Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 1641605..1642262 Replicon chromosome
Accession NZ_CP077260
Organism Providencia rettgeri strain FDAARGOS 1449

Toxin (Protein)


Gene name cptA Uniprot ID A0A264VM08
Locus tag I6L79_RS07250 Protein ID WP_036958456.1
Coordinates 1641852..1642262 (+) Length 137 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID D4C097
Locus tag I6L79_RS07245 Protein ID WP_004261864.1
Coordinates 1641605..1641871 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
I6L79_RS07230 (I6L79_07230) 1638601..1639497 - 897 WP_036958457.1 hypothetical protein -
I6L79_RS07235 (I6L79_07235) 1639742..1640362 - 621 WP_004261871.1 HD domain-containing protein -
I6L79_RS07240 (I6L79_07240) 1640374..1641357 - 984 WP_004261867.1 tRNA-modifying protein YgfZ -
I6L79_RS07245 (I6L79_07245) 1641605..1641871 + 267 WP_004261864.1 FAD assembly factor SdhE Antitoxin
I6L79_RS07250 (I6L79_07250) 1641852..1642262 + 411 WP_036958456.1 protein YgfX Toxin
I6L79_RS07255 (I6L79_07255) 1642362..1642880 - 519 WP_004261816.1 flavodoxin FldB -
I6L79_RS07260 (I6L79_07260) 1642998..1643900 + 903 WP_004261814.1 site-specific tyrosine recombinase XerD -
I6L79_RS07265 (I6L79_07265) 1643922..1644626 + 705 WP_036958522.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
I6L79_RS07270 (I6L79_07270) 1644636..1646369 + 1734 WP_004261807.1 single-stranded-DNA-specific exonuclease RecJ -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(3-133)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 137 a.a.        Molecular weight: 15568.53 Da        Isoelectric Point: 10.7733

>T206871 WP_036958456.1 NZ_CP077260:1641852-1642262 [Providencia rettgeri]
VVLWKSNLSISWKTQLFSTCVHGVIGMFLLLAPWSPGNSMIWLPLLVVVVASWAKSQKNISKIKGVAVLVNGNKVQWKKN
EWRILKAPWLTRYGILLTLEALQGKPQKLHLWVAKDALSEENWRNLNQLLLQYPDI

Download         Length: 411 bp

>T206871 NZ_CP102739:c2848400-2848297 [Salmonella enterica subsp. enterica serovar Kentucky]
GGCAAGGCGATTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10684.24 Da        Isoelectric Point: 4.8942

>AT206871 WP_004261864.1 NZ_CP077260:1641605-1641871 [Providencia rettgeri]
MDIENKARIHWACRRGMRELDISIMPFFEYEYDDLTTHDKQVFVRLLECADPDLFNWLMNHGRPDDDELFRMIKLIQEKN
KNRGPVEI

Download         Length: 267 bp

>AT206871 NZ_CP102739:2848295-2848438 [Salmonella enterica subsp. enterica serovar Kentucky]
ATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGC
ATTAATGCAGGCTAAATCGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A264VM08

Antitoxin

Source ID Structure
AlphaFold DB A0A345M2Q5

References