Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) relBE/ParE-RelB
Location 5171699..5172221 Replicon chromosome
Accession NZ_CP077083
Organism Pseudomonas salmasensis strain SWRI126

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag HU731_RS23230 Protein ID WP_186605787.1
Coordinates 5171699..5171992 (-) Length 98 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A7Y1LCT8
Locus tag HU731_RS23235 Protein ID WP_020301039.1
Coordinates 5171982..5172221 (-) Length 80 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HU731_RS23200 (HU731_023200) 5167092..5167652 - 561 WP_003189463.1 glycine cleavage system protein R -
HU731_RS23205 (HU731_023205) 5167915..5168793 + 879 WP_014717368.1 4-hydroxy-tetrahydrodipicolinate synthase -
HU731_RS23210 (HU731_023210) 5168811..5169926 + 1116 WP_186605777.1 outer membrane protein assembly factor BamC -
HU731_RS23215 (HU731_023215) 5169931..5170689 + 759 WP_186605779.1 MBL fold metallo-hydrolase -
HU731_RS23220 (HU731_023220) 5170717..5171430 + 714 WP_027604309.1 phosphoribosylaminoimidazolesuccinocarboxamide synthase -
HU731_RS23230 (HU731_023230) 5171699..5171992 - 294 WP_186605787.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
HU731_RS23235 (HU731_023235) 5171982..5172221 - 240 WP_020301039.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
HU731_RS23240 (HU731_023240) 5172864..5173115 + 252 WP_057701154.1 hypothetical protein -
HU731_RS23245 (HU731_023245) 5173188..5174414 - 1227 WP_056791672.1 MFS transporter -
HU731_RS23250 (HU731_023250) 5174552..5175493 - 942 WP_186605789.1 LysR family transcriptional regulator -
HU731_RS23255 (HU731_023255) 5175650..5176966 + 1317 WP_186605791.1 MFS transporter -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.



Sequences


Toxin        


Download         Length: 98 a.a.        Molecular weight: 11680.51 Da        Isoelectric Point: 10.2570

>T206678 WP_186605787.1 NZ_CP077083:c5171992-5171699 [Pseudomonas salmasensis]
MTYSLDFDARALKEWQKLGDTLRQQLKKKLVEILNNPRIEANRLHRLPDCYKIKLRSSGYRLVYQVIEQEITVFVVAVDK
RERDQAYRKASERLEQR

Download         Length: 294 bp

>T206678 NZ_CP102592:445537-445689 [Xanthomonas sp. CFBP 8443]
ATGAAGCGACTGCTCACCTTGATGATGCTGACCCTGTTCTGTGCGGGCATGCTGACTGGCTGCAACACCATGGCCGGTGC
CGGCAAAGACATGCAGAAGGCGGGCGAGAAGGTGGAAGACAAGGCGGGCGATTGCAGCGACGGCAAGTGCTGA

Antitoxin


Download         Length: 80 a.a.        Molecular weight: 9027.43 Da        Isoelectric Point: 4.6017

>AT206678 WP_020301039.1 NZ_CP077083:c5172221-5171982 [Pseudomonas salmasensis]
MASINIRIDDDLKTRAYLELEKLGVTPSELIRQALQYVAERGQLPFKPVLMTEEDEALMATVRERLASPQRVRVSLDDL

Download         Length: 240 bp

>AT206678 NZ_CP102592:445785-445919 [Xanthomonas sp. CFBP 8443]
ATGAAGCGTACTTTTGCGTGGATGCTGCTGGCGATGTTCTCGGTCGGCCTGCTGTCTGGCTGCAACACCGTTGCCGGTGC
CGGCAAGGACGTGCAGAGCGCCGGCGAGAAGGTCGAAGACGCCGCCAAGAACTGA

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Source ID Structure
AlphaFold DB A0A7Y1LCT8

References