Detailed information of TA system TA206567

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): parDE/ParE-CC2985
• Location: 781299..781834
• Replicon: chromosome
• Accession: NZ_CP076853
• Organism: Rhizobium sp. WYJ-E13

Toxin (Protein)

• Gene name: parE
• Uniprot ID: -
• Locus tag: KQ933_RS03900
• Protein ID: WP_216757479.1
• Coordinates: 781299..781589 (-)
• Length: 97 a.a.

Antitoxin (Protein)

• Gene name: parD
• Uniprot ID: -
• Locus tag: KQ933_RS03905
• Protein ID: WP_216757480.1
• Coordinates: 781586..781834 (-)
• Length: 83 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
KQ933_RS03895 (KQ933_03895)	778506..780821	-	2316	WP_216757478.1	PAS domain-containing sensor histidine kinase	-
KQ933_RS03900 (KQ933_03900)	781299..781589	-	291	WP_216757479.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
KQ933_RS03905 (KQ933_03905)	781586..781834	-	249	WP_216757480.1	type II toxin-antitoxin system ParD family antitoxin	Antitoxin
KQ933_RS03910 (KQ933_03910)	782139..784787	-	2649	WP_216757481.1	aminopeptidase N	-
KQ933_RS33310	785855..785950	-	96	Protein_774	methyl-accepting chemotaxis protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (5-91)

Antitoxin

• Antitoxin ParD (6-64)

Sequences

Toxin

Protein

• Length: 97 a.a.
• Molecular weight: 11367.88 Da
• Isoelectric Point: 4.6627

>T206567 WP_216757479.1 NZ_CP076853:c781589-781299 [Rhizobium sp. WYJ-E13]
MKYRTTFEADRDIIEIYVLGAEQFGVPQSERYVSELFGTFELLADNPQMARERQELTPPMRLHPDQAHLIAYTIREDDIL
IVRVLHSRQDWQSLFT

Nucleotide

• Length: 291 bp

>T206567 NZ_CP102488:2914438-2914695 [Escherichia coli O15:H18]
ATGAATTTATCCCGTCAGGAACAACATACCTTACACGTTCTCGCTAAAGGTAGACGTATTGCGCACGTCCGCGATTCTTC
AGGCCGCGTCACTTCCGTTGAATGCTACAGCCGCGAAGGGCTGTTGCTGACCGACTGCACGCTCGCCGTCTTCAAAAAAC
TCAAAACCAAAAAACTTATCAAGTCCGTCAATGGCCAGCCCTATCGAATCAACACCACCGAGCTGAATAAAGTTCGCGCT
CAGCTCGATAATCGCTAA

Antitoxin

Protein

• Length: 83 a.a.
• Molecular weight: 9293.39 Da
• Isoelectric Point: 5.1726

>AT206567 WP_216757480.1 NZ_CP076853:c781834-781586 [Rhizobium sp. WYJ-E13]
MATMNVSLPDPMKEWVEAQTRTGRYSNASDYVRDLIRRDQERSDKLAELQRLLAEGLESGVSDRSKEDILRAARERLAAG
QA

Nucleotide

• Length: 249 bp

>AT206567 NZ_CP102488:2914707-2915252 [Escherichia coli O15:H18]
ATGACAGTACACCACTTCACTTTTCATATCACAGATAAAAGTGATGCCAGTGATATCCGGGAAGTCGAAACCCGCGCATT
TGGCTTCAGCAAAGAAGCCGATTTAGTGGCCTCTTTACTTGAGGATGAAAGCGCGCGCCCCGCGTTATCGCTGCTAGCCC
GGTATGAAGGCAAAGCCGTCGGGCATATTTTATTTACCCGGGCAACCTTCAAAGGAGAAATGGATTCACCGTTGATGCAC
ATCCTCGCTCCCCTGGCGGTCATACCGGAATACCAAGGGATGGGCGTGGGAGGACGGTTGATACGCACTGGCATCGAGCA
CCTGAGGTTGATGGGCTGCCAGACGGTTTTTGTTCTCGGCCACGCCACCTATTACCCCCGACATGGGTTCGAACCCTGTG
CCGGAGACAAAGGCTATCCGGCACCTTATCCCATCCCGGAGGAGCACAAAGCCTGCTGGATGATGCAATCACTCACCGCT
CAGCCCATGACCCTGACCGGCCACATCCGGTGCGCAGACCCTGATGAAACCGGAGCACTGACGTGA