206565

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) pasABC/RelE-HTH
Location 563058..563535 Replicon chromosome
Accession NZ_CP076853
Organism Rhizobium sp. WYJ-E13

Toxin (Protein)


Gene name pasB Uniprot ID -
Locus tag KQ933_RS02750 Protein ID WP_216757279.1
Coordinates 563266..563535 (+) Length 90 a.a.

Antitoxin (Protein)


Gene name pasA Uniprot ID -
Locus tag KQ933_RS02745 Protein ID WP_216757278.1
Coordinates 563058..563282 (+) Length 75 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KQ933_RS02710 (KQ933_02710) 558248..558577 + 330 WP_216757271.1 NIPSNAP family protein -
KQ933_RS02715 (KQ933_02715) 558574..558933 + 360 WP_216757272.1 antibiotic biosynthesis monooxygenase -
KQ933_RS02720 (KQ933_02720) 559083..560213 + 1131 WP_216757273.1 site-specific DNA-methyltransferase -
KQ933_RS02725 (KQ933_02725) 560336..560701 - 366 WP_216757274.1 nuclear transport factor 2 family protein -
KQ933_RS02730 (KQ933_02730) 560705..561319 - 615 WP_216757275.1 HAD family phosphatase -
KQ933_RS02735 (KQ933_02735) 561322..562413 - 1092 WP_216757276.1 A/G-specific adenine glycosylase -
KQ933_RS02740 (KQ933_02740) 562511..562999 + 489 WP_216757277.1 DUF721 domain-containing protein -
KQ933_RS02745 (KQ933_02745) 563058..563282 + 225 WP_216757278.1 DUF6290 family protein Antitoxin
KQ933_RS02750 (KQ933_02750) 563266..563535 + 270 WP_216757279.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
KQ933_RS02755 (KQ933_02755) 563675..564373 + 699 WP_007818069.1 DsbA family protein -
KQ933_RS02760 (KQ933_02760) 564458..567916 + 3459 WP_216757280.1 chromosome segregation SMC family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-88)

Antitoxin

Relaxosome protein TraY

(4-49)


Sequences

Toxin        


Download         Length: 90 a.a.        Molecular weight: 10416.87 Da        Isoelectric Point: 10.5968

>T206565 WP_216757279.1 NZ_CP076853:563266-563535 [Rhizobium sp. WYJ-E13]
MAWRIEFHRAAERELEKLGRDAASRILRFLNDRNSKLDDPRSVGEALKGSELGNFWKYRVGDYRVIADINDGAVRILIVR
IGNRRDVYR

Download         Length: 270 bp

>T206565 NZ_CP102488:2270786-2271004 [Escherichia coli O15:H18]
ATGTCCGAAAAACCTTTAACAAAAACCGATTATTTAATGCGTTTACGTCGTTGCCAGACAATTGACACGCTGGAGCGTGT
TATCGAGAAAAATAAATACGAATTATCAGATAATGAACTGGCGGTATTTTACTCAGCCGCAGATCACCGCCTCGCCGAAT
TGACCATGAATAAACTGTACGACAAGATCCCTTCCTCAGTATGGAAATTTATTCGCTAA

Antitoxin


Download         Length: 75 a.a.        Molecular weight: 8603.87 Da        Isoelectric Point: 4.6909

>AT206565 WP_216757278.1 NZ_CP076853:563058-563282 [Rhizobium sp. WYJ-E13]
MLALRLPPEIEARLDALAKRTGRSKSFYARQAILEHLDDMEDIFLAEKRLEELRKEETDTVPLSELMARYGVEN

Download         Length: 225 bp

>AT206565 NZ_CP102488:2270386-2270760 [Escherichia coli O15:H18]
ATGGATGAATACTCACCCAAAAGACATGATATCGCACAGCTTAAGTTTCTCTGTGAAACCCTGTATCATGACTGTCTTGC
AAACCTTGAAGAAAGCAATCATGGCTGGGTTAACGACCCAACCTCGGCGATCAACCTCCAGTTGAATGAACTGATTGAGC
ATATTGCGACCTTCGCACTTAATTACAAAATTAAGTATAATGAAGACAATAAGCTCATTGAGCAGATCGACGAATATCTG
GATGACACCTTTATGTTGTTCAGCAGTTATGGTATTAATATGCAGGATCTTCAGAAATGGCGGAAGTCAGGTAATCGACT
ATTCCGTTGTTTTGTCAATGCGACGAAAGAGAATCCTGCGAGTTTATCTTGTTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References