Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) phd-doc/HTH_IclR(antitoxin)
Location 117501..119209 Replicon chromosome
Accession NZ_CP077085
Organism Pseudomonas shahriarae strain SWRI52

Toxin (Protein)


Gene name doc Uniprot ID -
Locus tag HU773_RS00540 Protein ID WP_186626152.1
Coordinates 117501..118379 (+) Length 293 a.a.

Antitoxin (Protein)


Gene name phd Uniprot ID -
Locus tag HU773_RS00545 Protein ID WP_057440549.1
Coordinates 118376..119209 (+) Length 278 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HU773_RS00515 (HU773_000515) 113509..114345 + 837 WP_057440627.1 ABC transporter ATP-binding protein -
HU773_RS00520 (HU773_000520) 114385..115377 + 993 WP_057961189.1 ABC transporter substrate-binding protein -
HU773_RS00525 (HU773_000525) 115406..116179 + 774 WP_057440547.1 ABC transporter permease -
HU773_RS00530 (HU773_000530) 116179..116943 + 765 WP_115129446.1 SDR family oxidoreductase -
HU773_RS00535 (HU773_000535) 116957..117496 + 540 WP_029289969.1 cupin domain-containing protein -
HU773_RS00540 (HU773_000540) 117501..118379 + 879 WP_186626152.1 alpha/beta hydrolase Toxin
HU773_RS00545 (HU773_000545) 118376..119209 + 834 WP_057440549.1 IclR family transcriptional regulator Antitoxin
HU773_RS00550 (HU773_000550) 119211..120008 + 798 WP_186626153.1 SDR family oxidoreductase -
HU773_RS00555 (HU773_000555) 120001..121683 + 1683 WP_057440551.1 thiamine pyrophosphate-binding protein -
HU773_RS00560 (HU773_000560) 121694..122497 + 804 WP_057444232.1 aspartate dehydrogenase -
HU773_RS00565 (HU773_000565) 122508..124001 + 1494 WP_057440552.1 aldehyde dehydrogenase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Alpha/beta hydrolase fold-1

(45-276)

Antitoxin

Transcription regulator IclR, N-terminal

(19-68)


Sequences

Toxin        


Download         Length: 293 a.a.        Molecular weight: 30911.36 Da        Isoelectric Point: 8.0087

>T206685 WP_186626152.1 NZ_CP077085:117501-118379 [Pseudomonas shahriarae]
MLPGLTHAAPTADLQAQLQRDFPQQRVASAGGQQALRVCGTGPAVVLLHGIGSGAASWLQVAQHLAAQARVIAWDAPGYG
DSSPLESQVPKAEQYAARLVQMLDALEVDECALVGHSLGALTALALARSAQARRVSRLVLISPARGYGAPERNAQRQQVR
QQRLDNLQRLGIAGLAEQRSAHMLSPSAQPQALAWVHWNMARLNPLGYRQAIELLCGDDLLRHGQPAMPCEVHCGEADSI
TPPDTCLGVAKALGASFNLIADAGHASPIEQPLVVAGRLAYALKQSLTGRTL

Download         Length: 879 bp

>T206685 NZ_CP102593:c4789005-4788811 [Xanthomonas campestris pv. phormiicola]
ATGCCCCCCAAAATCCGCGACGTGCTGCAACAACTCAGGGACGCAGGCTGGCAGCAAGTCAGCCAGACCGGCAGCCACCG
CCAGTTCAAGCATCCTGTCTACCCAGGCCGCGTGACAGTGGCCGGCAAGCCGAGCGATGATGTGGCTCCCGGCACCCTGA
ACAGCATTCTCAAACAGGCCGGCCTGAAGAGGTAA

Antitoxin


Download         Length: 278 a.a.        Molecular weight: 30792.26 Da        Isoelectric Point: 6.4976

>AT206685 WP_057440549.1 NZ_CP077085:118376-119209 [Pseudomonas shahriarae]
MNDSDLLKDAQDKYIVPGLERGLLLLCEFSRRNRTLTAPELARRLALPRSTIFRLLTTLETMGFVTRSGNEYRLGMSVLR
LGFEYLASLELTELGQPLLARLCDRVNYPSNLVVRDGRSIVYVAKVSPPSVFSNAVNVGTRLPAHATVLGRILLEDLSLA
ELRELYPEEHLEQHSHCTPKTVMELFDMLQADRQRGFVSGEGFFESAISTVAAPVRDQSGDIVAALGVTIPTTQIGHVNF
EELLNQVRRSADELSRLLNYNGGAHSGQPRVTALMRD

Download         Length: 834 bp

>AT206685 NZ_CP102593:c4788805-4788593 [Xanthomonas campestris pv. phormiicola]
ATGCGCTACGCCGTTGTCATTGAGCAAGCGGGTAACAACTACTCCGCCTACGTGCCGGATCTGCCGGGGTGTGTGGCGAC
GGGTGCGACGACTGCGGAGGTGGAAGATTTGATCCGCGAGGCGATCGAGTTGCATCTGGCTGGCATGCGAGAGGATGGGG
AAGTGATTCCGCTGCCTTCGAGTCAAGTTGAGTATGTGGATGTGGCGGCTTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References