Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 3188444..3188590 Replicon chromosome
Accession NZ_CP077293
Organism Klebsiella aerogenes strain FDAARGOS 1442

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 3188452..3188555 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 3188444..3188590 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
I6L72_RS14950 (I6L72_14950) 3183746..3184264 + 519 WP_015366014.1 spore coat U domain-containing protein -
I6L72_RS14955 (I6L72_14955) 3184282..3185031 + 750 WP_015366013.1 molecular chaperone -
I6L72_RS14960 (I6L72_14960) 3185034..3187358 + 2325 WP_015705944.1 fimbria/pilus outer membrane usher protein -
I6L72_RS14965 (I6L72_14965) 3187371..3188324 + 954 WP_015705945.1 spore coat U domain-containing protein -
- 3188444..3188590 + 147 - - Antitoxin
- 3188452..3188555 - 104 - - Toxin
I6L72_RS14970 (I6L72_14970) 3188712..3189053 - 342 WP_015705946.1 YebY family protein -
I6L72_RS14975 (I6L72_14975) 3189067..3189936 - 870 WP_015705947.1 copper homeostasis membrane protein CopD -
I6L72_RS14980 (I6L72_14980) 3189940..3190314 - 375 WP_026612268.1 CopC domain-containing protein YobA -
I6L72_RS14985 (I6L72_14985) 3190449..3190679 + 231 WP_015366007.1 DNA polymerase III subunit theta -
I6L72_RS14990 (I6L72_14990) 3190759..3191418 + 660 WP_217068080.1 exodeoxyribonuclease X -
I6L72_RS14995 (I6L72_14995) 3191421..3193481 - 2061 WP_015705949.1 oligopeptidase B -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T206985 NZ_CP077293:c3188555-3188452 [Klebsiella aerogenes]
GGCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 147 bp

>AT206985 NZ_CP077293:3188444-3188590 [Klebsiella aerogenes]
TAATAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAA
GTTGGCATTAATGCAGGCTAAGTCGCCTTGCCTTATAAGAATAGTTGACTGTGACAGGTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References