Detailed information of TA system TA206708

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/RelE(toxin)
• Location: 1736954..1737404
• Replicon: chromosome
• Accession: NZ_CP077091
• Organism: Pseudomonas hamedanensis strain SWRI65

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: HU739_RS07435
• Protein ID: WP_186552584.1
• Coordinates: 1737135..1737404 (+)
• Length: 90 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: HU739_RS07430
• Protein ID: WP_186552583.1
• Coordinates: 1736954..1737145 (+)
• Length: 64 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
HU739_RS07400 (HU739_007400)	1732301..1732990	+	690	WP_186551991.1	GNAT family protein	-
HU739_RS07405 (HU739_007405)	1732995..1734185	+	1191	WP_186551992.1	GNAT family N-acetyltransferase	-
HU739_RS07410 (HU739_007410)	1734182..1734874	+	693	WP_186551993.1	N-acetyltransferase	-
HU739_RS07415 (HU739_007415)	1735115..1735408	+	294	WP_186552580.1	type II toxin-antitoxin system RelE/ParE family toxin	-
HU739_RS07420 (HU739_007420)	1735411..1735719	+	309	WP_186552581.1	putative addiction module antidote protein	-
HU739_RS07425 (HU739_007425)	1735848..1736645	-	798	WP_186552582.1	class I SAM-dependent methyltransferase	-
HU739_RS07430 (HU739_007430)	1736954..1737145	+	192	WP_186552583.1	antitoxin	Antitoxin
HU739_RS07435 (HU739_007435)	1737135..1737404	+	270	WP_186552584.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
HU739_RS07440 (HU739_007440)	1737477..1738376	-	900	WP_186552585.1	LysR family transcriptional regulator	-
HU739_RS07445 (HU739_007445)	1738702..1740129	+	1428	WP_186552586.1	mechanosensitive ion channel family protein	-
HU739_RS07450 (HU739_007450)	1740343..1740966	-	624	WP_016774080.1	isochorismate family cysteine hydrolase YcaC	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (2-84)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 90 a.a.
• Molecular weight: 10311.80 Da
• Isoelectric Point: 9.7867

>T206708 WP_186552584.1 NZ_CP077091:1737135-1737404 [Pseudomonas hamedanensis]
MQIKWRPEAKADLSNILRYIGERNFTAAVSLSKSIEESTTSLSVHPRLYRKGRSPGTREIVVHPNYVVIYEVTDRIEILS
VLHTRQEYP

Nucleotide

• Length: 270 bp

>T206708 NZ_CP102663:c1440884-1440138 [Bacillus sp. BAC]
ATGCTGCTATTTTATCAATTCCTTGTTTGGCTTATTGTTTTGGCGCTGGCTCTGTACGTAGCTGCCGTGTGGCGTTTTGA
AAAACAGCTCGCCGAAAAAACGGTCGCCATCAGAAAAACGTGGTACCTTCTTTATGTCATCGGCGCCGTGATATATTGGA
CGCACGATCCGCAGTCAATTTTCACAAACCCGCTTCATTACCTGATCGTTGCCGTTTTTTTCACGTTGACAGACGCTTTT
ATTTTCTTAAATGCCTACTTTAAAAAGCTCGGCAGCTCTGAACTCGCGACAGATACAAGAATGCTTCTCGAAGAAAACAA
CGACCTCCTCCACACGTATCAAAACAGGCTGAAAACGTTTCAATACCTATTGAAAAACGAACCGATCCACATCTATTATG
GAAATATAGAAGCGTATGCAGAAGGCATCGAAAAGCTCATCAAACGGTTTGCCGAAAAAATGAATATATCCGCTGCACTT
TGCGAATATAATTCAGAAGAAAGCAAGGATCATTTGCTTGAGCATATGGAAAACCGGTTCGATGTTCAAGAAAAGCTTGA
CCGCAAAGACGTTTATTATGAAGAAAACGGAAAAATGGTCCTCATTCCTTTTTCCATCCACGATTTTGACTATGTCATGA
AGTTAACCTCAGAAGACCTTGTCACAGAATTTGATTATCTCCTGTTTACTTCTTTAACAAGCATCTATGATCTTCTGCTA
CCAAACGAAGAGGAAGGTGACGACTGA

Antitoxin

Protein

• Length: 64 a.a.
• Molecular weight: 7217.97 Da
• Isoelectric Point: 4.7734

>AT206708 WP_186552583.1 NZ_CP077091:1736954-1737145 [Pseudomonas hamedanensis]
MDSKIFPADSEFESEEQAASHDRWLRAKVQASRDDPRPSFAHDEVMAQMHALIESMRKKADAD

Nucleotide

• Length: 192 bp

>AT206708 NZ_CP102663:c1440138-1439965 [Bacillus sp. BAC]
ATGGAGCCTGCTTTTCAGCAAGACCAGGAAAGCGTAAAAAAGCGCCTCGCCTTTAAAATGTTTAAAAGGCAATCCAAAAC
CAATATCGCGAAATACGAAGTCAGCCCCCATACCGAACGGATTTTCCGGCAAAACGAACGGCTGATCGGCGAGTATAAAA
GAAAAAAAGCTTAA