Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type IV Classification (family/domain) yeeUV (cbtA-cbeA)/CbtA-CbeA
Location 1356689..1357472 Replicon chromosome
Accession NZ_CP077300
Organism Citrobacter braakii strain FDAARGOS 1422

Toxin (Protein)


Gene name yeeV Uniprot ID -
Locus tag I6L52_RS06415 Protein ID WP_151223123.1
Coordinates 1356689..1357063 (-) Length 125 a.a.

Antitoxin (Protein)


Gene name yeeU Uniprot ID -
Locus tag I6L52_RS06420 Protein ID WP_217124873.1
Coordinates 1357113..1357472 (-) Length 120 a.a.

Genomic Context


I6L52_RS06390I6L52_RS06400I6L52_RS06405I6L52_RS06410I6L52_RS06395I6L52_RS06415I6L52_RS06420I6L52_RS06425I6L52_RS06430I6L52_RS06435I6L52_RS06440I6L52_RS06445I6L52_RS06450I6L52_RS06455I6L52_RS06460
Location: 1352018..1352515 (498 bp)
Type: Others
Protein ID: WP_151222420.1
Location: 1353445..1354473 (1029 bp)
Type: Others
Protein ID: WP_151222422.1
Location: 1355161..1356150 (990 bp)
Type: Others
Protein ID: WP_217124872.1
Location: 1356154..1356612 (459 bp)
Type: Others
Protein ID: WP_223949818.1
Location: 1352529..1353071 (543 bp)
Type: Others
Protein ID: WP_151222421.1
Location: 1356689..1357063 (375 bp)
Type: Toxin
Protein ID: WP_151223123.1
Location: 1357113..1357472 (360 bp)
Type: Antitoxin
Protein ID: WP_217124873.1
Location: 1357495..1357716 (222 bp)
Type: Others
Protein ID: WP_004114632.1
Location: 1357730..1358212 (483 bp)
Type: Others
Protein ID: WP_151222425.1
Location: 1358209..1358442 (234 bp)
Type: Others
Protein ID: WP_151222426.1
Location: 1358453..1358932 (480 bp)
Type: Others
Protein ID: WP_151222427.1
Location: 1359012..1359833 (822 bp)
Type: Others
Protein ID: WP_151222428.1
Location: 1359944..1360156 (213 bp)
Type: Others
Protein ID: WP_010434180.1
Location: 1360237..1360596 (360 bp)
Type: Others
Protein ID: WP_010434179.1
Location: 1360651..1361115 (465 bp)
Type: Others
Protein ID: WP_151222429.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
I6L52_RS06390 (1352018)1352018..1352515+498WP_151222420.1Mov34/MPN/PAD-1 family protein-
I6L52_RS06395 (1352529)1352529..1353071-543WP_151222421.13'-5' exonuclease-
I6L52_RS06400 (1353445)1353445..1354473+1029WP_151222422.1SMEK domain-containing protein-
I6L52_RS06405 (1355161)1355161..1356150+990WP_217124872.1glycosyltransferase-
I6L52_RS06410 (1356154)1356154..1356612+459WP_223949818.1hypothetical protein-
I6L52_RS06415 (1356689)1356689..1357063-375WP_151223123.1TA system toxin CbtA family proteinToxin
I6L52_RS06420 (1357113)1357113..1357472-360WP_217124873.1type IV toxin-antitoxin system YeeU family antitoxinAntitoxin
I6L52_RS06425 (1357495)1357495..1357716-222WP_004114632.1DUF987 domain-containing protein-
I6L52_RS06430 (1357730)1357730..1358212-483WP_151222425.1DNA repair protein RadC-
I6L52_RS06435 (1358209)1358209..1358442-234WP_151222426.1hypothetical protein-
I6L52_RS06440 (1358453)1358453..1358932-480WP_151222427.1antirestriction protein-
I6L52_RS06445 (1359012)1359012..1359833-822WP_151222428.1DUF932 domain-containing protein-
I6L52_RS06450 (1359944)1359944..1360156-213WP_010434180.1hypothetical protein-
I6L52_RS06455 (1360237)1360237..1360596-360WP_010434179.1hypothetical protein-
I6L52_RS06460 (1360651)1360651..1361115-465WP_151222429.1hypothetical protein-

Associated MGEs


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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(1-112)

Antitoxin

(15-114)


Sequences


Toxin        


Download         Length: 125 a.a.        Molecular weight: 13885.96 Da        Isoelectric Point: 9.7700

>T206997 WP_151223123.1 NZ_CP077300:c1357063-1356689 [Citrobacter braakii]
MQTQSRPPQRAASSLLSLVEIWQKLLEYLLKQHYGLMLNDTPFGNDEVIQKHIDAGISLCDAVNFIVEKYDLVRTDRHGF
SVKEQSPFIGSIDMLRARKATGLMTRKGYKTVTDITGGRSSGGK

Download         Length: 375 bp

>T206997 NZ_CP102837:15767-16078 [Klebsiella pneumoniae]
ATGCACGTAATTTCAAAAGAGCCTTTTGAGGAAGCGGCAAAGCGATATCCCAACGATTCGTTAGCCATTCGGGCGTTGTA
CCGCTTAGTGCGCGAGACGGACTTCTCTTCTCCAGCTGAGATGCTAACTCTGATACCGAGCCTGGATAATTTTAAGTACA
GGAATAAGTGGTGGGTTTTGGATGTAGGGGGCAACAACTTAAGGGTTATCGCCTATATCAATTTCGTAAATAAGCGCTTC
TACGTGAAGCACATCGCAACCCACGCTGATTACGACAAGTTGACCCGCTATTACAGGGAGAACAAAGAATGA

Antitoxin


Download         Length: 120 a.a.        Molecular weight: 13338.41 Da        Isoelectric Point: 7.3727

>AT206997 WP_217124873.1 NZ_CP077300:c1357472-1357113 [Citrobacter braakii]
MQKATRVINHNIAEPWWGLRRNITPCFGARLVQEGNHLHYLADRASIAGTFSDADLRHLDQAFPVLMKQMELMLTSNELT
PHIQRCITLHAKGLICEADTLGSCGYLYIVIYPTSATTA

Download         Length: 360 bp

>AT206997 NZ_CP102837:16075-16494 [Klebsiella pneumoniae]
ATGATTACCGACACTGCAAAAGCCATTGAAGCAACCAAACAACTCGTAGCTGCCGTCCCCTTCCTAGGGGGCAGTTCTTC
CGAGAGCGATTACCGCGAAGCGATGGAGCTGGTGGATTATCTGATCGAGAACGACGACGAGAACCCACTTATTGACTTCC
TGGCGAGTAAGATTGCCGACTATGAAGATAACAGCCCTCGTTTCGCTGAGTTCAACAAAGCTATTGCTGAAATACCAGTC
GGCGTTGCACTTCTGCGAACCCTGATTGACCAGCACAAGCTGTCTTATTCAGACCTTAAGGATGAGATCGGATCTAAATC
ATTGGTCAGCCAAATCCTGTCAGGGCAGCGCTCTTTGACCATCACTCACATAAAAGCTCTTTCCGCGCGCTTCGGTGTAA
AACCTGAGTGGTTCCTATAA

Similar Proteins


Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures


Toxin

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Source
ID
Structure
No matching records found


Antitoxin

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Source
ID
Structure
No matching records found

References