Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumAB/upstrm_HI1419-DUF971
Location 1588436..1589036 Replicon chromosome
Accession NZ_CP077077
Organism Pseudomonas maumuensis strain COW77

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag KSS90_RS07355 Protein ID WP_217868820.1
Coordinates 1588734..1589036 (-) Length 101 a.a.

Antitoxin (Protein)


Gene name PumB Uniprot ID -
Locus tag KSS90_RS07350 Protein ID WP_217868819.1
Coordinates 1588436..1588741 (-) Length 102 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KSS90_RS07340 (KSS90_07340) 1586834..1587289 + 456 WP_217868817.1 hypothetical protein -
KSS90_RS07345 (KSS90_07345) 1587445..1588371 + 927 WP_217868818.1 DMT family transporter -
KSS90_RS07350 (KSS90_07350) 1588436..1588741 - 306 WP_217868819.1 putative addiction module antidote protein Antitoxin
KSS90_RS07355 (KSS90_07355) 1588734..1589036 - 303 WP_217868820.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
KSS90_RS07360 (KSS90_07360) 1589113..1590276 - 1164 WP_217868822.1 MFS transporter -
KSS90_RS07365 (KSS90_07365) 1590383..1591276 + 894 WP_217868823.1 LysR family transcriptional regulator -
KSS90_RS25665 1591401..1591529 + 129 WP_256206021.1 PA1414 family protein -
KSS90_RS07370 (KSS90_07370) 1591652..1593031 - 1380 WP_217868824.1 sodium:solute symporter -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(4-94)

Antitoxin

Uncharacterized protein HI1420

(6-94)


Sequences

Toxin        


Download         Length: 101 a.a.        Molecular weight: 11341.97 Da        Isoelectric Point: 10.4297

>T206641 WP_217868820.1 NZ_CP077077:c1589036-1588734 [Pseudomonas maumuensis]
MKTIESSSFRHWLIGLRDATARARIVARVNRLKEGLAGDVSPVGHGMSELRVHYGPGYRVYFHQYGDTLIVLLCGGDKSS
QQRDIKAARQILQSWRMQND

Download         Length: 303 bp

>T206641 NZ_CP102542:c2439246-2438899 [Lacticaseibacillus rhamnosus]
ATGACATATAAGGCTAAGCAAGGTGATGTGGTGTGGCTTGATTTTGATCCGTCCGAGGGTCATGAAATTAGAAAAAGATG
CCCAGCTGTTGTTTTAAGCAGTAACGCATACAATCGTGCAACCGGATTTGTGATTGTCGCACCAATTACCTCAACAATTC
GGACACTACCTGGTTATGTTGATATTGTATCCAATAAAATTCGTGGTCAGGTTGTCACTTCGCAGGTTTATTCTCTGGAT
GTCACTGAACAAGGCAACCGAAAAATCGATTTTATTGAAAGAATGAACATTGAAGATTTTTATACAGTCGCTCAATTCAC
CAAAATGAATTTTGATTTTAAATTTTAG

Antitoxin


Download         Length: 102 a.a.        Molecular weight: 10869.29 Da        Isoelectric Point: 5.5900

>AT206641 WP_217868819.1 NZ_CP077077:c1588741-1588436 [Pseudomonas maumuensis]
MTETFHEFDAAAYLTSPETIAQFMTDALETGDAAYVAKAVGVVARARGMSELAKETGLSREQLYRSFSEHGNPTLKSFLT
VMKALGIDMAARPHLSQQGAG

Download         Length: 306 bp

>AT206641 NZ_CP102542:c2439464-2439246 [Lacticaseibacillus rhamnosus]
ATGATGGATGTGAAAGTTGTAAAACGTGGAAACTCGTTAGCTTTATCACTTCCGAGCAGTGCGGGTTTCAAACGAGGCGA
GGCGTTTTTGCTGATTTCAGATGAAAAAGGTGGTTATCTGTTGATCCCAAAGGTAAAAAATCCCTATACCAAAGCAAAAC
CATTATCATTCCATCAAGAAGAAGCTTGGCCGGATTTTGACTATGAGGATATTGAATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References