Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | relE-dinJ/YafQ-RelB |
| Location | 2185794..2186400 | Replicon | chromosome |
| Accession | NZ_CP076853 | ||
| Organism | Rhizobium sp. WYJ-E13 | ||
Toxin (Protein)
| Gene name | relE | Uniprot ID | - |
| Locus tag | KQ933_RS11070 | Protein ID | WP_216754932.1 |
| Coordinates | 2185794..2186129 (-) | Length | 112 a.a. |
Antitoxin (Protein)
| Gene name | dinJ | Uniprot ID | - |
| Locus tag | KQ933_RS11075 | Protein ID | WP_216754933.1 |
| Coordinates | 2186119..2186400 (-) | Length | 94 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| KQ933_RS11025 (KQ933_11025) | 2180919..2181518 | + | 600 | WP_253958222.1 | NAD(P)-binding domain-containing protein | - |
| KQ933_RS11030 (KQ933_11030) | 2181530..2181913 | + | 384 | WP_216754925.1 | limonene-1,2-epoxide hydrolase family protein | - |
| KQ933_RS11035 (KQ933_11035) | 2181951..2182574 | - | 624 | WP_216754926.1 | LysE family translocator | - |
| KQ933_RS11040 (KQ933_11040) | 2182797..2183126 | + | 330 | WP_216754927.1 | hypothetical protein | - |
| KQ933_RS11045 (KQ933_11045) | 2183198..2183338 | + | 141 | WP_216754928.1 | hypothetical protein | - |
| KQ933_RS11050 (KQ933_11050) | 2183405..2183587 | + | 183 | WP_216754929.1 | hypothetical protein | - |
| KQ933_RS11055 (KQ933_11055) | 2183694..2183939 | + | 246 | WP_183736155.1 | hypothetical protein | - |
| KQ933_RS11060 (KQ933_11060) | 2183995..2184894 | + | 900 | WP_216754930.1 | transglutaminase family protein | - |
| KQ933_RS11065 (KQ933_11065) | 2184962..2185771 | + | 810 | WP_216754931.1 | transglutaminase family protein | - |
| KQ933_RS11070 (KQ933_11070) | 2185794..2186129 | - | 336 | WP_216754932.1 | type II toxin-antitoxin system YafQ family toxin | Toxin |
| KQ933_RS11075 (KQ933_11075) | 2186119..2186400 | - | 282 | WP_216754933.1 | type II toxin-antitoxin system RelB/DinJ family antitoxin | Antitoxin |
| KQ933_RS33420 | 2186484..2186678 | - | 195 | WP_253958223.1 | type II toxin-antitoxin system HicA family toxin | - |
| KQ933_RS11080 (KQ933_11080) | 2186683..2186925 | - | 243 | WP_216754934.1 | DUF1902 domain-containing protein | - |
| KQ933_RS11085 (KQ933_11085) | 2187225..2187857 | - | 633 | WP_216754935.1 | CatB-related O-acetyltransferase | - |
| KQ933_RS11090 (KQ933_11090) | 2188242..2188775 | + | 534 | WP_216754936.1 | DUF1269 domain-containing protein | - |
| KQ933_RS11095 (KQ933_11095) | 2189052..2189690 | - | 639 | WP_216754937.1 | helix-turn-helix transcriptional regulator | - |
| KQ933_RS11100 (KQ933_11100) | 2190166..2190378 | + | 213 | WP_183803919.1 | hypothetical protein | - |
| KQ933_RS11105 (KQ933_11105) | 2190503..2190904 | + | 402 | WP_216754938.1 | helix-turn-helix domain-containing protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 112 a.a. Molecular weight: 12544.19 Da Isoelectric Point: 7.4222
>T206570 WP_216754932.1 NZ_CP076853:c2186129-2185794 [Rhizobium sp. WYJ-E13]
MPSDRNRAKPASTKRASLPRQSSHTKQFQKDWERLSGAGRYDMVALKKVVGLIVDNEGPLPAELKDHELTGDWKDHRECH
IGGDFLLIYSIDDKRNLVVFVSAGTHAELFE
MPSDRNRAKPASTKRASLPRQSSHTKQFQKDWERLSGAGRYDMVALKKVVGLIVDNEGPLPAELKDHELTGDWKDHRECH
IGGDFLLIYSIDDKRNLVVFVSAGTHAELFE
Download Length: 336 bp
>T206570 NZ_CP102488:c3273388-3273215 [Escherichia coli O15:H18]
ATGGCACTATTCTCTAAAATATTAATTTTTTATGTGATTGGTGTGAACATATCCTTTGTCATTATCTGGTTTATCTCACA
TGAGAAAACACATATTCGTTTACTTAGTGCATTCCTGGTAGGAATAACCTGGCCAATGAGTCTGCCTGTGGCATTACTTT
TTTCTCTCTTTTAG
ATGGCACTATTCTCTAAAATATTAATTTTTTATGTGATTGGTGTGAACATATCCTTTGTCATTATCTGGTTTATCTCACA
TGAGAAAACACATATTCGTTTACTTAGTGCATTCCTGGTAGGAATAACCTGGCCAATGAGTCTGCCTGTGGCATTACTTT
TTTCTCTCTTTTAG
Antitoxin
Download Length: 94 a.a. Molecular weight: 10099.60 Da Isoelectric Point: 7.2042
>AT206570 WP_216754933.1 NZ_CP076853:c2186400-2186119 [Rhizobium sp. WYJ-E13]
MAANAYVRARIDSSVKDDAALVLDSLGLTTSDIIRIVLTRIARDKALPVELTRPNARTIAAMEEARAIKADHGKHFDTAE
ELIKSLEGNTLAK
MAANAYVRARIDSSVKDDAALVLDSLGLTTSDIIRIVLTRIARDKALPVELTRPNARTIAAMEEARAIKADHGKHFDTAE
ELIKSLEGNTLAK
Download Length: 282 bp
>AT206570 NZ_CP102488:c3273712-3273416 [Escherichia coli O15:H18]
ATGGAAGGTAAAAACAAGTTCAATACTTATGTTGTTTCTTTTGATTATCCATCATCTTATTCCTCAGTGTTCTTAAGGTT
AAGATCATTGATGTATGATATGAATTTCTCCTCTATCGTGGCTGATGAATATGGGATACCACGACAATTGAATGAAAATT
CCTTCGCAATAACGACATCGTTAGCCGCAAGTGAAATCGAAGATTTAATCAGGCTTAAATGCTTAGACTTACCGGATATT
GATTTTGACCTCAACATTATGACCGTTGATGACTATTTCCGTCAGTTTTACAAGTAG
ATGGAAGGTAAAAACAAGTTCAATACTTATGTTGTTTCTTTTGATTATCCATCATCTTATTCCTCAGTGTTCTTAAGGTT
AAGATCATTGATGTATGATATGAATTTCTCCTCTATCGTGGCTGATGAATATGGGATACCACGACAATTGAATGAAAATT
CCTTCGCAATAACGACATCGTTAGCCGCAAGTGAAATCGAAGATTTAATCAGGCTTAAATGCTTAGACTTACCGGATATT
GATTTTGACCTCAACATTATGACCGTTGATGACTATTTCCGTCAGTTTTACAAGTAG
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
Structures
Toxin
| Source | ID | Structure |
|---|
Antitoxin
| Source | ID | Structure |
|---|