Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RHH(antitoxin)
Location 2210172..2210719 Replicon chromosome
Accession NZ_CP077076
Organism Pseudomonas fakonensis strain COW40

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag KSS94_RS09985 Protein ID WP_217842815.1
Coordinates 2210172..2210447 (-) Length 92 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag KSS94_RS09990 Protein ID WP_217842816.1
Coordinates 2210447..2210719 (-) Length 91 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KSS94_RS09965 (KSS94_09965) 2205318..2206904 - 1587 WP_217842811.1 rhodanese-related sulfurtransferase -
KSS94_RS09970 (KSS94_09970) 2206901..2207503 - 603 WP_217842812.1 cysteine dioxygenase -
KSS94_RS09975 (KSS94_09975) 2207781..2208716 + 936 WP_217842813.1 ABC transporter substrate-binding protein -
KSS94_RS09980 (KSS94_09980) 2208762..2210081 + 1320 WP_217842814.1 LLM class flavin-dependent oxidoreductase -
KSS94_RS09985 (KSS94_09985) 2210172..2210447 - 276 WP_217842815.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
KSS94_RS09990 (KSS94_09990) 2210447..2210719 - 273 WP_217842816.1 ribbon-helix-helix domain-containing protein Antitoxin
KSS94_RS09995 (KSS94_09995) 2211024..2212664 - 1641 WP_225935857.1 methyl-accepting chemotaxis protein -
KSS94_RS10000 (KSS94_10000) 2212926..2214173 + 1248 WP_217838745.1 IS256 family transposase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 2192298..2225829 33531
- flank IS/Tn - - 2212926..2214173 1247


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-90)

Antitoxin

Ribbon-helix-helix protein, CopG

(10-47)


Sequences

Toxin        


Download         Length: 92 a.a.        Molecular weight: 10615.25 Da        Isoelectric Point: 8.0601

>T206638 WP_217842815.1 NZ_CP077076:c2210447-2210172 [Pseudomonas fakonensis]
MELKWTSKGLSDLARLHEFLAAVNPSAAARTVQQLAAAPNVLLTNPRVGERLEEFEPREVRRILVGHYEMRYEITPSCIY
LLRLWHTREER

Download         Length: 276 bp

>T206638 NZ_CP102541:1652778-1653101 [Bifidobacterium longum subsp. infantis]
ATGAAACGAGGTGAGATTTGGACGTTGCAGGCCGATGGCTACGCCAGCAAGCCACGGCCGGTTGTCATCGTGCAGAGCGA
TGCCGTCGATCGGTTCGATTCCGTCATCACTTGTCTGCTGACCTCATACGATTCCTCCGACATCGACACGCGGGTCCGAT
TGGAACCAAGTCCGGAGAACGGCCTGAACAAAGTGAGTTACGTGATGACGGACAAGATCGTCACCGTCGACCGCAAACTG
CTGGGATACCAAGTCGGCGTGGTTGATGATGCAGCCATGGCGAATATCGGCCGTCAGCTCATGCGGGTTCTAGGTTTGCT
GTGA

Antitoxin


Download         Length: 91 a.a.        Molecular weight: 10057.33 Da        Isoelectric Point: 4.8308

>AT206638 WP_217842816.1 NZ_CP077076:c2210719-2210447 [Pseudomonas fakonensis]
MTIAAKTRSVTAHVPVELAERIDEIATRLERSKNWIVKQALSDWLAQEDERNRLTLEALADVDAGRVIDHQSVQAWAESL
GTDSPLPVPR

Download         Length: 273 bp

>AT206638 NZ_CP102541:1652546-1652791 [Bifidobacterium longum subsp. infantis]
ATGAGCATGCAGATTGCCACGCGAGTTGATGACGAGCAGGCTGCGTTGTTTAAGGAGACGACCCGACAGCTGGGCATCAC
CCCGGCCGATGCCCTGCGTATGTTCATCAGCGCGTTCAATGATTACCGTGGGTTCCCCTATGAGGTGCGTTTGCCACGAA
ATGACGTGGAGCCGTTTGCGTCCGAGCGGGACGCTACTGAGTATGCCAGTCGTCTCGCCTTGAGGATGTCCGATGAAACG
AGGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References