Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 381787..382303 Replicon chromosome
Accession NZ_CP077074
Organism Pseudomonas sessilinigenes strain CMR12a

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag KSS89_RS01730 Protein ID WP_124345436.1
Coordinates 382022..382303 (+) Length 94 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag KSS89_RS01725 Protein ID WP_085598199.1
Coordinates 381787..382032 (+) Length 82 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KSS89_RS01705 (KSS89_01705) 376788..379004 - 2217 WP_124345433.1 outer membrane assembly lipoprotein YfiO -
KSS89_RS01710 (KSS89_01710) 379269..380852 + 1584 WP_124345434.1 glycosyltransferase family 39 protein -
KSS89_RS01715 (KSS89_01715) 381001..381462 + 462 WP_068576252.1 YbaK/EbsC family protein -
KSS89_RS01720 (KSS89_01720) 381477..381725 + 249 WP_124345435.1 DUF2789 domain-containing protein -
KSS89_RS01725 (KSS89_01725) 381787..382032 + 246 WP_085598199.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
KSS89_RS01730 (KSS89_01730) 382022..382303 + 282 WP_124345436.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
KSS89_RS01735 (KSS89_01735) 382435..382863 + 429 WP_068576245.1 winged helix DNA-binding protein -
KSS89_RS01740 (KSS89_01740) 382860..384947 + 2088 WP_124345437.1 FUSC family protein -
KSS89_RS01745 (KSS89_01745) 384944..385153 + 210 WP_022643266.1 DUF1656 domain-containing protein -
KSS89_RS01750 (KSS89_01750) 385150..386040 + 891 WP_068576241.1 HlyD family secretion protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-83)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(8-71)


Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 10807.85 Da        Isoelectric Point: 10.6758

>T206624 WP_124345436.1 NZ_CP077074:382022-382303 [Pseudomonas sessilinigenes]
MTYKLEFLPSALKEWNKLGHTLREQFKKKLAQRLQMPQVPADALYGLPDCYKIKLKASGYRLVYKVIEQRVVVAVVAVGK
RERGAVYEQARKR

Download         Length: 282 bp

>T206624 NZ_CP102530:c463130-462762 [Lacticaseibacillus paracasei subsp. paracasei]
ATGTATAAAATTGACTTCTATGAGGATCGCGATGGCTACTCTGAGATCGAAGACTTTCTTGATCAGTTACGCCATAGTCA
TCAAAAAAATAATGTGAGCCTTTTAAACAAAATCACAAAGGAACTCTACATGCTGCAAAATCTTGGTCCGCGCTTACGTG
AACCTCACGCGAAGTTTCTGAAGGGATATGCTTATCCGATCATGGAATTGCGTCCCATGCAAGAAAGAATCTTTTATGCT
GCATGGCAAAAGGATCATTTCGTTTTGCTTCATCACTACACCAAGAAAACAAACAAAACTGATCACAGAGAAATTTTACG
GGCACAGTCTAACCTCGAAGATTGGCTCTCTAGAAAGGAAGAAAATTGA

Antitoxin


Download         Length: 82 a.a.        Molecular weight: 8759.08 Da        Isoelectric Point: 4.3455

>AT206624 WP_085598199.1 NZ_CP077074:381787-382032 [Pseudomonas sessilinigenes]
MQSILADKAVSVSELKKNPSAVLNGAQGGPVAVLNHNRVMGYMIPAEVFEALMERLDDLELAEIVRARSQETPVPVSLDD
L

Download         Length: 246 bp

>AT206624 NZ_CP102530:c462762-462502 [Lacticaseibacillus paracasei subsp. paracasei]
ATGACGACATGGGAAGACTTCAGTCAGAAACTGAAGAAGGACAATCCAGAAAAGTTGGCAATCATCAAAACCTTGGCCGA
TTTAGAAAGTGAACGAATCAAGCAAGGAATCTCTCAAAAGGACTTTGCAGAAAAAATTGGTATGAAACAGCCGCAACTAG
CAAAGATTGAGCGCTTAGACTCTCTTCCGACTCTGGCAACACTCAATCGATACGCGAGAGGGCTTGGAAAAGAAATTCGT
TTATCAATTGTTACTCAGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References