206707

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumAB/upstrm_HI1419-dnstrm_HI1420
Location 1735115..1735719 Replicon chromosome
Accession NZ_CP077091
Organism Pseudomonas hamedanensis strain SWRI65

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag HU739_RS07415 Protein ID WP_186552580.1
Coordinates 1735115..1735408 (+) Length 98 a.a.

Antitoxin (Protein)


Gene name PumB Uniprot ID -
Locus tag HU739_RS07420 Protein ID WP_186552581.1
Coordinates 1735411..1735719 (+) Length 103 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HU739_RS07395 (HU739_007395) 1730313..1732232 + 1920 WP_186551990.1 hypothetical protein -
HU739_RS07400 (HU739_007400) 1732301..1732990 + 690 WP_186551991.1 GNAT family protein -
HU739_RS07405 (HU739_007405) 1732995..1734185 + 1191 WP_186551992.1 GNAT family N-acetyltransferase -
HU739_RS07410 (HU739_007410) 1734182..1734874 + 693 WP_186551993.1 N-acetyltransferase -
HU739_RS07415 (HU739_007415) 1735115..1735408 + 294 WP_186552580.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
HU739_RS07420 (HU739_007420) 1735411..1735719 + 309 WP_186552581.1 putative addiction module antidote protein Antitoxin
HU739_RS07425 (HU739_007425) 1735848..1736645 - 798 WP_186552582.1 class I SAM-dependent methyltransferase -
HU739_RS07430 (HU739_007430) 1736954..1737145 + 192 WP_186552583.1 antitoxin -
HU739_RS07435 (HU739_007435) 1737135..1737404 + 270 WP_186552584.1 type II toxin-antitoxin system RelE/ParE family toxin -
HU739_RS07440 (HU739_007440) 1737477..1738376 - 900 WP_186552585.1 LysR family transcriptional regulator -
HU739_RS07445 (HU739_007445) 1738702..1740129 + 1428 WP_186552586.1 mechanosensitive ion channel family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(4-96)

Antitoxin

Uncharacterized protein HI1420

(4-93)


Sequences

Toxin        


Download         Length: 98 a.a.        Molecular weight: 10627.17 Da        Isoelectric Point: 10.9839

>T206707 WP_186552580.1 NZ_CP077091:1735115-1735408 [Pseudomonas hamedanensis]
MTYLIQQTATFQAWHRSIRDLRAKVAIARRIDRASTGNLGDAKSVGDGVSEMRLDVGAGYRVYFTIRNGAVIVLLAGGDK
SSQSADIRRAQKMAKEV

Download         Length: 294 bp

>T206707 NZ_CP102663:564995-565345 [Bacillus sp. BAC]
TTGATTGTTAAACGCGGCGATGTTTATTTTGCTGACCTATCTCCTGTTGTTGGCTCAGAACAAGGCGGGGTGCGCCCGGT
TTTAGTGATTCAAAACAACATCGGCAATCGCTTCAGCCCAACTGCTATTGTTGCAGCCATAACAGCCCAAATACAGAAAG
CAAAATTACCTACCCACGTCGAAATTGATGCGAAACGCTACGGTTTTGAAAGAGACTCCGTTATATTGCTCGAACAAATT
CGGACGATTGACAAGCAAAGATTAACGGACAAAATCACCCATCTCGATGATGAAATGATGGAAAAGGTCAACGAAGCCTT
ACAAATCAGTTTGGCACTCATTGATTTTTAA

Antitoxin


Download         Length: 103 a.a.        Molecular weight: 11028.56 Da        Isoelectric Point: 5.5648

>AT206707 WP_186552581.1 NZ_CP077091:1735411-1735719 [Pseudomonas hamedanensis]
MSQTLTNFDMVALLDSDEAISEYLSQVLADGDSEEFLRAIGYVLRARGMTQIAKNSGMGRESLYKAFAPGAKPRFDTVLK
VIHALGIDLCAQPGHGINHSVS

Download         Length: 309 bp

>AT206707 NZ_CP102663:564709-564990 [Bacillus sp. BAC]
TTGTCTGAATCCAGCGCAACAACTGAAATATTGATTCGCTTGCCAGAAGCTTTAGTATCAGAACTGGATGGTGTCGTCAT
GCAAGATAACGGGAGCAGAAATGAACTGATTTACCAAGCCACAAAAATGTATTTACGCGAACGCAAAAATCGACAAATTC
GGGAATCGATGAGACGCGGTTATATGGAGATGGCCAAGATCAATTTGAACATCTCTTCTGAGGCTCAATTTGCAGAGTAT
GAGGCTGAAAACACAGTAGAGCGCTTAGTAAGCGGAGGATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References