Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/-
Location 2988518..2989764 Replicon chromosome
Accession NZ_CP077085
Organism Pseudomonas shahriarae strain SWRI52

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag HU773_RS13355 Protein ID WP_186625930.1
Coordinates 2989183..2989764 (+) Length 194 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag HU773_RS13350 Protein ID WP_057959728.1
Coordinates 2988518..2989075 (+) Length 186 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HU773_RS13325 (HU773_013325) 2983734..2984129 - 396 WP_057959733.1 hypothetical protein -
HU773_RS13330 (HU773_013330) 2984522..2984911 + 390 WP_120732971.1 MerR family transcriptional regulator -
HU773_RS13335 (HU773_013335) 2984877..2985857 - 981 WP_169990097.1 NAD-dependent epimerase/dehydratase family protein -
HU773_RS13340 (HU773_013340) 2986030..2986569 + 540 WP_057959730.1 adenylate kinase -
HU773_RS13345 (HU773_013345) 2986747..2988360 + 1614 WP_057959729.1 methyl-accepting chemotaxis protein -
HU773_RS13350 (HU773_013350) 2988518..2989075 + 558 WP_057959728.1 helix-turn-helix transcriptional regulator Antitoxin
HU773_RS13355 (HU773_013355) 2989183..2989764 + 582 WP_186625930.1 HD domain-containing protein Toxin
HU773_RS27420 2989761..2989895 - 135 WP_225923873.1 helix-turn-helix domain-containing protein -
HU773_RS27425 2990129..2990349 + 221 Protein_2637 hypothetical protein -
HU773_RS13365 (HU773_013365) 2990412..2991266 + 855 WP_057959726.1 EamA family transporter -
HU773_RS13370 (HU773_013370) 2991539..2992024 + 486 WP_057959725.1 ATP-binding protein -
HU773_RS13375 (HU773_013375) 2992076..2993242 - 1167 WP_186625929.1 MFS transporter -
HU773_RS13380 (HU773_013380) 2993337..2994230 + 894 WP_120732986.1 LysR substrate-binding domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

5'-deoxynucleotidase YfbR/HDDC2

(9-150)

Antitoxin

Cro/C1-type helix-turn-helix domain

(12-64)


Sequences

Toxin        


Download         Length: 194 a.a.        Molecular weight: 21879.83 Da        Isoelectric Point: 4.7722

>T206690 WP_186625930.1 NZ_CP077085:2989183-2989764 [Pseudomonas shahriarae]
MDIEKIKGRLEFLREAEKLKDVLRSAHTSCGRTESTAEHSWRLCLMAIVFGDYLTDLDRLKMLKMCVIHDLGEAINGDVP
AVNQDSFPNKSEQERNDLLLLTSALDEPLKAEILALWDDYENASSPEAVAVKALDKLETMLQHNQGKNPTGFDYEFNLAY
GKKYTDAAPLFEVLRTIIDQETKEHILANSKNH

Download         Length: 582 bp

>T206690 NZ_CP102594:c4575066-4574914 [Xanthomonas sp. CFBP 8445]
ATGAAGCGACTGACCACCCTGTTGATGCTGACCCTGTTCTGCGCTGGCGTGCTGACCGGCTGCAACACCGTTGCCGGCGC
CGGCAAGGACATGCAGAAGGCGGGCGAGAAGGTGGAAGACAAGGCGCAGGATTGCAGCGCTGGCAAGTGCTGA

Antitoxin


Download         Length: 186 a.a.        Molecular weight: 20669.08 Da        Isoelectric Point: 9.5912

>AT206690 WP_057959728.1 NZ_CP077085:2988518-2989075 [Pseudomonas shahriarae]
MSDMLLSPVLPGVMLRRWRLLHRVKQSHAAELFNVTQSTISRWESGVLELDPLAHKKLEQLLAARLTTAADKALGRMVRE
SSRPVHLMCDLTHRLLACSPSRAAQFTSPVSELLGRSLWRFATPNIISTELALDKLGWREAFAPPALEFLTGDNNSSIVP
ISQSLCRWTRMPLCDGTTARLVESL

Download         Length: 558 bp

>AT206690 NZ_CP102594:c4574860-4574726 [Xanthomonas sp. CFBP 8445]
ATGAAGCGTACATTTGCGTGGATGCTGCTGGCGATGTTCTCGGTGGGCCTGCTGTCCGGCTGCAACACCGTTGCCGGTGC
CGGCAAGGACGTGCAGAAGGCGGGCGAGAAGGTCGAAGACGCTGCCAAGAACTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References