Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | relBE/ParE-RelB |
Location | 5171699..5172221 | Replicon | chromosome |
Accession | NZ_CP077083 | ||
Organism | Pseudomonas salmasensis strain SWRI126 |
Toxin (Protein)
Gene name | relE | Uniprot ID | - |
Locus tag | HU731_RS23230 | Protein ID | WP_186605787.1 |
Coordinates | 5171699..5171992 (-) | Length | 98 a.a. |
Antitoxin (Protein)
Gene name | relB | Uniprot ID | A0A7Y1LCT8 |
Locus tag | HU731_RS23235 | Protein ID | WP_020301039.1 |
Coordinates | 5171982..5172221 (-) | Length | 80 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
HU731_RS23200 (HU731_023200) | 5167092..5167652 | - | 561 | WP_003189463.1 | glycine cleavage system protein R | - |
HU731_RS23205 (HU731_023205) | 5167915..5168793 | + | 879 | WP_014717368.1 | 4-hydroxy-tetrahydrodipicolinate synthase | - |
HU731_RS23210 (HU731_023210) | 5168811..5169926 | + | 1116 | WP_186605777.1 | outer membrane protein assembly factor BamC | - |
HU731_RS23215 (HU731_023215) | 5169931..5170689 | + | 759 | WP_186605779.1 | MBL fold metallo-hydrolase | - |
HU731_RS23220 (HU731_023220) | 5170717..5171430 | + | 714 | WP_027604309.1 | phosphoribosylaminoimidazolesuccinocarboxamide synthase | - |
HU731_RS23230 (HU731_023230) | 5171699..5171992 | - | 294 | WP_186605787.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
HU731_RS23235 (HU731_023235) | 5171982..5172221 | - | 240 | WP_020301039.1 | type II toxin-antitoxin system RelB/DinJ family antitoxin | Antitoxin |
HU731_RS23240 (HU731_023240) | 5172864..5173115 | + | 252 | WP_057701154.1 | hypothetical protein | - |
HU731_RS23245 (HU731_023245) | 5173188..5174414 | - | 1227 | WP_056791672.1 | MFS transporter | - |
HU731_RS23250 (HU731_023250) | 5174552..5175493 | - | 942 | WP_186605789.1 | LysR family transcriptional regulator | - |
HU731_RS23255 (HU731_023255) | 5175650..5176966 | + | 1317 | WP_186605791.1 | MFS transporter | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
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Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 98 a.a. Molecular weight: 11680.51 Da Isoelectric Point: 10.2570
>T206678 WP_186605787.1 NZ_CP077083:c5171992-5171699 [Pseudomonas salmasensis]
MTYSLDFDARALKEWQKLGDTLRQQLKKKLVEILNNPRIEANRLHRLPDCYKIKLRSSGYRLVYQVIEQEITVFVVAVDK
RERDQAYRKASERLEQR
MTYSLDFDARALKEWQKLGDTLRQQLKKKLVEILNNPRIEANRLHRLPDCYKIKLRSSGYRLVYQVIEQEITVFVVAVDK
RERDQAYRKASERLEQR
Download Length: 294 bp
>T206678 NZ_CP102592:445537-445689 [Xanthomonas sp. CFBP 8443]
ATGAAGCGACTGCTCACCTTGATGATGCTGACCCTGTTCTGTGCGGGCATGCTGACTGGCTGCAACACCATGGCCGGTGC
CGGCAAAGACATGCAGAAGGCGGGCGAGAAGGTGGAAGACAAGGCGGGCGATTGCAGCGACGGCAAGTGCTGA
ATGAAGCGACTGCTCACCTTGATGATGCTGACCCTGTTCTGTGCGGGCATGCTGACTGGCTGCAACACCATGGCCGGTGC
CGGCAAAGACATGCAGAAGGCGGGCGAGAAGGTGGAAGACAAGGCGGGCGATTGCAGCGACGGCAAGTGCTGA
Antitoxin
Download Length: 80 a.a. Molecular weight: 9027.43 Da Isoelectric Point: 4.6017
>AT206678 WP_020301039.1 NZ_CP077083:c5172221-5171982 [Pseudomonas salmasensis]
MASINIRIDDDLKTRAYLELEKLGVTPSELIRQALQYVAERGQLPFKPVLMTEEDEALMATVRERLASPQRVRVSLDDL
MASINIRIDDDLKTRAYLELEKLGVTPSELIRQALQYVAERGQLPFKPVLMTEEDEALMATVRERLASPQRVRVSLDDL
Download Length: 240 bp
>AT206678 NZ_CP102592:445785-445919 [Xanthomonas sp. CFBP 8443]
ATGAAGCGTACTTTTGCGTGGATGCTGCTGGCGATGTTCTCGGTCGGCCTGCTGTCTGGCTGCAACACCGTTGCCGGTGC
CGGCAAGGACGTGCAGAGCGCCGGCGAGAAGGTCGAAGACGCCGCCAAGAACTGA
ATGAAGCGTACTTTTGCGTGGATGCTGCTGGCGATGTTCTCGGTCGGCCTGCTGTCTGGCTGCAACACCGTTGCCGGTGC
CGGCAAGGACGTGCAGAGCGCCGGCGAGAAGGTCGAAGACGCCGCCAAGAACTGA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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