Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/-
Location 1133052..1133705 Replicon chromosome
Accession NZ_CP077205
Organism Acinetobacter pittii strain FDAARGOS 1398

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag I6L28_RS05475 Protein ID WP_057105658.1
Coordinates 1133316..1133705 (+) Length 130 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID A0A009HHW9
Locus tag I6L28_RS05470 Protein ID WP_002117064.1
Coordinates 1133052..1133309 (+) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
I6L28_RS05450 (I6L28_05450) 1128565..1129572 + 1008 WP_002116730.1 DNA-directed RNA polymerase subunit alpha -
I6L28_RS05455 (I6L28_05455) 1129591..1129968 + 378 WP_002049717.1 50S ribosomal protein L17 -
I6L28_RS05460 (I6L28_05460) 1130150..1131640 + 1491 WP_216947030.1 NAD(P)/FAD-dependent oxidoreductase -
I6L28_RS05465 (I6L28_05465) 1131691..1132863 - 1173 WP_216947031.1 acyl-CoA dehydrogenase family protein -
I6L28_RS05470 (I6L28_05470) 1133052..1133309 + 258 WP_002117064.1 succinate dehydrogenase assembly factor 2 Antitoxin
I6L28_RS05475 (I6L28_05475) 1133316..1133705 + 390 WP_057105658.1 hypothetical protein Toxin
I6L28_RS05480 (I6L28_05480) 1134476..1135564 + 1089 WP_014207738.1 hypothetical protein -
I6L28_RS05485 (I6L28_05485) 1135649..1136224 + 576 WP_151747806.1 rhombosortase -
I6L28_RS05490 (I6L28_05490) 1136404..1138599 + 2196 WP_016143554.1 TRAP transporter large permease subunit -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Flavinator of succinate dehydrogenase

(10-82)


Sequences

Toxin        


Download         Length: 130 a.a.        Molecular weight: 15493.44 Da        Isoelectric Point: 8.7137

>T206776 WP_057105658.1 NZ_CP077205:1133316-1133705 [Acinetobacter pittii]
MIKELSFELKYSRVSVIFQLFVGLGLAILLYQLLTAIWWLCAVILLFIGFIFFLKQAQISQIEYLDQKLWSVAYYSEKEI
YRAEIRKIIDYQMFVVIYFEGTSAKATTVWFDQLSFEQWKRLKVLEKLY

Download         Length: 390 bp

>T206776 NZ_CP102679:1793861-1793964 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 10295.73 Da        Isoelectric Point: 4.4809

>AT206776 WP_002117064.1 NZ_CP077205:1133052-1133309 [Acinetobacter pittii]
MSDEMTLEERKVIYRARRGLKEIDVYFDPYVKNYYLKADPAEKALFAELVDQEDPDLLDWFMEVSEPPRTELREFIYKLK
QYVHG

Download         Length: 258 bp

>AT206776 NZ_CP102679:c1794002-1793731 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A009HHW9

References