Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | mosAT/AbiEii-AbiEi |
| Location | 1043133..1044831 | Replicon | chromosome |
| Accession | NZ_CP077262 | ||
| Organism | Citrobacter pasteurii strain FDAARGOS 1424 | ||
Toxin (Protein)
| Gene name | mosT | Uniprot ID | - |
| Locus tag | I6L54_RS05080 | Protein ID | WP_040229939.1 |
| Coordinates | 1043133..1044062 (-) | Length | 310 a.a. |
Antitoxin (Protein)
| Gene name | mosA | Uniprot ID | - |
| Locus tag | I6L54_RS05085 | Protein ID | WP_040229937.1 |
| Coordinates | 1044049..1044831 (-) | Length | 261 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| I6L54_RS05060 (I6L54_05060) | 1039263..1040351 | + | 1089 | WP_040229944.1 | type VI secretion system baseplate subunit TssG | - |
| I6L54_RS05065 (I6L54_05065) | 1040326..1040862 | + | 537 | WP_040229943.1 | type VI secretion system lipoprotein TssJ | - |
| I6L54_RS05070 (I6L54_05070) | 1040859..1041302 | + | 444 | WP_040229942.1 | type VI secretion system baseplate subunit TssE | - |
| I6L54_RS05075 (I6L54_05075) | 1041304..1042644 | + | 1341 | WP_040229940.1 | ImpA domain-containing protein | - |
| I6L54_RS05080 (I6L54_05080) | 1043133..1044062 | - | 930 | WP_040229939.1 | nucleotidyl transferase AbiEii/AbiGii toxin family protein | Toxin |
| I6L54_RS05085 (I6L54_05085) | 1044049..1044831 | - | 783 | WP_040229937.1 | type IV toxin-antitoxin system AbiEi family antitoxin domain-containing protein | Antitoxin |
| I6L54_RS05090 (I6L54_05090) | 1045062..1046267 | + | 1206 | WP_040229934.1 | hypothetical protein | - |
| I6L54_RS05095 (I6L54_05095) | 1046264..1046773 | + | 510 | WP_040229932.1 | hypothetical protein | - |
| I6L54_RS05100 (I6L54_05100) | 1046770..1048746 | + | 1977 | WP_040229931.1 | AAA family ATPase | - |
| I6L54_RS05110 (I6L54_05110) | 1049141..1049602 | + | 462 | WP_040229929.1 | hypothetical protein | - |
| I6L54_RS05115 (I6L54_05115) | 1049605..1049826 | + | 222 | WP_040229952.1 | helix-turn-helix transcriptional regulator | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Genomic island | - | - | 1014080..1061259 | 47179 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 310 a.a. Molecular weight: 34932.23 Da Isoelectric Point: 6.0437
>T206878 WP_040229939.1 NZ_CP077262:c1044062-1043133 [Citrobacter pasteurii]
MDLRDSYARQVRLLMTALPHVAKESCFALKGGTAINLFVQDFPRLSVDIDLAYKTYVDRDTDLAAINDALMRITESLNGR
LGITAIRQENKADEKRIIVNTADAQIKIEVSPVWRGLLLPSTEMPVCEQVEMEYGFTTMNVVSLADLYGGKICAALDRQH
PRDLFDVLNMLDKPGLTREIFDGFLCYLAGHPRPIAELLAPNWDTAQIATLYAQEFSGMTQRETSLESLLSVTTLLPQAL
