Detailed information of TA system TA206725

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/-
• Location: 3643585..3644038
• Replicon: chromosome
• Accession: NZ_CP077092
• Organism: Pseudomonas iranensis strain SWRI54

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: HU724_RS16235
• Protein ID: WP_262137240.1
• Coordinates: 3643826..3644038 (+)
• Length: 71 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: HU724_RS16230
• Protein ID: WP_186569711.1
• Coordinates: 3643585..3643779 (+)
• Length: 65 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
HU724_RS16205 (HU724_016205)	3638788..3639585	+	798	WP_186569715.1	ATP-binding cassette domain-containing protein	-
HU724_RS16210 (HU724_016210)	3639579..3640406	+	828	WP_186569714.1	ABC transporter permease	-
HU724_RS16215 (HU724_016215)	3640403..3641170	+	768	WP_186569713.1	phosphonate ABC transporter, permease protein PhnE	-
HU724_RS16220 (HU724_016220)	3641349..3643028	+	1680	WP_186569712.1	MFS transporter	-
HU724_RS16225 (HU724_016225)	3643136..3643354	+	219	WP_042606898.1	hypothetical protein	-
HU724_RS16230 (HU724_016230)	3643585..3643779	+	195	WP_186569711.1	stability determinant	Antitoxin
HU724_RS16235 (HU724_016235)	3643826..3644038	+	213	WP_262137240.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (3-69)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 71 a.a.
• Molecular weight: 7928.34 Da
• Isoelectric Point: 12.0743

>T206725 WP_262137240.1 NZ_CP077092:3643826-3644038 [Pseudomonas iranensis]
IEQFNLRASASLLRKVGAAAQTLSSVPHGFRFGRIPGTREMVIHPNYLLVYRVNGQIRILTVIHARKKYP

Nucleotide

• Length: 213 bp

>T206725 NZ_CP102669:3809341-3809616 [Salmonella enterica subsp. enterica serovar Typhimurium]
ATGAATGCCTCCGGCGTCAGCGTCCGCCATATCAACAGCGAAACCTGCATGACCGCCTGTTACTCACAAATCCCCAGCCA
GCACCTTAAGGGTGACTGGCAGGAAGAAGCGGGATTTGAGACCGGGCACGGCGTCACCGTGAAGATCTCCGAGGGGTGTT
TGATCCTGATTGCAGAGACGGACGAAGTGAGGGATCTACGGAAGGAGCTTTATCAGGTGAAAAAGTCGATGAAGCATATT
AAGGCGGGGGTAAATAATGTGGTGAACGGGGATTAA

Antitoxin

Protein

• Length: 65 a.a.
• Molecular weight: 7259.16 Da
• Isoelectric Point: 4.5680

>AT206725 WP_186569711.1 NZ_CP077092:3643585-3643779 [Pseudomonas iranensis]
MSAELSLIVSDFETEEEAASYDLWYRAKVQAALDDPRPGIPHDEAMVILAQKIEERRKNRRAAG

Nucleotide

• Length: 195 bp

>AT206725 NZ_CP102669:c3809606-3809184 [Salmonella enterica subsp. enterica serovar Typhimurium]
TTCACCACATTATTTACCCCCGCCTTAATATGCTTCATCGACTTTTTCACCTGATAAAGCTCCTTCCGTAGATCCCTCAC
TTCGTCCGTCTCTGCAATCAGGATCAAACACCCCTCGGAGATCTTCACGGTGACGCCGTGCCCGGTCTCAAATCCCGCTT
CTTCCTGCCAGTCACCCTTAAGGTGCTGGCTGGGGATTTGTGAGTAACAGGCGGTCATGCAGGTTTCGCTGTTGATATGG
CGGACGCTGACGCCGGAGGCATTCATATTTGCTGACTAAATAAATTCTTATTTATCCGCCGGATGCTGGCTGATTGTGGA
GCTCAGGGTGAGTGAGTATGGGCGCGACATCCTGGCACCGCGCCTCCCTCTCCCCGGCCAGCCCCGGCCGGTGATGAGCA
GCCGGCTGCCGGGGCCGTATTTT