Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RHH(antitoxin)
Location 2864013..2864560 Replicon chromosome
Accession NZ_CP077077
Organism Pseudomonas maumuensis strain COW77

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag KSS90_RS12890 Protein ID WP_050705773.1
Coordinates 2864285..2864560 (+) Length 92 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag KSS90_RS12885 Protein ID WP_217869702.1
Coordinates 2864013..2864285 (+) Length 91 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KSS90_RS12870 (KSS90_12870) 2859584..2860366 + 783 WP_217869700.1 ATP-binding cassette domain-containing protein -
KSS90_RS12875 (KSS90_12875) 2860363..2861325 + 963 WP_217869701.1 siderophore ABC transporter substrate-binding protein -
KSS90_RS12880 (KSS90_12880) 2861553..2863790 + 2238 WP_225933166.1 TonB-dependent receptor -
KSS90_RS12885 (KSS90_12885) 2864013..2864285 + 273 WP_217869702.1 ribbon-helix-helix domain-containing protein Antitoxin
KSS90_RS12890 (KSS90_12890) 2864285..2864560 + 276 WP_050705773.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
KSS90_RS12895 (KSS90_12895) 2864593..2865489 - 897 WP_217869703.1 LysR substrate-binding domain-containing protein -
KSS90_RS12900 (KSS90_12900) 2865610..2866941 + 1332 WP_217869704.1 serine hydrolase -
KSS90_RS12905 (KSS90_12905) 2866981..2868588 - 1608 WP_217869705.1 methyl-accepting chemotaxis protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-90)

Antitoxin

Ribbon-helix-helix protein, CopG

(10-47)


Sequences

Toxin        


Download         Length: 92 a.a.        Molecular weight: 10660.28 Da        Isoelectric Point: 8.5491

>T206642 WP_050705773.1 NZ_CP077077:2864285-2864560 [Pseudomonas maumuensis]
MDLKWTSKALSDIARLYEFLAAVNKPAAVRTVQQLTGAASMLLANPRIGERLEEFEPRDVRRIQIGHYEMRYEIADSTLF
LLRLWHTREDR

Download         Length: 276 bp

>T206642 NZ_CP102542:c2536190-2535807 [Lacticaseibacillus rhamnosus]
ATGGATGTAACAGTCAAACGCGGGGATGTATTTTTCGCCGATTTATCGCCGGTTGTCGGGTCGGAACAAGGCGGCAACCG
GCCCGTACTTATTATTCAAAACAATGTTGGTAACCATTATAGCCCCACTGTTATCGTGGCTGCCATTACCTCCAAAATCC
AAAAACCCAAAATGCCCACCCATGTCGGTTTGCGCGCCAAGCAAGACGGGGTTGAGCGTAATTCAGTCATTTTGCTTGAA
CAGATTCGTACAATTGATAAGCAACGGTTACAGGCACGCGTTACCGCTCTTTCAAGTGCCAAAATGGCAGCGGTGGATCG
GGCACTGGCGATATCGGTCGGACTCGTCAGCTTGCCTAAGCCGAAAACATATAATAAAAACTAA

Antitoxin


Download         Length: 91 a.a.        Molecular weight: 10126.48 Da        Isoelectric Point: 5.1239

>AT206642 WP_217869702.1 NZ_CP077077:2864013-2864285 [Pseudomonas maumuensis]
MASTVKTRSVTAHVPVQLAEKVDLLAERLERSKNWIVKQALIAWIDQEEERSRLTREALADVDADRVIDHQAVQAWADSL
GTDTPLPVPR

Download         Length: 273 bp

>AT206642 NZ_CP102542:c2536458-2536210 [Lacticaseibacillus rhamnosus]
ATGAAGAAGGAAACGTCAGTAACGGTCGCGCTTGATAGTGCTATCAAAGCGCGTTTGGATGCCTATTGCGAGTTGAATGA
TATGGGTGTTCAGGATGTCATTACTGAAGCAGTGGCGAAGTTTTTGCAGTCACAAGCACCTGAGATCAATCAATTGATTT
CTGGCTATGTGGCAATGGGACAAATCAATACGGAAATCAGCCATGCTTTCTCCGCCTGCGAAAGTGAGGCATACGCCCAT
ATTCGATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References