206741

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumA-relB/upstrm_HI1419-dnstrm_HI1420
Location 291649..292251 Replicon chromosome
Accession NZ_CP077097
Organism Pseudomonas anuradhapurensis strain RD8MR3

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag HU763_RS01305 Protein ID WP_186687554.1
Coordinates 291649..291939 (+) Length 97 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag HU763_RS01310 Protein ID WP_186687553.1
Coordinates 291949..292251 (+) Length 101 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HU763_RS01290 (HU763_001290) 287987..289372 + 1386 WP_013970487.1 GABA permease -
HU763_RS01295 (HU763_001295) 289554..289997 - 444 WP_170027848.1 hypothetical protein -
HU763_RS01300 (HU763_001300) 290519..291499 - 981 WP_225931913.1 polyphosphate kinase 2 -
HU763_RS01305 (HU763_001305) 291649..291939 + 291 WP_186687554.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
HU763_RS01310 (HU763_001310) 291949..292251 + 303 WP_186687553.1 putative addiction module antidote protein Antitoxin
HU763_RS01320 (HU763_001320) 292549..292821 - 273 WP_003257478.1 oxidative damage protection protein -
HU763_RS01325 (HU763_001325) 292818..293885 - 1068 WP_186687552.1 A/G-specific adenine glycosylase -
HU763_RS01330 (HU763_001330) 293882..296119 - 2238 WP_186687551.1 AsmA family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(1-96)

Antitoxin

Uncharacterized protein HI1420

(5-92)


Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 10961.85 Da        Isoelectric Point: 10.6219

>T206741 WP_186687554.1 NZ_CP077097:291649-291939 [Pseudomonas anuradhapurensis]
MHTLIQTETYRRWFAALRDPRAKARINVRLRRVELGVMGDCKPVAVGVSELRIDYVPGYRVYFVQRGYEVIILLAGGDKA
SQARDIKSALKLARDL

Download         Length: 291 bp

>T206741 NZ_CP102675:611508-611615 [Escherichia coli]
ATGACGCTCGCGAAGTTTGCCATGATTTTCTGGCACGACCTGGCAGCACCGATCCTGGCGGGGATTATTACCGCAGCGAT
TGTCGGCTGGTGGCGTAACCGGAAGTAA

Antitoxin


Download         Length: 101 a.a.        Molecular weight: 10739.42 Da        Isoelectric Point: 4.8307

>AT206741 WP_186687553.1 NZ_CP077097:291949-292251 [Pseudomonas anuradhapurensis]
MTDIKLSKWDAVDHFKTEEDMALYLEACLEENDPALLAAALGDIARARGMAQLARDTGLTREGLYKALSAEGNPSLATIM
KVMAALGVRLHAELLPRAAG

Download         Length: 303 bp

>AT206741 NZ_CP102675:c611455-611394 [Escherichia coli]
TGGTTCAAGATTAGCCCCCGTTCTGTTGTCAGGTTTTACCTCTCAACGTGCGGGGGTTTTCT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References