Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mazEF/PRK09812-MazE
Location 698275..698906 Replicon chromosome
Accession NZ_CP077081
Organism Pseudomonas atacamensis strain SWRI76

Toxin (Protein)


Gene name mazF Uniprot ID -
Locus tag KSS92_RS03065 Protein ID WP_217879190.1
Coordinates 698544..698906 (+) Length 121 a.a.

Antitoxin (Protein)


Gene name mazE Uniprot ID -
Locus tag KSS92_RS03060 Protein ID WP_122601441.1
Coordinates 698275..698544 (+) Length 90 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KSS92_RS03025 (KSS92_03025) 693774..694319 - 546 WP_076565270.1 hypothetical protein -
KSS92_RS03030 (KSS92_03030) 694316..694570 - 255 WP_016772026.1 acyl carrier protein -
KSS92_RS03035 (KSS92_03035) 694580..694855 - 276 WP_016772025.1 phosphopantetheine-binding protein -
KSS92_RS03040 (KSS92_03040) 694833..695645 - 813 WP_110602643.1 lysophospholipid acyltransferase family protein -
KSS92_RS03045 (KSS92_03045) 695621..696346 - 726 WP_125925742.1 beta-ketoacyl synthase chain length factor -
KSS92_RS03050 (KSS92_03050) 696703..697473 + 771 WP_217879189.1 ParA family protein -
KSS92_RS03055 (KSS92_03055) 697604..698038 - 435 WP_122611051.1 thioredoxin TrxC -
KSS92_RS03060 (KSS92_03060) 698275..698544 + 270 WP_122601441.1 PbsX family transcriptional regulator Antitoxin
KSS92_RS03065 (KSS92_03065) 698544..698906 + 363 WP_217879190.1 type II toxin-antitoxin system PemK/MazF family toxin Toxin
KSS92_RS03070 (KSS92_03070) 698912..700375 - 1464 WP_217879191.1 YdiU family protein -
KSS92_RS03075 (KSS92_03075) 700424..703777 - 3354 WP_217879192.1 mechanosensitive channel MscK -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(8-115)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 121 a.a.        Molecular weight: 13395.27 Da        Isoelectric Point: 6.4625

>T206655 WP_217879190.1 NZ_CP077081:698544-698906 [Pseudomonas atacamensis]
MVRRQPPQRGDVYWIDPNPVAGREMMNRHRFVVITPREINALGVSMTVPVTSGGNFSRNMGLAVAITDHETNGVAVCNQV
RSFDIEQRVRDGTAKFIERLDDVTMSDIVDRVISAIDPLS

Download         Length: 363 bp

>T206655 NZ_CP102548:c50855-50706 [Klebsiella pneumoniae]
ATGACGAAATATGCCCTTATCGGGTTGCTCGCCGTGTGCGCCACGGTGTTGTGTTTTTCACTGATATTCAGGGAACGGTT
ATGTGAACTGAATATTCACAGGGGAAATACAGTGGTGCAGGTAACTCTGGCCTACGAAGCACGGAAGTAA

Antitoxin


Download         Length: 90 a.a.        Molecular weight: 9549.95 Da        Isoelectric Point: 5.1069

>AT206655 WP_122601441.1 NZ_CP077081:698275-698544 [Pseudomonas atacamensis]
MSVTSRIRRQGGAAVITIPPTLLKLLHLEVGAQLELNVVDGELIARPAVAATRKRYSLSELLEGAEELQKLNAQTSETLE
GDSVGRELG

Download         Length: 270 bp

>AT206655 NZ_CP102548:50899-50960 [Klebsiella pneumoniae]
TTAAGGTACTTCATGCAGACCTCACGAGTTAATGGATTAACGAGTGGGGTCTTCGCATTTCT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References