Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE-RHH
Location 1824886..1825399 Replicon chromosome
Accession NZ_CP077090
Organism Pseudomonas zeae strain OE 48.2

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag HU754_RS08070 Protein ID WP_186623775.1
Coordinates 1824886..1825170 (-) Length 95 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag HU754_RS08075 Protein ID WP_186623784.1
Coordinates 1825160..1825399 (-) Length 80 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HU754_RS08055 (HU754_008055) 1820997..1822190 + 1194 WP_186623769.1 CaiB/BaiF CoA-transferase family protein -
HU754_RS08060 (HU754_008060) 1822187..1823113 + 927 WP_186623771.1 hydroxymethylglutaryl-CoA lyase -
HU754_RS08065 (HU754_008065) 1823299..1824630 + 1332 WP_186623773.1 MFS transporter -
HU754_RS08070 (HU754_008070) 1824886..1825170 - 285 WP_186623775.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
HU754_RS08075 (HU754_008075) 1825160..1825399 - 240 WP_186623784.1 ribbon-helix-helix protein, CopG family Antitoxin
HU754_RS08080 (HU754_008080) 1825582..1826310 + 729 WP_186623786.1 hypothetical protein -
HU754_RS08085 (HU754_008085) 1826340..1827065 + 726 WP_186623788.1 hypothetical protein -
HU754_RS08090 (HU754_008090) 1827070..1827486 + 417 WP_099758231.1 fosfomycin resistance glutathione transferase -
HU754_RS08095 (HU754_008095) 1827546..1828184 + 639 WP_186623790.1 LysE family translocator -
HU754_RS08100 (HU754_008100) 1828264..1829613 + 1350 WP_186623793.1 diguanylate cyclase -
HU754_RS08105 (HU754_008105) 1829730..1829885 + 156 WP_007911485.1 KGG domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(2-83)

Antitoxin

Ribbon-helix-helix protein, CopG

(5-41)


Sequences

Toxin        


Download         Length: 95 a.a.        Molecular weight: 11013.73 Da        Isoelectric Point: 10.8700

>T206701 WP_186623775.1 NZ_CP077090:c1825170-1824886 [Pseudomonas zeae]
MRVEWLKTALKNLDDEAAYIALDNPKAASEFVQAIFANVDHLTRFPSSGREGRLPGTREWVVPDRPYLIPYRVRQSRLQV
LRIFHTRRLPPKAW

Download         Length: 285 bp

>T206701 NZ_CP102604:c4222174-4220855 [Pantoea sp. SOD02]
ATGACAGAATTGGATGTCTATATGAACGGCTACAAGGTGGGTATTTTCGCGCGAGCCGCAACGGGCGCCCATCAGTTTTG
CTACTTAGAAGAGTGGTTAAACCAACCGGGAAGCCGCCCTATTTCTCTTTCAATGCCGTTACGCCATCCACCCTATACAG
GCAGTGAAGTCTACAACTTCTTCGATAACCTACTGCCAGACAATATCGAAATTCGTAATAGAATTCTCACTCGACACCAA
GCTGAATCCAGTCAACAATTTGATTTATTGTATAAAATTGGCGCAGATACTGTTGGAGCATTACAGCTGCTGGCTCATGA
CTCGCCTCCACGTGATGTGCAATCAATACACTATAAAGCGCTCGATGATGCTGAACTTGAGAAGATCCTAACCGGCTATC
AAGCTGGCGCACCGCTCGGCATGATCGAAGAAATTGATGACTTCAGAATTTCACTGGCAGGTGCGCAGGAAAAAACCGCG
TTATTACGCATCAACGATAAATGGTGTCTGCCGCAAGGTACAACCCCCACAACGCATATCCTCAAACTGCCAATTGGTAA
AATTCAGAGCCACTCTTACAGCATTGATCTCACGGGAAGCGTGGAGAATGAGTGGCTTTGTACATTAATTGCTAAAGAGT
TTGGCTTATCTGTGCCCGATTGCTTCATTGTTCGTGTAGGCGACGTTAAGGCGCTGGCGGTAGAGAGATTCGATCGTAAA
TATGCGGCAGATGGCAGCTGGATCATGCGGTTACCGCAAGAGGATTTTTGCCAGGTATTGAATGTACCTGCGGCCGCTAA
ATATGAAACCCAGGGCGGACCCGGTATCGCGCAAATAATGGACTATCTGCTGAGTTCAGTCGCAGTAGAGCAAGATCGCT
ACGACTTCATGAAGGCGCAAGTATTATTCTGGCTGCTGGCCGCAACAGATGGACATGCTAAAAATTTCTCCATCTTTATT
GAAGCCGAAGGTCGTTTTCGCCTGGCGCCTTTTTACGACATCCTCTCCGTCTATCCCATGATTGGCGGCAAAGGGTTAAA
TATTCGCGATGCAAAATTGGCAATGGGACTAAAAGGAAGCAAAGGCAAAAAGTATGCGGTTGAGCAAATTTTCCCACGCC
ATTTTATTGAGACCGCCAAAGCAGTCGGATTTGATCCTGCTGCCATGCAACGTGTTCTGCGTGAATTAAGCGAAAGCGTG
GATGATGTTATTGAGCGCGTGTGCCAACAGCTTCCGGAAGATTTTCCTCCCTCTATCCAGGCCACCATTCTTGATGGTCT
TAAGATGCGTGCAACACGCTTGAAACCAGAACAAGACTAA

Antitoxin


Download         Length: 80 a.a.        Molecular weight: 8755.83 Da        Isoelectric Point: 4.3449

>AT206701 WP_186623784.1 NZ_CP077090:c1825399-1825160 [Pseudomonas zeae]
MSVMSLRIPDEIADTLANLAKATGRTKSYLAVDALREYLAREAWQIEEIQKALKEADAGDFATDEEVRAIAEKWNANAS

Download         Length: 240 bp

>AT206701 NZ_CP102604:c4222434-4222174 [Pantoea sp. SOD02]
ATGAAAATCACCAATGCCAAACAATTGAGTGCATATCTCAAGGACGTAAGACAGTCTGAGCACCTTTCCCAGGGAAAAGT
GGCCAACAAAGTGGGGATCCGGCAAGACACGGTCTCTAATTTTGAACTGCAACCCGGCACCACAAAACTCGATACGTTCT
TTCGCATTCTCGCCGCCTTGAATTTAGAACTGGAGATAAAACCGCGCGGCAATTCCGATCACACCCAGCAAAAGAGTAGC
GGCTGGAAGGAGGAGTGGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References