Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RHH(antitoxin)
Location 4543522..4544069 Replicon chromosome
Accession NZ_CP077075
Organism Pseudomonas xanthosomae strain COR54

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag KSS93_RS19995 Protein ID WP_217885653.1
Coordinates 4543794..4544069 (+) Length 92 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag KSS93_RS19990 Protein ID WP_217885652.1
Coordinates 4543522..4543794 (+) Length 91 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KSS93_RS19980 (KSS93_19980) 4538849..4541260 + 2412 WP_217885651.1 TonB-dependent receptor -
KSS93_RS19985 (KSS93_19985) 4541578..4543218 + 1641 WP_225917223.1 methyl-accepting chemotaxis protein -
KSS93_RS19990 (KSS93_19990) 4543522..4543794 + 273 WP_217885652.1 ribbon-helix-helix domain-containing protein Antitoxin
KSS93_RS19995 (KSS93_19995) 4543794..4544069 + 276 WP_217885653.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
KSS93_RS20000 (KSS93_20000) 4544155..4545474 - 1320 WP_217885654.1 LLM class flavin-dependent oxidoreductase -
KSS93_RS20005 (KSS93_20005) 4545606..4546559 - 954 WP_217885655.1 ABC transporter substrate-binding protein -
KSS93_RS20010 (KSS93_20010) 4546836..4547438 + 603 WP_217885656.1 cysteine dioxygenase -
KSS93_RS20015 (KSS93_20015) 4547435..4549021 + 1587 WP_217885657.1 rhodanese-related sulfurtransferase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-90)

Antitoxin

Ribbon-helix-helix protein, CopG

(10-47)


Sequences

Toxin        


Download         Length: 92 a.a.        Molecular weight: 10645.27 Da        Isoelectric Point: 8.0601

>T206635 WP_217885653.1 NZ_CP077075:4543794-4544069 [Pseudomonas xanthosomae]
MELKWTSKGLSDLARLHEFLAAVNPSAAVRTVQQLVAAPNVLLTNPRVGERLEEFEPREVRRSLVGHYEMRYEITPSCIY
LLRLWHTREER

Download         Length: 276 bp

>T206635 NZ_CP102541:c1045820-1045518 [Bifidobacterium longum subsp. infantis]
ATCAAGCAATCCGCCGAATACCGCAAATGGTTCAAGAAACTCAGGGACCACAAAGCGAAGGCCGCCATCCAAGCCCGGCT
CGATGCCTGCAAGCTCGCAGGCAGGCCATTCGGCGACATCAAACCCGTGGGAGGCCCGGTCAGCGAGATGCGGTTCCACA
CCGGGGCCGGATACCGCGTCTACTTCGCCATGCAGGGCAACGTGCTCATGCTGCTGCTCGCAGGCGGCGACAAAAGCACC
CAGCAGACCGACATCAGACAAGCCCACGACATCCTCAACGACTACAAGGAACAACGACAATGA

Antitoxin


Download         Length: 91 a.a.        Molecular weight: 10100.36 Da        Isoelectric Point: 5.1358

>AT206635 WP_217885652.1 NZ_CP077075:4543522-4543794 [Pseudomonas xanthosomae]
MTIAAKTRSVTAHVPVELAERIDEIATRLERSKNWIVKQALSDWLAQEDERNRLTREALADVDAGRVIDHQSVQAWAESL
GTDSPLPVPR

Download         Length: 273 bp

>AT206635 NZ_CP102541:c1045521-1045237 [Bifidobacterium longum subsp. infantis]
ATGAGCACCGAATTCACCGACTACGACACCAGCGAATACCTCGAAAACGAACAGGACATCATCGCCTACCTCAACGCCAT
AGCCGAATATGACGACCCCGCACTCATGCAGGCCGCGCTCGGCAACGTCGCCAAGGCCCGGGGCATGACCCAGATCGCCA
AGGACGCGGGCGTGGGGCGCGAAAGCCTCTACAAGAGCCTCAGCAAGGACGGCAACCCCAGCTTCCAGACCATCGCCAAG
GTAATCCACGCCCTCGGCGGACGCCTCACCATCCAAGCCGCCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References