Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PP_4151-4152/excise(antitoxin)
Location 5331189..5332231 Replicon chromosome
Accession NZ_CP077084
Organism Pseudomonas tritici strain SWRI145

Toxin (Protein)


Gene name PP_4152 Uniprot ID A0A8I0D0Q9
Locus tag HU722_RS24315 Protein ID WP_065890006.1
Coordinates 5331189..5331764 (-) Length 192 a.a.

Antitoxin (Protein)


Gene name PP_4151 Uniprot ID A0A8H9Z248
Locus tag HU722_RS24320 Protein ID WP_065890007.1
Coordinates 5331761..5332231 (-) Length 157 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HU722_RS24290 (HU722_0024290) 5327914..5328879 - 966 WP_083213941.1 FecR domain-containing protein -
HU722_RS24295 (HU722_0024295) 5328876..5329412 - 537 WP_065874510.1 sigma-70 family RNA polymerase sigma factor -
HU722_RS24300 (HU722_0024300) 5329581..5329910 + 330 WP_065874509.1 hypothetical protein -
HU722_RS24305 (HU722_0024305) 5329917..5330552 - 636 WP_065890004.1 LysE family translocator -
HU722_RS24310 (HU722_0024310) 5330696..5331067 + 372 WP_065874507.1 PH domain-containing protein -
HU722_RS24315 (HU722_0024315) 5331189..5331764 - 576 WP_065890006.1 PIN domain-containing protein Toxin
HU722_RS24320 (HU722_0024320) 5331761..5332231 - 471 WP_065890007.1 helix-turn-helix domain-containing protein Antitoxin
HU722_RS24325 (HU722_0024325) 5332426..5333577 + 1152 WP_065890009.1 colicin E3/pyocin S6 family cytotoxin -
HU722_RS24330 (HU722_0024330) 5333585..5333842 + 258 WP_065874503.1 colicin E3-like toxin immunity protein -
HU722_RS24335 (HU722_0024335) 5333867..5334490 + 624 WP_065880741.1 DUF3916 domain-containing protein -
HU722_RS24340 (HU722_0024340) 5334741..5335028 + 288 WP_065890011.1 colicin E3-like toxin immunity protein -
HU722_RS24345 (HU722_0024345) 5335045..5335488 + 444 Protein_4825 hypothetical protein -
HU722_RS24350 (HU722_0024350) 5335544..5336119 - 576 WP_065890013.1 hypothetical protein -
HU722_RS24355 (HU722_0024355) 5336199..5336582 - 384 WP_065874499.1 cytochrome c family protein -
HU722_RS24360 (HU722_0024360) 5336758..5337138 + 381 WP_065874498.1 response regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(9-115)

Antitoxin

Helix-turn-helix domain, group 17

(84-132)


Sequences

Toxin        


Download         Length: 192 a.a.        Molecular weight: 21585.90 Da        Isoelectric Point: 5.0408

>T206684 WP_065890006.1 NZ_CP077084:c5331764-5331189 [Pseudomonas tritici]
MRCSPFTAVYDACVLYPAALRDLLMWLGLSGLYRARWTRQIHEEWKRNVLKNRPDLTPDRVNNISALMDKAIPDALVTGY
EDLCSSLDLPDPDDRHVLAAAIRSKAEVIVTFNLKDFPAHVLAGYDIEPMHPDDFISDLWDLDQAAVLAAAQKQRRALAR
PSMDGEGYLEMLMRQGLVQTSKVLGPYEIML

