Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relB-parE/ParE-RHH
Location 2064283..2064839 Replicon chromosome
Accession NZ_CP076853
Organism Rhizobium sp. WYJ-E13

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag KQ933_RS10370 Protein ID WP_216758688.1
Coordinates 2064549..2064839 (+) Length 97 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag KQ933_RS10365 Protein ID WP_216758687.1
Coordinates 2064283..2064561 (+) Length 93 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KQ933_RS33400 2059887..2061233 - 1347 WP_253958314.1 hypothetical protein -
KQ933_RS10350 (KQ933_10350) 2061426..2061989 + 564 WP_216758684.1 transglutaminase-like cysteine peptidase -
KQ933_RS10355 (KQ933_10355) 2062194..2063543 + 1350 WP_216758685.1 prolyl oligopeptidase family serine peptidase -
KQ933_RS10360 (KQ933_10360) 2063651..2064100 + 450 WP_216758686.1 DUF3597 domain-containing protein -
KQ933_RS10365 (KQ933_10365) 2064283..2064561 + 279 WP_216758687.1 CopG family ribbon-helix-helix protein Antitoxin
KQ933_RS10370 (KQ933_10370) 2064549..2064839 + 291 WP_216758688.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
KQ933_RS10375 (KQ933_10375) 2064887..2065183 - 297 WP_216758689.1 YkgJ family cysteine cluster protein -
KQ933_RS10380 (KQ933_10380) 2065465..2066946 + 1482 WP_216758690.1 ATPase domain-containing protein -
KQ933_RS10385 (KQ933_10385) 2066960..2069017 + 2058 WP_216758691.1 hybrid sensor histidine kinase/response regulator -
KQ933_RS10390 (KQ933_10390) 2069268..2069531 + 264 WP_216758692.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-94)

Antitoxin

Ribbon-helix-helix protein, CopG

(5-42)


Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 11049.76 Da        Isoelectric Point: 9.0234

>T206568 WP_216758688.1 NZ_CP076853:2064549-2064839 [Rhizobium sp. WYJ-E13]
MPQVVFSPAAIRDLQRLRDLLTPKNPSAARRAGETILAGVRTLCLHPHMGRLIEDLPEQYREWLIDFGDSGYVARYRFDQ
NTVTILAVRHQKEAMF

Download         Length: 291 bp

>T206568 NZ_CP102488:3151234-3151611 [Escherichia coli O15:H18]
ATGAAAACATTACCTGTATTACCCGGGCAGGCGGCCAGTTCGCGTCCGTCTCCTGTTGAAATCTGGCAGACACTGCTGTC
CCGCCTGCTGGACCAGCATTACGGCCTTACGCTGAATGACACACCGTTCTCCGATGAACGTGTGATTGAGCAGCATATTG
AGGCAGGCATTTCACTGTGTGACGCGGTGAACTTTCTCGTTGAAAAATACGCGCTGGTGCGTACCGACCAGCCGGGATTC
AGCGCAGGAGCCCCGTCGCAGTTAATCAACAGCATTGATATTCTCCGGGCTCGCAGGGCGACCGGCCTGATGACCCGGAA
CAATTACAGAATGGTAAATAACATTACCCAGGGCAAGCATCCGGAGGCAAAACGATGA

Antitoxin


Download         Length: 93 a.a.        Molecular weight: 10672.89 Da        Isoelectric Point: 4.9192

>AT206568 WP_216758687.1 NZ_CP076853:2064283-2064561 [Rhizobium sp. WYJ-E13]
MASPTSLKLDDELKGRVQHLAELRRRSSHWIMREAIAQYVAREEKREALRQQTLDAWDEFQATGLHVTGDEVETWLSTWG
TDDELPAPECHK

Download         Length: 279 bp

>AT206568 NZ_CP102488:3150776-3151144 [Escherichia coli O15:H18]
GTGTCAGACACGCACCATGAGACAAATTATCCCGACGACTATAACAACCGCCCCTGGTGGGGGCTGCCCTGCACCATAAC
ACCCTGTTTTGGCGCCCGTCTGGTGCAGGAGGGTAACCGGTTGTATTACCTTGCCGACCGCGCCGGTATCAGAGGCCGGT
TCAGCGACGCGGATGCGTACCATCTGGACCAGGCCTTTCCGCTGCTGATGAAACAACTGGAACTCATACTCACCAGCGGT
GAACTGAATCCCCGCCATCAGCATACCGTCACGCTGTATGCCAGAGGACTGACCTGCGAAGCCGACACCCTCGGCTCCTG
TGGTTACGTTTATATGGCTGTTTATCCGACGCCCGAAACGAAAAAGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References