Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1937442..1937646 Replicon chromosome
Accession NZ_CP077291
Organism Citrobacter farmeri strain FDAARGOS 1423

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1937537..1937640 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1937442..1937646 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
I6L53_RS09100 (I6L53_09100) 1933959..1934621 - 663 WP_042318450.1 exodeoxyribonuclease X -
I6L53_RS09105 (I6L53_09105) 1934645..1935301 - 657 WP_042318452.1 carbon-nitrogen hydrolase family protein -
I6L53_RS09110 (I6L53_09110) 1935409..1935639 - 231 WP_042318454.1 DNA polymerase III subunit theta -
I6L53_RS09115 (I6L53_09115) 1935777..1936151 + 375 WP_042318457.1 CopC domain-containing protein YobA -
I6L53_RS09120 (I6L53_09120) 1936154..1937026 + 873 WP_042318459.1 copper homeostasis membrane protein CopD -
I6L53_RS09125 (I6L53_09125) 1937043..1937381 + 339 WP_042318461.1 YebY family protein -
- 1937442..1937646 - 205 - - Antitoxin
- 1937537..1937640 + 104 - - Toxin
I6L53_RS09130 (I6L53_09130) 1937790..1938452 + 663 WP_042318462.1 protein-serine/threonine phosphatase -
I6L53_RS09135 (I6L53_09135) 1938453..1938644 - 192 WP_042318465.1 YebW family protein -
I6L53_RS09140 (I6L53_09140) 1938746..1938982 - 237 WP_167382411.1 YebV family protein -
I6L53_RS09145 (I6L53_09145) 1939097..1940536 - 1440 WP_072015681.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T206963 NZ_CP077291:1937537-1937640 [Citrobacter farmeri]
GGCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 205 bp

>AT206963 NZ_CP077291:c1937646-1937442 [Citrobacter farmeri]
ACAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGT
TGGCATTAATGCAGGCTAAGTCGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTCCGCGGCTTACGCGG
CCTGAAAAAAACGGTGATGGTCACTGCCTGAAATGTAAAAACCGC

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References