KSHLTERDRQFLLSYKQNNPDWSLYRYPEIQHLPAIRWKLRNLAVLNDKNPAKYAAAVSKLEGVLAQYI
MDLRDSYARQVRLLMTALPHVAKESCFALKGGTAINLFVQDFPRLSVDIDLAYKTYVDRDTDLAAINDALMRITESLNGR
LGITAIRQENKADEKRIIVNTADAQIKIEVSPVWRGLLLPSTEMPVCEQVEMEYGFTTMNVVSLADLYGGKICAALDRQH
PRDLFDVLNMLDKPGLTREIFDGFLCYLAGHPRPIAELLAPNWDTAQIATLYAQEFSGMTQRETSLESLLSVTTLLPQAL
KSHLTERDRQFLLSYKQNNPDWSLYRYPEIQHLPAIRWKLRNLAVLNDKNPAKYAAAVSKLEGVLAQYI
Download Length: 930 bp
>T206878 NZ_CP102745:c511608-511351 [Ornithobacterium rhinotracheale]
ATTAAATATATTTTTGTAGATGAATCTTGGGAAGATTATCTATATTGGCAAAAAAACGATAAACGAAAGCTTAAAAGAAT
CAATGCTTTGTTGAAAGATATTTCGCGCACGCCTTTTGAAGGTATTGGCAAACCTGAGCCATTAAAACATAAATATTCAG
GATTTTGGTCACGCAGAATTGATGATGAACATTGTTTAATTTACCGTTACGAAGAAGATAAAATCCTGATTGCCAAATGT
AGATTTCATTATGATTAA
ATTAAATATATTTTTGTAGATGAATCTTGGGAAGATTATCTATATTGGCAAAAAAACGATAAACGAAAGCTTAAAAGAAT
CAATGCTTTGTTGAAAGATATTTCGCGCACGCCTTTTGAAGGTATTGGCAAACCTGAGCCATTAAAACATAAATATTCAG
GATTTTGGTCACGCAGAATTGATGATGAACATTGTTTAATTTACCGTTACGAAGAAGATAAAATCCTGATTGCCAAATGT
AGATTTCATTATGATTAA
Antitoxin
Download Length: 261 a.a. Molecular weight: 29463.87 Da Isoelectric Point: 9.1806
>AT206878 WP_040229937.1 NZ_CP077262:c1044831-1044049 [Citrobacter pasteurii]
MPNYINWLMQNTQPGQVLLQSWLTRNGIDRKLSYLYVQNGWIRRIAHGVYCRMGREPDWVDAVYCLQTQWEKPVRVAGLT
SLALQGHAHYTEPGRQQIWLALPAYVKLPGWFAAFEQSAKFVTLYTSGLTVDVTPFTTKLNIGDRQLTGSIPELAAYEIA
CGVPSLISFEHADALFQGMNLLSPRKLQTLLCASHSVKTNRVMLYLARRNAHPYFQYLYQRGIETGTGKRQIIPGGWLEP
DYQITVPRAFKPEGVEDGSA
MPNYINWLMQNTQPGQVLLQSWLTRNGIDRKLSYLYVQNGWIRRIAHGVYCRMGREPDWVDAVYCLQTQWEKPVRVAGLT
SLALQGHAHYTEPGRQQIWLALPAYVKLPGWFAAFEQSAKFVTLYTSGLTVDVTPFTTKLNIGDRQLTGSIPELAAYEIA
CGVPSLISFEHADALFQGMNLLSPRKLQTLLCASHSVKTNRVMLYLARRNAHPYFQYLYQRGIETGTGKRQIIPGGWLEP
DYQITVPRAFKPEGVEDGSA
Download Length: 783 bp
>AT206878 NZ_CP102745:c511865-511611 [Ornithobacterium rhinotracheale]
ATGCTAGTTACCAATATTTCAGAATTTAGAAAAGATTTAAAATCCTATTTAAACAAGGTTGCAAAAAACTTTGAAACCTT
AATCATTAATCGTGGAAAAGAATCTGCAATCGTGGTTTTGTCGCTTGATGAGTATAATTCTTTGATGGCGACAAATTATG
AACTGTCTTCTCGCAAAAACGAACAGCATCTAGATGCTGCAATAGCAAAATTGAAATCAGGAGAATCATTTGAGAAAACA
CTGATTGAAGATTAA
ATGCTAGTTACCAATATTTCAGAATTTAGAAAAGATTTAAAATCCTATTTAAACAAGGTTGCAAAAAACTTTGAAACCTT
AATCATTAATCGTGGAAAAGAATCTGCAATCGTGGTTTTGTCGCTTGATGAGTATAATTCTTTGATGGCGACAAATTATG
AACTGTCTTCTCGCAAAAACGAACAGCATCTAGATGCTGCAATAGCAAAATTGAAATCAGGAGAATCATTTGAGAAAACA
CTGATTGAAGATTAA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
Structures
Toxin
| Source | ID | Structure |
|---|
Antitoxin
| Source | ID | Structure |
|---|