Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) yeeUV (cbtA-cbeA)/CbtA-CbeA
Location 2090458..2091138 Replicon chromosome
Accession NZ_CP077290
Organism Enterobacter cancerogenus strain FDAARGOS 1428

Toxin (Protein)


Gene name yeeV Uniprot ID -
Locus tag I6L58_RS09795 Protein ID WP_176399440.1
Coordinates 2090458..2090772 (-) Length 105 a.a.

Antitoxin (Protein)


Gene name yeeU Uniprot ID -
Locus tag I6L58_RS09800 Protein ID WP_088208765.1
Coordinates 2090815..2091138 (-) Length 108 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
I6L58_RS09780 (I6L58_09780) 2088098..2089048 - 951 WP_088208769.1 nucleotidyl transferase AbiEii/AbiGii toxin family protein -
I6L58_RS09785 (I6L58_09785) 2089041..2089436 - 396 WP_088208768.1 DUF6088 family protein -
I6L58_RS09790 (I6L58_09790) 2089511..2090344 - 834 WP_088208767.1 DUF4942 domain-containing protein -
I6L58_RS09795 (I6L58_09795) 2090458..2090772 - 315 WP_176399440.1 TA system toxin CbtA family protein Toxin
I6L58_RS09800 (I6L58_09800) 2090815..2091138 - 324 WP_088208765.1 type IV toxin-antitoxin system YeeU family antitoxin Antitoxin
I6L58_RS09805 (I6L58_09805) 2091151..2091621 - 471 WP_088208764.1 DNA repair protein RadC -
I6L58_RS09810 (I6L58_09810) 2091692..2092513 - 822 WP_088208763.1 DUF932 domain-containing protein -
I6L58_RS09815 (I6L58_09815) 2092623..2093033 - 411 WP_230586359.1 IrmA family protein -
I6L58_RS09820 (I6L58_09820) 2093216..2093863 - 648 WP_043018271.1 hypothetical protein -
I6L58_RS09825 (I6L58_09825) 2093869..2094570 - 702 WP_088208762.1 WYL domain-containing protein -
I6L58_RS09830 (I6L58_09830) 2094783..2095658 - 876 WP_088208761.1 GTPase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 2066839..2111832 44993


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

CbtA toxin of type IV toxin-antitoxin system

(9-103)

Antitoxin

Antitoxin CbeA

(7-106)


Sequences

Toxin        


Download         Length: 105 a.a.        Molecular weight: 11756.26 Da        Isoelectric Point: 5.0221

>T206946 WP_176399440.1 NZ_CP077290:c2090772-2090458 [Enterobacter cancerogenus]
ISTVPAKVPVSSRPSPVQVWQQLLTYLLDHHYGLTLNDTPFHDDAAIEEHIDAGITLADAVNFLVERYELVRIDRQGFSW
QEQTPFLTATDILRARRATGLINT

Download         Length: 315 bp

>T206946 NZ_CP102816:3861-4148 [Acinetobacter baumannii]
ATGGAACAGTATTTTGAATGGGATGAGGCTAAGAATCGAAAGAATCAGAAAAAGCATGATATCTCTTTCGAAACTGCAAG
CCTTGTTTTTGAAGATCCATTACGGATCTCAATCCAAGACAGACATACCAATGGTGAAGAACGTTGGCAAACCATTGGAC
GAGTTAAAGGCGTACTAATGTTATTGGTGGCTCACACCATTTTTGATGAAGATGACTGTGAAATCATCCGAATCATTAGT
GCAAGGCAAGTCACTAAAGCGGAGCGAAACAAATATGAGCATGGTTAG

Antitoxin


Download         Length: 108 a.a.        Molecular weight: 12046.84 Da        Isoelectric Point: 6.7057

>AT206946 WP_088208765.1 NZ_CP077290:c2091138-2090815 [Enterobacter cancerogenus]
MSITPPHEWGLQSDITPRFGARLVQEGNRLYYLADRAGLTGSFSPMHLQKLDLAFPLFVEQLEDMLRAGELNPHQQRQVK
IQLASLTCIADPRGSCGYVYISIYPTP

Download         Length: 324 bp

>AT206946 NZ_CP102816:4135-4449 [Acinetobacter baumannii]
ATGAGCATGGTTAGATACTCACACAAAGAGCTGAATGAGAAATTTGGTGAGAAGCAAGATGCTGAAATTCAACGCTTGCT
TGCTAAAGGCACGGTTCCTGATGATCAGCTAGATCTATCAGATATTCCTGAAATTACAGACTGGAGCAATGCTGTACGCC
AAAATCAATTTTACCGCCCAGTAAAGCAACAAACTTCAATTCGGTTAGATGCTGATGTACTTGCTTGGTTCAAAGCACAA
GGCAAAGGTTATCAAACACGTATGAATGAAATTTTACGAGATGCTATGCTAAAAGAATTAAAAAATCATCAATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References