Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) hicAB/HicA(toxin)
Location 944401..945011 Replicon chromosome
Accession NZ_CP077083
Organism Pseudomonas salmasensis strain SWRI126

Toxin (Protein)


Gene name hicA Uniprot ID -
Locus tag HU731_RS03790 Protein ID WP_186608048.1
Coordinates 944401..944652 (+) Length 84 a.a.

Antitoxin (Protein)


Gene name hicB Uniprot ID -
Locus tag HU731_RS03795 Protein ID WP_186608047.1
Coordinates 944649..945011 (+) Length 121 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HU731_RS03790 (HU731_003790) 944401..944652 + 252 WP_186608048.1 type II toxin-antitoxin system HicA family toxin Toxin
HU731_RS03795 (HU731_003795) 944649..945011 + 363 WP_186608047.1 type II toxin-antitoxin system HicB family antitoxin Antitoxin
HU731_RS03800 (HU731_003800) 945251..946255 + 1005 WP_186608046.1 Camphene synthase -
HU731_RS03805 (HU731_003805) 946269..947441 - 1173 WP_186608045.1 MFS transporter -
HU731_RS03810 (HU731_003810) 947574..948161 + 588 WP_186608044.1 TetR/AcrR family transcriptional regulator -
HU731_RS03815 (HU731_003815) 948145..949500 - 1356 WP_186608043.1 MATE family efflux transporter -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

HicA mRNA interferase family

(20-76)

Antitoxin

Uncharacterised protein family HicB

(55-105)


Sequences

Toxin        


Download         Length: 84 a.a.        Molecular weight: 9529.11 Da        Isoelectric Point: 10.0459

>T206672 WP_186608048.1 NZ_CP077083:944401-944652 [Pseudomonas salmasensis]
VSKNEKLLAKLLNEHMAFTWSELVTLFRRLGYTQIEGAGSRVKFDMGDPSAMITLHKPHPGNELKHYIRRQIIEQLKSGE
LIP

Download         Length: 252 bp

>T206672 NZ_CP102580:461666-462055 [Acinetobacter baumannii]
TTGATCAACCATTTGAATTTTAAGCTGAAATATAGTCGTTTTTCGATTATATTTCAGTTTTTTATTGGCTTAAGCTTAGC
AGTTCTATTTTATCAATTAATGCCGTTACTATGGTGGTTAGTTGTAATCAGCTTACTATTTATCAGCTTTATTTTCTTTT
TAAAGCGTCCGCAGCTTGCACAAATTGCTTATTTAGATAAAAAACTATGGTCGCTTGCTTATAAGTCACAGAACACCGTT
TCTCGCGTCAAAATTTTAAAAATAATTGATTGTCAGATTTTCATAGTGATCTATTTTGAAGGTCATAAAACACTAACTTC
TATCATTTGGTTTGATCAAATGTCATTAGCAGAGTGGAAAAAGCTTAAAACTTTAGAAAAACTCTATTAA

Antitoxin


Download         Length: 121 a.a.        Molecular weight: 12986.92 Da        Isoelectric Point: 6.8522

>AT206672 WP_186608047.1 NZ_CP077083:944649-945011 [Pseudomonas salmasensis]
MNNQLKHKGYIGSIEASLEDNCLFGKILFIKALVSYEGKTVAELDAAFKEAVEDYLATCQALGQTPEKPCKGSFNVRVGH
DLHLAAALAATRKKVTLNDLTRQALNEFLLQHGAEGLAAV

Download         Length: 363 bp

>AT206672 NZ_CP102580:461402-461659 [Acinetobacter baumannii]
ATGTCTGAAGAAATGACCTTGGAAGAACGTAAAGTAATCTATCGCGCACGTCGTGGTTTAAAGGAAATTGATGTCTATTT
TGACCCTTATGTGAAAAATTATTATTTAAAGGCAGACCCGGCAGAAAAAGCGTTGTTTGCTGAGTTGGTAGAACAGGAAG
ACCCTGATTTACTAGATTGGTTTATGGAAGTATCAGAACCACCACGTACCGAATTACGTGACTTTATCTATAAATTAAAA
CACTATGTTCATGGTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References