Detailed information of TA system TA206730

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): PfiT-PfiA/-
• Location: 1078741..1079312
• Replicon: chromosome
• Accession: NZ_CP077093
• Organism: Pseudomonas vanderleydeniana strain RW8P3

Toxin (Protein)

• Gene name: PfiT
• Uniprot ID: -
• Locus tag: HU752_RS04790
• Protein ID: WP_186682579.1
• Coordinates: 1078741..1079079 (-)
• Length: 113 a.a.

Antitoxin (Protein)

• Gene name: PfiA
• Uniprot ID: -
• Locus tag: HU752_RS04795
• Protein ID: WP_186682581.1
• Coordinates: 1079076..1079312 (-)
• Length: 79 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
HU752_RS04765 (HU752_004765)	1074615..1075697	-	1083	WP_186682569.1	endonuclease/exonuclease/phosphatase family protein	-
HU752_RS04770 (HU752_004770)	1075785..1076450	-	666	WP_186682571.1	YciC family protein	-
HU752_RS04775 (HU752_004775)	1076631..1077389	+	759	WP_186682573.1	DUF2076 domain-containing protein	-
HU752_RS04780 (HU752_004780)	1077588..1078067	+	480	WP_186682575.1	NYN domain-containing protein	-
HU752_RS04785 (HU752_004785)	1078096..1078707	+	612	WP_186682577.1	3'-5' exonuclease	-
HU752_RS04790 (HU752_004790)	1078741..1079079	-	339	WP_186682579.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
HU752_RS04795 (HU752_004795)	1079076..1079312	-	237	WP_186682581.1	type II toxin-antitoxin system Phd/YefM family antitoxin	Antitoxin
HU752_RS04800 (HU752_004800)	1080043..1080540	+	498	WP_186682583.1	Bro-N domain-containing protein	-
HU752_RS04805 (HU752_004805)	1080779..1081246	-	468	WP_186682585.1	Lrp/AsnC family transcriptional regulator	-
HU752_RS04810 (HU752_004810)	1081406..1082296	+	891	WP_186682587.1	drug/metabolite exporter YedA	-
HU752_RS04815 (HU752_004815)	1082368..1083705	+	1338	WP_186682589.1	DEAD/DEAH box helicase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (6-97)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 113 a.a.
• Molecular weight: 12833.40 Da
• Isoelectric Point: 5.0892

>T206730 WP_186682579.1 NZ_CP077093:c1079079-1078741 [Pseudomonas vanderleydeniana]
MTRTVFTHAAIRSIDMQELYLADKVGHQAASKYFGELEDVEQRLNDHPESGQLCLQAAELGAIQYRELNYNPYRVIYSHD
AASDTAVVHLVLNQAQNVRDWLVHYCLIKDLD

Nucleotide

• Length: 339 bp

>T206730 NZ_CP102669:4765907-4766218 [Salmonella enterica subsp. enterica serovar Typhimurium]
GTGCATGTTATCAGCCGAAAACCGTTCAATGAAGCGATGCTCATGTATCCAAACCATGAGCTTGCTCTCACTGAGTTGCT
GAATGTTCTGGAGAAAAAAACATTCACTCAGCCTGAAGAGATGAAGCGGTATATTCCTTCACTGGATAATTTTAAGTACA
GAGATAAATGGTGGGTGATTGATGTTTCTGGTAACAGCCTGAGACTCATTTCCTACATAGATTTCAGGTTACATAAGATA
TTTGTGAAACATATCGTTTCCCATGCCGAATATGACAAACTGACCGCATACTATCGGGGTAATAAAGAATGA

Antitoxin

Protein

• Length: 79 a.a.
• Molecular weight: 8987.28 Da
• Isoelectric Point: 8.4538

>AT206730 WP_186682581.1 NZ_CP077093:c1079312-1079076 [Pseudomonas vanderleydeniana]
MRVETISYLKAHASDLDLQEPMIVTQNGKPAYVVESYEDRVRRDEALALVKLLAISSREYAEGKFLTADEMRARRSRK

Nucleotide

• Length: 237 bp

>AT206730 NZ_CP102669:4766215-4766661 [Salmonella enterica subsp. enterica serovar Typhimurium]
ATGAGAACTCATCGTCAGATGGATGCAACCAGCGCAAAAAAGATCGTTGATACCTTCAGCGATGCGGTAAAAACCGTCCC
ACTGATGGGGGAAGACCGAAATGACAATGAGTATCGCAGGGCACTAGCGCTAGTGGAGTTTCTGGTCGACCACGACGATC
TTGAAAACCCACTATTTGAATTGCTCTGTGCCCGAATCAGTGAATACGAAAAACATGCGCCGGAATTCAAAGCACTCAAC
CAACACCTGGAGAAAACGCCCCCTGGCGTTTCAGTATTGCGAACGCTCATGGATCAATACGGTCTCAAAGCAGCAGATCT
TGCCAACGAACTTGGTTCTAAATCGAACGTCAGCAACATCTTAAATGGCCGCAGAGCACTAACGGTTAATCATATTAAAG
CGCTTACACAACGCTTCAAACTACCAGCAGATGCCTTCATCGAGTAG