1 | GNAT family N-acetyltransferase | - |
| I6L80_RS12825 (I6L80_12825) | 2829838..2831304 | - | 1467 | WP_042851594.1 | AMP nucleosidase | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 153 a.a. Molecular weight: 17204.77 Da Isoelectric Point: 6.2048
>T207042 WP_217007720.1 NZ_CP077317:2826381-2826839 [Providencia rettgeri]
MILYRLVKSSFIHDAWSGQGAMLYGGRWNHKGTPSVYTSTSISLATLEILVHINQDLLLNQFSLLSIDINDRYVMKLSLD
HLPTDWQQDPAPTSTMDIGTTWLNNQDSLVLLIPSCIIPYEYNAIINPLHPQFQKALHTVKPLDFSVDPRLA
MILYRLVKSSFIHDAWSGQGAMLYGGRWNHKGTPSVYTSTSISLATLEILVHINQDLLLNQFSLLSIDINDRYVMKLSLD
HLPTDWQQDPAPTSTMDIGTTWLNNQDSLVLLIPSCIIPYEYNAIINPLHPQFQKALHTVKPLDFSVDPRLA
Download Length: 459 bp
>T207042 NZ_CP102853:3480580-3481122 [Escherichia coli]
ATGGTCGACAAGCATGAAGAGATTACTCTGCCCATAGTCCTCTCCTGTAATTATCAGTCTGATATTACTTATCCTGGGCA
AAAACAGTTTGATTGCGGTAACCCTGTTATCGATAAATTTGTACGCGCATCGCTAAAGAAAAGTGTGCGTAATAGCGACT
GTGCGGCTAAAGCACTTATTGACAGACAAAGTGGTGAACTGATCGGCATCTGTACTTTTACGGCATATTCGCTGGAAAAA
CAACGCGTTTCTGGCGTCCTTCAGGGTTCACAACCTTCAGAAATTGGTGTTGTCAGATTAGTCATGTTGGGGGTAGCACG
GAAGTATCAAAAGCGGGGCTTTGGTCAGGACCTACTATGTGATTTTTTTGAACATGTAAAAATAATTCACCAGGCATTAC
CAATTAAAGGGGTTTATCTTGATGCTGACCCTGCCGCCATTAATTTTTATGCTCGTCTCGGCTTTGTTCAGCTTTCAGCG
ACACCAAATGCTTTTGGTGCTGTACCTATGTTTTTGGCGATTCAGCATATTCTCGCGGCTTAG
ATGGTCGACAAGCATGAAGAGATTACTCTGCCCATAGTCCTCTCCTGTAATTATCAGTCTGATATTACTTATCCTGGGCA
AAAACAGTTTGATTGCGGTAACCCTGTTATCGATAAATTTGTACGCGCATCGCTAAAGAAAAGTGTGCGTAATAGCGACT
GTGCGGCTAAAGCACTTATTGACAGACAAAGTGGTGAACTGATCGGCATCTGTACTTTTACGGCATATTCGCTGGAAAAA
CAACGCGTTTCTGGCGTCCTTCAGGGTTCACAACCTTCAGAAATTGGTGTTGTCAGATTAGTCATGTTGGGGGTAGCACG
GAAGTATCAAAAGCGGGGCTTTGGTCAGGACCTACTATGTGATTTTTTTGAACATGTAAAAATAATTCACCAGGCATTAC
CAATTAAAGGGGTTTATCTTGATGCTGACCCTGCCGCCATTAATTTTTATGCTCGTCTCGGCTTTGTTCAGCTTTCAGCG
ACACCAAATGCTTTTGGTGCTGTACCTATGTTTTTGGCGATTCAGCATATTCTCGCGGCTTAG
Antitoxin
Download Length: 154 a.a. Molecular weight: 17060.54 Da Isoelectric Point: 9.9140
>AT207042 WP_004910826.1 NZ_CP077317:2825923-2826384 [Providencia rettgeri]
MRNYIPTTPLQPTASSFKPLWRHVGLPAERGIELTHFLRQGLSVSVLDNIQEWSGMSKTELLRISGINERNIARRKNAGQ
PLNADESERIARLVRVFDAAVRLFNGDKHAAGDWLNHPVKGLGHLRPIELIATESGAIEVIDLIGRIEHGVFS
MRNYIPTTPLQPTASSFKPLWRHVGLPAERGIELTHFLRQGLSVSVLDNIQEWSGMSKTELLRISGINERNIARRKNAGQ
PLNADESERIARLVRVFDAAVRLFNGDKHAAGDWLNHPVKGLGHLRPIELIATESGAIEVIDLIGRIEHGVFS
Download Length: 462 bp
>AT207042 NZ_CP102853:3480285-3480596 [Escherichia coli]
ATGCCTGGAAAAACAGCCACTCTACCCGATGTCGATAAAACGCTGAAAAATGCGCGGGTCGAACTCAAAACCAGTCCCGA
CGCCAAAAACAAACTTCGTGAAGCTGCGCAAGCCGTTGGGGTAGATTTAAGCGCTTTTATTTTGAGCGCTGCTATGGAAC
GCGCCGAAAGTGTGCTTGATAACCAACGTCGCCGTGAGCTTTCGAATCAAAGCTGGGAACTGATGAACCAACTCATCGCT
GAACCTGCTCAACCGACGCTCGCCCTCAAGGCGTTAATGAAAAGGAAAAACAGCGATGGTCGACAAGCATGA
ATGCCTGGAAAAACAGCCACTCTACCCGATGTCGATAAAACGCTGAAAAATGCGCGGGTCGAACTCAAAACCAGTCCCGA
CGCCAAAAACAAACTTCGTGAAGCTGCGCAAGCCGTTGGGGTAGATTTAAGCGCTTTTATTTTGAGCGCTGCTATGGAAC
GCGCCGAAAGTGTGCTTGATAACCAACGTCGCCGTGAGCTTTCGAATCAAAGCTGGGAACTGATGAACCAACTCATCGCT
GAACCTGCTCAACCGACGCTCGCCCTCAAGGCGTTAATGAAAAGGAAAAACAGCGATGGTCGACAAGCATGA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|