Detailed information of TA system TA206779

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): /RES-TIGR02293
• Location: 1547145..1548058
• Replicon: chromosome
• Accession: NZ_CP077206
• Organism: Enterobacter bugandensis strain FDAARGOS 1427

Toxin (Protein)

• Gene name: -
• Uniprot ID: -
• Locus tag: I6L57_RS07330
• Protein ID: WP_088204937.1
• Coordinates: 1547145..1547618 (-)
• Length: 158 a.a.

Antitoxin (Protein)

• Gene name: -
• Uniprot ID: -
• Locus tag: I6L57_RS07335
• Protein ID: WP_045261776.1
• Coordinates: 1547615..1548058 (-)
• Length: 148 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
I6L57_RS07310 (I6L57_07310)	1543304..1544614	+	1311	WP_088204934.1	type I-F CRISPR-associated protein Csy1	-
I6L57_RS07315 (I6L57_07315)	1544611..1545546	+	936	WP_088204935.1	type I-F CRISPR-associated protein Csy2	-
I6L57_RS07320 (I6L57_07320)	1545560..1546558	+	999	WP_045261779.1	type I-F CRISPR-associated protein Csy3	-
I6L57_RS07325 (I6L57_07325)	1546568..1547122	+	555	WP_088204936.1	type I-F CRISPR-associated endoribonuclease Cas6/Csy4	-
I6L57_RS07330 (I6L57_07330)	1547145..1547618	-	474	WP_088204937.1	RES domain-containing protein	Toxin
I6L57_RS07335 (I6L57_07335)	1547615..1548058	-	444	WP_045261776.1	DUF2384 domain-containing protein	Antitoxin
I6L57_RS07340 (I6L57_07340)	1548676..1548894	-	219	WP_002211347.1	translation initiation factor IF-1	-
I6L57_RS07345 (I6L57_07345)	1549179..1549883	-	705	WP_041910636.1	leucyl/phenylalanyl-tRNA--protein transferase	-
I6L57_RS07350 (I6L57_07350)	1549929..1551650	-	1722	WP_088204938.1	cysteine/glutathione ABC transporter ATP-binding protein/permease CydC	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• RES domain (3-147)

Antitoxin

• Antitoxin Xre-like, helix-turn-helix domain (30-90)

Sequences

Toxin

Protein

• Length: 158 a.a.
• Molecular weight: 17531.88 Da
• Isoelectric Point: 5.0700

>T206779 WP_088204937.1 NZ_CP077206:c1547618-1547145 [Enterobacter bugandensis]
MIFYRLVTGRYASEAWSGSGANQYGGRWNHKGHPAVYVSTSISLASLEILVHIRKDTVLNQYQLFSIDIPDDQIDYLDKA
WLPEDWQENPAPVSTMDLGTGWLQASSALALILPSCIIPYENNAILNPLHPAFHTALSSVQQMPFIFDTRLAEKTAP

Nucleotide

• Length: 474 bp

>T206779 NZ_CP102679:2444505-2444612 [Escherichia coli]
ATGACGCTCGCGCAGTTTGCCATGACTTTCTGGCACGACCTGGCAGCACCGATCCTGGCGGGGATTATTACCGCAGCGAT
TGTCAGCTGGTGGCGTAACCGGAAGTAA

Antitoxin

Protein

• Length: 148 a.a.
• Molecular weight: 16365.72 Da
• Isoelectric Point: 8.5886

>AT206779 WP_045261776.1 NZ_CP077206:c1548058-1547615 [Enterobacter bugandensis]
MRTWIPAKKPADNALWRYAGLPANRGMRLIEFLNQGLPVSVLDNIHEWTAMSKADILRVTGINERNVARRKSAGRTLTPD
ESERVARFVRVLDAAVDYFGSKEEAWNWLQSPVRGLGNVAPVDLIATETGALEVTDLIGRLEHGVFA

Nucleotide

• Length: 444 bp

>AT206779 NZ_CP102679:c2444457-2444390 [Escherichia coli]
GTCTGGTTTCAAGATTAGCCCCCGTTTTGTTGTCAGGTTAAACCTCTCAACGTGCGGGGGTTTTCTCT