Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 4237908..4238176 Replicon chromosome
Accession NZ_CP077242
Organism Escherichia fergusonii strain FDAARGOS 1438

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 4237946..4238049 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 4237908..4238176 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
I6L68_RS20285 4235065..4236504 + 1440 WP_002431585.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
I6L68_RS20290 4236623..4236859 + 237 WP_002431586.1 YebV family protein -
I6L68_RS20295 4236964..4237155 + 192 WP_002431587.1 YebW family protein -
I6L68_RS20300 4237156..4237812 - 657 WP_000812708.1 protein-serine/threonine phosphatase -
- 4237908..4238176 + 269 - - Antitoxin
- 4237946..4238049 - 104 - - Toxin
I6L68_RS20305 4238206..4238547 - 342 WP_000976177.1 YebY family protein -
I6L68_RS20310 4238559..4239431 - 873 WP_000928495.1 copper homeostasis membrane protein CopD -
I6L68_RS20315 4239434..4239808 - 375 WP_217059691.1 CopC domain-containing protein YobA -
I6L68_RS20320 4239947..4240177 + 231 WP_000700614.1 DNA polymerase III subunit theta -
I6L68_RS20325 4240284..4240940 + 657 WP_000075607.1 carbon-nitrogen hydrolase family protein -
I6L68_RS20330 4240964..4241626 + 663 WP_000946659.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T206856 NZ_CP077242:c4238049-4237946 [Escherichia fergusonii]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 269 bp

>AT206856 NZ_CP077242:4237908-4238176 [Escherichia fergusonii]
AAAGTCAGCGAATGGAATATTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References