206891

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 4781751..4782286 Replicon chromosome
Accession NZ_CP077262
Organism Citrobacter pasteurii strain FDAARGOS 1424

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag I6L54_RS23070 Protein ID WP_005132544.1
Coordinates 4781999..4782286 (+) Length 96 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag I6L54_RS23065 Protein ID WP_005132543.1
Coordinates 4781751..4782002 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
I6L54_RS23035 (I6L54_23040) 4777246..4778004 + 759 WP_005132536.1 phosphonate C-P lyase system protein PhnK -
I6L54_RS23040 (I6L54_23045) 4778113..4778793 + 681 WP_005132537.1 phosphonate C-P lyase system protein PhnL -
I6L54_RS23045 (I6L54_23050) 4778790..4779926 + 1137 WP_005132539.1 alpha-D-ribose 1-methylphosphonate 5-triphosphate diphosphatase -
I6L54_RS23050 (I6L54_23055) 4779929..4780483 + 555 WP_005132540.1 ribose 1,5-bisphosphokinase -
I6L54_RS23055 (I6L54_23060) 4780470..4780904 + 435 WP_005132541.1 aminoalkylphosphonate N-acetyltransferase -
I6L54_RS23060 (I6L54_23065) 4780914..4781672 + 759 WP_005132542.1 phosphonate metabolism protein PhnP -
I6L54_RS23065 (I6L54_23070) 4781751..4782002 + 252 WP_005132543.1 plasmid stabilization protein Antitoxin
I6L54_RS23070 (I6L54_23075) 4781999..4782286 + 288 WP_005132544.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
I6L54_RS23075 (I6L54_23080) 4782283..4782612 - 330 WP_040234033.1 DDRRRQL repeat protein YjdP -
I6L54_RS23080 (I6L54_23085) 4782682..4784946 - 2265 WP_005132546.1 hybrid sensor histidine kinase/response regulator -
I6L54_RS23085 (I6L54_23090) 4785061..4786584 + 1524 WP_005132547.1 sugar ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-83)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 96 a.a.        Molecular weight: 11061.98 Da        Isoelectric Point: 10.2540

>T206891 WP_005132544.1 NZ_CP077262:4781999-4782286 [Citrobacter pasteurii]
MSYTVKFREDALKEWQKLDTAIQQQFAKKLKKCCENPHVPSAKLRGIKDCYKIKLRTSGFRLVYQVIDDTLVIAVVAVGK
RERSEVYNLASERLR

Download         Length: 288 bp

>T206891 NZ_CP102748:c943208-942951 [Streptococcus suis]
ATGAAGACCTGTTATAAACTCGTACCGACCAGTCGTTTTATTAAACAGTTGAAAAAGTTGGACAAATTTACCCAAAAACA
GATTACCAACTACTTGTCCAGTCATGTGACTGACAACCCTAGACAATACGGAAAAGCCTTGACTGCTAATCGTTCTGGCC
AATGGCGCTATCGTATCGGCAATTACAGGGTTATCGTTAATATTGAAGATGATAAATTGATTGTGACAAGCATAAAAATG
AGAAATGGAAGTATATAA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9198.55 Da        Isoelectric Point: 4.4262

>AT206891 WP_005132543.1 NZ_CP077262:4781751-4782002 [Citrobacter pasteurii]
MPHIILSDTTASVSELKKNPMATVSAGNGFPVAILNRNQPAFYCVPAELYEKMLDALDDQQLVKLVHERSQQPLVDVDLD
SFL

Download         Length: 252 bp

>AT206891 NZ_CP102748:c943443-943192 [Streptococcus suis]
ATGGCAGCTATTACATTGAAAGTTTCTGAGCAGGACAAGCTCTTTATGCAGGCTATGGCAAAGTTTGAAGGTGTCAGTTT
GTCAGAACTCATTCGGACTAAAACCCTTGAAGCTCTCGAAGATGAATATGATGCCCGTGTGGCAGATATCGCTCTGTCTG
AATACGAGGCAGACTTGGCGAAAGGCATTGAGCCGATTAGCTGGGAGGAAATGTTGGAAGAGTTGGGGTTGACGGATGAA
GACCTGTTATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References