Download         Length: 576 bp

>T206684 NZ_CP102593:4526700-4527356 [Xanthomonas campestris pv. phormiicola]
ATGGCGTACGACTACAAGAGGCTCATTAACCCTGAGCGGGCTCTGATCTTTCGGATCTTGCATCGGGACAACTTGACCTG
GGCACTTGACAACGGACTCCATTGCGGCAATAGCTCAGTGCTTGCTCCGGGGTGGGTGAGCATTGGCAATCCCGATTTGA
TCACTAAGCGTAGCTCCCACCCGGTCTCAATTGCGCCGGGAGGATTCCTGAACGACTACGTGCCCTTCTATTTCACTCCG
TTCTCGCCAATGCTCCGCAATATCAGCACAGGTTGGGGAGGCGTACCAAGACGGCCCAATGAAGAAATCGTGATCCTGGC
ATCAAGTTTGCTCAGGGTAGCCGCTGACGGGCTTCGCTGGGCGTTTACCGACATGCACGCTTACTATAGGTGGGCGACCT
ACTACAATGACCTTGGCAGCCTCAGTAAAATCGATTGGCCTCTTTTGCAGCGACGTGATTTCAAGCGTGACCCCGACGAC
CCCGCTAAGTTCGAGCGCTACCAAGCGGAAGCTCTGGTCCACCGCCACATGCCCCTCTCATCGCTGACAGGCATTGCATG
CTACACAGCACAAATGCAACAGGTCATTGAACAGCAAGTGCATAGCCGCGGCCTCAATTTCCCTGTTAAAGCACTACCTA
GTTGGTATTTCTCATGA

Antitoxin


Download         Length: 157 a.a.        Molecular weight: 17662.33 Da        Isoelectric Point: 6.0148

>AT206684 WP_065890007.1 NZ_CP077084:c5332231-5331761 [Pseudomonas tritici]
MITNHLPKTILPLEKEVEAAVQGQRELASLLSTKFETQRIDIFDKEDKPHTLVLPTSALRLLVDILGELAIGNAVKVVPV
HAELTSQEAADLLNVSRPHLVKMLEEGAIPFTKTGRHRRIRFSDLMAFKQRRDQESQDAMEELVRQTRELGLGYDE

Download         Length: 471 bp

>AT206684 NZ_CP102593:4527353-4528432 [Xanthomonas campestris pv. phormiicola]
ATGATCAAGTTCACACAAGGCAACCTACTGGAGGTTCCCGCAGAGGCCCTCGTCAATACAGTGAACACTGTTGGAGTGAT
GGGGAAAGGCATCGCCCTCATGTTCAAGGAGCGTTTTCCAGAAAATTTCCGTCGCTATGCAGCTGCGTGCAAAGCAGGGG
ATGTACATGTGGGCAAGATGTTTGTCACGGAGGTGTCAGAGCTAGACGGCCCCCGTTGGGTAGTGAATTTCCCTACCAAG
CAGCATTGGAGAGCGGCATCACGATTGGAGTGGATAACGGAGGGTTTACAAGAACTTCGTCACTTTCTAATCGAAAACAA
AGTCAAGTCCGTAGCGATACCTCCGCTGGGCGCAGGAAATGGTGGACTGGAATGGGCTCTCGTACGGCCTCAGATTGAGG
CGGCGCTGGGTGATCTCAGCTTGGATGTCCTAGTGTTCGAGCCAACTTCTAAATACCAGAACGTCGCCAAGCGCGCCGGT
GTGGAGAAACTAACCCCAACTCGGGCGCTCATCGCGGAGTTGGTGCGGCGTTACTGGGTTCTTGGTATGGATTGCAGTTT
GCTTGAGATCCAAAAGTTGGCATGGTTTCTTGAGAGAGCAGTCGGCCGACTCATGCCGGGGAAAGATCTGGAACTGCATT
TCGTCGCACACAAGTATGGTCCGTACGCGAATCGGCTGGATCATCTATTGAACAACTTAGACGGGAGCTACCTGCACTGC
GATAAGCGCATCAGCGATGCCGATCCCTTCGACGTCATCTGGTTCGACGAGAGCAGGAAGGATTTCCTTCAGGCTTATCT
TCGCTCTGAGGCCAAGTCATATGTGCCTGCTCTCGAGGCAACTGCTCAGCTGATTGATGGATTTGAGTCGCCATTCGGCA
TGGAGCTGCTAGCGAGCGTGGACTGGCTCCTTTTCAAAGAAGGTGTTGAGCCCACCGTTCCCGCCGTCAGGGCAGGGTTG
AAGAACTGGCAGGAAGGTAGTGGGGCCGCTGAGAGAAAAAATCGGCTCTTTGATGATCAAGCACTTAGTTTCGCGCTTGA
ACGTCTTCAGTTGAAAAAAGAAATGCACGCTCTAATGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References