Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/COG3657-dnstrm_HI1420
Location 86628..87157 Replicon plasmid pGMI1000MP
Accession NC_003296
Organism Ralstonia solanacearum GMI1000

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag RS_RS17560 Protein ID WP_011003396.1
Coordinates 86930..87157 (-) Length 76 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag RS_RS17555 Protein ID WP_016722339.1
Coordinates 86628..86933 (-) Length 102 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
RS_RS17540 82946..83227 - 282 WP_011003390.1 hypothetical protein -
RS_RS17545 83358..83642 - 285 WP_011003391.1 hypothetical protein -
RS_RS25855 83947..84164 + 218 Protein_71 hypothetical protein -
RS_RS25860 84322..84999 + 678 Protein_72 hypothetical protein -
RS_RS17550 85102..86415 - 1314 WP_011003394.1 metabolite/H+ symporter -
RS_RS17555 86628..86933 - 306 WP_016722339.1 putative addiction module antidote protein Antitoxin
RS_RS17560 86930..87157 - 228 WP_011003396.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
RS_RS17565 87313..88512 - 1200 WP_011003397.1 MFS transporter -
RS_RS17570 88639..89460 - 822 WP_011003398.1 GntR family transcriptional regulator -
RS_RS17575 89638..90189 - 552 WP_011003399.1 helix-turn-helix transcriptional regulator -
RS_RS17580 90322..90921 + 600 WP_011003400.1 GNAT family N-acetyltransferase -
RS_RS25865 91030..91389 + 360 Protein_80 recombinase family protein -
RS_RS25870 91662..91958 - 297 Protein_81 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - cyaB / flgC / flgG / fliM / fliG / fliI / acrB / adeG / cheY / cheB / cheW / motA 1..2094509 2094509


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(12-62)

Antitoxin

Cro/C1-type helix-turn-helix domain

(52-96)


Sequences

Toxin        


Download         Length: 76 a.a.        Molecular weight: 8544.80 Da        Isoelectric Point: 6.4584

>T20704 WP_011003396.1 NC_003296:c87157-86930 [Ralstonia solanacearum GMI1000]
VRIDRLQMGNPGDMKAVRDGIRELRIDHGPGDRLYFVRHGVVLIVLLCGGDKSTQETDIRRAIDLSRRLDVDDME

Download         Length: 228 bp

>T20704 NC_003296:c87157-86930 [Ralstonia solanacearum GMI1000]
GTGCGCATCGACCGCCTGCAGATGGGCAACCCGGGCGACATGAAAGCGGTCCGTGACGGCATCCGTGAGCTGCGGATCGA
TCATGGGCCGGGCGACCGCTTGTACTTCGTGCGGCATGGCGTGGTCCTGATCGTACTGCTCTGCGGCGGCGACAAGTCGA
CGCAGGAAACCGATATCCGTCGCGCAATTGACCTGTCCCGCCGTCTCGACGTGGACGACATGGAATGA

Antitoxin


Download         Length: 102 a.a.        Molecular weight: 10967.57 Da        Isoelectric Point: 7.2780

>AT20704 WP_016722339.1 NC_003296:c86933-86628 [Ralstonia solanacearum GMI1000]
MTMAQRTIKTRPWDSAEHLRTEADIAAYLDACLEEAGDDPAFITHALGVVARSRGMTQLARETGMTREGLYKALSEGGNP
SFATVLKVIRALGIRLHAVPT

Download         Length: 306 bp

>AT20704 NC_003296:c86933-86628 [Ralstonia solanacearum GMI1000]
ATGACGATGGCCCAACGCACCATCAAGACCCGGCCGTGGGATTCGGCCGAACACCTCCGGACCGAAGCGGACATCGCCGC
CTACCTCGACGCCTGCCTGGAAGAAGCCGGAGATGACCCCGCCTTCATCACGCATGCGCTGGGCGTGGTCGCGCGCTCGC
GCGGCATGACGCAGCTCGCCCGCGAGACCGGGATGACCCGCGAAGGGCTGTACAAGGCGCTTTCCGAGGGCGGCAATCCG
AGCTTTGCGACCGTGCTGAAGGTCATCCGGGCGCTCGGCATCCGGCTGCACGCCGTGCCGACCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References