Detailed information of TA system TA206624

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/ParE-YafN
• Location: 381787..382303
• Replicon: chromosome
• Accession: NZ_CP077074
• Organism: Pseudomonas sessilinigenes strain CMR12a

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: KSS89_RS01730
• Protein ID: WP_124345436.1
• Coordinates: 382022..382303 (+)
• Length: 94 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: KSS89_RS01725
• Protein ID: WP_085598199.1
• Coordinates: 381787..382032 (+)
• Length: 82 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
KSS89_RS01705 (KSS89_01705)	376788..379004	-	2217	WP_124345433.1	outer membrane assembly lipoprotein YfiO	-
KSS89_RS01710 (KSS89_01710)	379269..380852	+	1584	WP_124345434.1	glycosyltransferase family 39 protein	-
KSS89_RS01715 (KSS89_01715)	381001..381462	+	462	WP_068576252.1	YbaK/EbsC family protein	-
KSS89_RS01720 (KSS89_01720)	381477..381725	+	249	WP_124345435.1	DUF2789 domain-containing protein	-
KSS89_RS01725 (KSS89_01725)	381787..382032	+	246	WP_085598199.1	type II toxin-antitoxin system prevent-host-death family antitoxin	Antitoxin
KSS89_RS01730 (KSS89_01730)	382022..382303	+	282	WP_124345436.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
KSS89_RS01735 (KSS89_01735)	382435..382863	+	429	WP_068576245.1	winged helix DNA-binding protein	-
KSS89_RS01740 (KSS89_01740)	382860..384947	+	2088	WP_124345437.1	FUSC family protein	-
KSS89_RS01745 (KSS89_01745)	384944..385153	+	210	WP_022643266.1	DUF1656 domain-containing protein	-
KSS89_RS01750 (KSS89_01750)	385150..386040	+	891	WP_068576241.1	HlyD family secretion protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (5-83)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (8-71)

Sequences

Toxin

Protein

• Length: 94 a.a.
• Molecular weight: 10807.85 Da
• Isoelectric Point: 10.6758

>T206624 WP_124345436.1 NZ_CP077074:382022-382303 [Pseudomonas sessilinigenes]
MTYKLEFLPSALKEWNKLGHTLREQFKKKLAQRLQMPQVPADALYGLPDCYKIKLKASGYRLVYKVIEQRVVVAVVAVGK
RERGAVYEQARKR

Nucleotide

• Length: 282 bp

>T206624 NZ_CP102530:c463130-462762 [Lacticaseibacillus paracasei subsp. paracasei]
ATGTATAAAATTGACTTCTATGAGGATCGCGATGGCTACTCTGAGATCGAAGACTTTCTTGATCAGTTACGCCATAGTCA
TCAAAAAAATAATGTGAGCCTTTTAAACAAAATCACAAAGGAACTCTACATGCTGCAAAATCTTGGTCCGCGCTTACGTG
AACCTCACGCGAAGTTTCTGAAGGGATATGCTTATCCGATCATGGAATTGCGTCCCATGCAAGAAAGAATCTTTTATGCT
GCATGGCAAAAGGATCATTTCGTTTTGCTTCATCACTACACCAAGAAAACAAACAAAACTGATCACAGAGAAATTTTACG
GGCACAGTCTAACCTCGAAGATTGGCTCTCTAGAAAGGAAGAAAATTGA

Antitoxin

Protein

• Length: 82 a.a.
• Molecular weight: 8759.08 Da
• Isoelectric Point: 4.3455

>AT206624 WP_085598199.1 NZ_CP077074:381787-382032 [Pseudomonas sessilinigenes]
MQSILADKAVSVSELKKNPSAVLNGAQGGPVAVLNHNRVMGYMIPAEVFEALMERLDDLELAEIVRARSQETPVPVSLDD
L

Nucleotide

• Length: 246 bp

>AT206624 NZ_CP102530:c462762-462502 [Lacticaseibacillus paracasei subsp. paracasei]
ATGACGACATGGGAAGACTTCAGTCAGAAACTGAAGAAGGACAATCCAGAAAAGTTGGCAATCATCAAAACCTTGGCCGA
TTTAGAAAGTGAACGAATCAAGCAAGGAATCTCTCAAAAGGACTTTGCAGAAAAAATTGGTATGAAACAGCCGCAACTAG
CAAAGATTGAGCGCTTAGACTCTCTTCCGACTCTGGCAACACTCAATCGATACGCGAGAGGGCTTGGAAAAGAAATTCGT
TTATCAATTGTTACTCAGTGA