206702

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) hicAB/HicA-HicB
Location 1835572..1836201 Replicon chromosome
Accession NZ_CP077090
Organism Pseudomonas zeae strain OE 48.2

Toxin (Protein)


Gene name hicA Uniprot ID -
Locus tag HU754_RS08150 Protein ID WP_186623815.1
Coordinates 1836016..1836201 (-) Length 62 a.a.

Antitoxin (Protein)


Gene name hicB Uniprot ID -
Locus tag HU754_RS08145 Protein ID WP_186623803.1
Coordinates 1835572..1835979 (-) Length 136 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HU754_RS08120 (HU754_008120) 1831126..1831896 + 771 WP_186623799.1 trans-aconitate 2-methyltransferase -
HU754_RS08125 (HU754_008125) 1832119..1832847 - 729 WP_186623801.1 class I SAM-dependent methyltransferase -
HU754_RS08130 (HU754_008130) 1833420..1833782 + 363 WP_093438463.1 DUF6124 family protein -
HU754_RS08135 (HU754_008135) 1833859..1835118 - 1260 WP_150773831.1 type II toxin-antitoxin system HipA family toxin -
HU754_RS08140 (HU754_008140) 1835111..1835428 - 318 WP_095119135.1 helix-turn-helix transcriptional regulator -
HU754_RS08145 (HU754_008145) 1835572..1835979 - 408 WP_186623803.1 type II toxin-antitoxin system HicB family antitoxin Antitoxin
HU754_RS08150 (HU754_008150) 1836016..1836201 - 186 WP_186623815.1 type II toxin-antitoxin system HicA family toxin Toxin
HU754_RS08160 (HU754_008160) 1836636..1837520 - 885 WP_186623805.1 alpha/beta hydrolase -
HU754_RS08165 (HU754_008165) 1837837..1838529 - 693 WP_186623807.1 16S rRNA pseudouridine(516) synthase -
HU754_RS08170 (HU754_008170) 1838563..1838793 - 231 WP_064119704.1 cysteine-rich CWC family protein -
HU754_RS08175 (HU754_008175) 1838786..1840273 - 1488 WP_186623809.1 sensor domain-containing diguanylate cyclase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

HicA mRNA interferase family

(11-59)

Antitoxin

HicB-like antitoxin of toxin-antitoxin system

(3-128)


Sequences

Toxin        


Download         Length: 62 a.a.        Molecular weight: 6735.94 Da        Isoelectric Point: 11.4934

>T206702 WP_186623815.1 NZ_CP077090:c1836201-1836016 [Pseudomonas zeae]
IDHKSQVGIGQLVADGWSLVRVRGSHHHFKQPVKPGQVTVPHPKKNLLKKTAISILQQALL

Download         Length: 186 bp

>T206702 NZ_CP102605:c911754-911425 [Pantoea sp. SOD02]
ATTAGCTATCTGGAGTTTATCGAAACTCGCGTTTTCTCTAAGGCGCGCAAAGTATTGCTTGAAGATGATGACGAATTTAA
CGAATTACAGTGTTATTTACTCGATCACCACGATTTAGGTGACACGATTAGAGATACCGGCGGTTGTAAGAAAATCCGTT
GGAGTCGTTCAGGCATGGGCAAGCAAGGTGGCACACGGATTATTTATTTCACCAGACTGCTGTCGGGAAGAATTTATTTA
CTGCTCATCTATCCTAAAAACGTTAAAGACGATTTAAATGAGAATGAAAAGGCGATGCTTAAAGTTTTCACAAGGCAAAT
CAATTTGTAA

Antitoxin


Download         Length: 136 a.a.        Molecular weight: 14442.46 Da        Isoelectric Point: 4.4904

>AT206702 WP_186623803.1 NZ_CP077090:c1835979-1835572 [Pseudomonas zeae]
MLYPIAISIGDEEHAWGVEVPDIPGCFSAGDDLDDAVAMAREAIEGHFEILAEDGAPIPPASKLGVNVANPKYAGCAWAV
VDIDVVKYLGKAQKLNITLPGHLLNRIDEYVLHHPEEKSRSGFLASAALKVLQQG

Download         Length: 408 bp

>AT206702 NZ_CP102605:c911396-911100 [Pantoea sp. SOD02]
ATGGACAAAAAACTGTTTAACGATTTACTTGAAAGCATGCAGGAGATGGTCGCGATTGAGAAAGGACAAGAAATCCCTGA
AACAAGCCGCGTCCATCGTCATGCGCTACCCGATGTAAAACTCATCAGAAAAAATGCGGGTCTTAAACAAGCTGAGTTTG
CTGATGCGATGGGTGTCAGTGTGGATTTGATTCGCAGCTGGGAGCAGCAGCGCCGAAACCCAACAGGGCCAGCCCTAAAA
ATGCTTTATTTGATTGAACAGCAGCCACTTTTGATTAACGCGCTACGAGCAATCTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References