Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) ataRT/DUF1778(antitoxin)
Location 336326..337179 Replicon plasmid unnamed1
Accession NZ_CP076854
Organism Rhizobium sp. WYJ-E13

Toxin (Protein)


Gene name ataT Uniprot ID -
Locus tag KQ933_RS23125 Protein ID WP_216760166.1
Coordinates 336326..336856 (-) Length 177 a.a.

Antitoxin (Protein)


Gene name ataR Uniprot ID -
Locus tag KQ933_RS23130 Protein ID WP_216760167.1
Coordinates 336844..337179 (-) Length 112 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KQ933_RS23110 (KQ933_23110) 331901..332830 + 930 WP_216760164.1 substrate-binding domain-containing protein -
KQ933_RS23115 (KQ933_23115) 332845..334989 + 2145 WP_216760165.1 methyl-accepting chemotaxis protein -
KQ933_RS23120 (KQ933_23120) 335088..336106 - 1019 Protein_322 beta-lactamase family protein -
KQ933_RS33545 336107..336238 + 132 Protein_323 LuxR C-terminal-related transcriptional regulator -
KQ933_RS23125 (KQ933_23125) 336326..336856 - 531 WP_216760166.1 GNAT family N-acetyltransferase Toxin
KQ933_RS23130 (KQ933_23130) 336844..337179 - 336 WP_216760167.1 DUF1778 domain-containing protein Antitoxin
KQ933_RS33550 337274..337558 + 285 WP_253958401.1 hypothetical protein -
KQ933_RS33555 337557..337700 + 144 Protein_327 helix-turn-helix domain-containing protein -
KQ933_RS23145 (KQ933_23145) 337925..339133 - 1209 WP_216760169.1 MFS transporter -
KQ933_RS23150 (KQ933_23150) 339193..340173 - 981 WP_216760170.1 AraC family transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - gmd / htpB / gmd 1..2149667 2149667


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(50-151)

Antitoxin

Vibrio phage ICP1, Orf50

(30-105)


Sequences

Toxin        


Download         Length: 177 a.a.        Molecular weight: 18953.63 Da        Isoelectric Point: 5.7067

>T206572 WP_216760166.1 NZ_CP076854:c336856-336326 [Rhizobium sp. WYJ-E13]
MAEIDDAPDQPAPRLSAPVALTVDHDVSGFDCGEPVLNDWLRHRALKNESRFSRTYVVCEGNRVVGYFCISAGSVERGIA
PGKVRCNAPDVIPVSVIGRLAVSRDHAGKGLGADLLSDALRRIALVSQSIGIGAVLVQAKDDAAKRFYLRCAEFIEYPED
SRTLFLPIETVVAGFG

Download         Length: 531 bp

>T206572 NZ_CP102488:3938080-3938265 [Escherichia coli O15:H18]
GTGAAAAGTGCAGACGTGATCGCCATCCTGAAGCAGCATGGCTGGGAACATATTCGAACCCGTGGCAGTCATCATCAGTT
CCGCCACCCTGTTCATCCGGGTCTGGTGACGGTTCCGCACCCTAAAAAAGATATTAAGCCCGGTACGCTGGCGCAAATTG
GGCGTCAGGCTGGTTTAACATTTTAA

Antitoxin


Download         Length: 112 a.a.        Molecular weight: 12057.77 Da        Isoelectric Point: 11.0226

>AT206572 WP_216760167.1 NZ_CP076854:c337179-336844 [Rhizobium sp. WYJ-E13]
MTKTRTAPSASSPSAAVSARASAADTKGSINLRIETGTRQLIDNAAAVLGKTRTEFMVESARRQAVDVLLDQRLFTLDPE
RYDAFIHALDNPPAPGPKLKALLRRTPAWQK

Download         Length: 336 bp

>AT206572 NZ_CP102488:3938282-3938692 [Escherichia coli O15:H18]
ATGTTTTATCCCGCCTATATCCACAGTGATCCTGACGGCAGCGCCAGCGGTTTTTTCCCTGATGTTCCAGGCTGTTATTT
TGCTGGTGATACGCTGGACAACGCTTTCCAGGATGCGCGAAGTGCACTGGTCGCGCACTTCGAAACCTTATGCGAGATGA
ATGAAGAGTTGCCGCTTCCAGGCTCTGTGGAAACACATCTGGTCCAGCGTGCGCAGGACTTTATTGGCGGGCAATGGTTG
CTGGTGGATATCAATATGAATCAGTTCGAAGGTCGGGCTGAACGTATCAATATTACGATGCCGAAAAGGTTACTGAACAA
GATTGATACCTACGTGCGCAATAACCCAGACTACGCCAACAGAAGTGCGTTTCTGGCAGAAGCTGCCCGGCGTGTATTGC
CGGGCGTTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References